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Just accepted article

Hierarchical testing of composite endpoints: applying the win ratio to percutaneous coronary intervention versus coronary artery bypass grafting in the SYNTAX trial

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1. Erasmus Universiteit Rotterdam, Cardiothoracic surgery, Rotterdam, NETHERLANDS; 2. Netherlands; 3. Department of Biostatistics, Erasmus University Medical Center, Rotterdam, The Netherlands; 4. Department of Cardiology, Erasmus University Medical Center, Rotterdam, The Netherlands; 5. Department of Cardiovascular Surgery, Herzzentrum Universit├Ąt Leipzig, Leipzig, Germany; 6. Academic Medical Center, Amsterdam, The Netherlands; 7. Department of Cardiothoracic Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands

Abstract

Aims: To compare long-term outcomes of percutaneous coronary intervention (PCI) versus coronary artery bypass grafting (CABG), accounting for the clinical impact of individual components in composite endpoints and prioritizing these using the win ratio (Rw).

Methods and results: The win ratio was c…

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