Primary PCI is done: what about the rest? COMPARE ACUTE

The session - entirely devoted to interventional cardiology – started with COMPARE ACUTE, a trial of FFR-guided complete revascularization beyond the culprit lesion in patients with STEMI.

Reported from the American College of Cardiology 2017 Scientific Sessions in Washington.

Compared with conventional conservative treatment (a strategy already challenged by previous trials like PRAMI, CVLPRIT and DANAMI-3), patients who had FFR-guided revascularization of the non-culprit lesion(s) experienced significantly less combined death from any cause, nonfatal myocardial infarction, revascularization, or cerebrovascular events at 12 months.

This benefit was driven essentially by significantly less revascularization, but myocardial infarction also pointed to  the right direction. This trial being open-label, skeptics will argue that differences in revascularization are biased by the knowledge of the underlying angiographic condition, which may prompt the use of more aggressive strategies in patients belonging to the conservative arm.

1 comment

  • Swalehin Bux 13 May 2017

    What is the best way to do complete revascularisation in a case of STEMI. Is it same time while doing culprit vessel angioplasty or on another day but during the same hospitalizsation?


This case report does not reflect the opinion of PCR or PCRonline, nor does it engage their responsibility.