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Five-year Outcome of a Randomized Trial Comparing Second Generation Drug-eluting Stents Using Either Biodegradable Polymer or Durable Polymer: The NOBORI Biolimus-Eluting versus XIENCE/PROMUS Everolimus-eluting Stent Trial (NEXT)


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Masahiro Natsuaki1; Ken Kozuma2; Takeshi Morimoto3; Kazushige Kadota4; Toshiya Muramatsu5; Yoshihisa Nakagawa6; Takashi Akasaka7; Keiichi Igarashi Hanaoka8; Kengo Tanabe9; Yoshihiro Morino10; Hideo Nishikawa11; Takeshi Kimura12;

1. Department of Cardiovascular Medicine, Saga University, Saga, Japan; 2. Division of Cardiology, Teikyo University Hospital, Tokyo, Japan; 3. Department of Clinical Epidemiology, Hyogo College of Medicine, Nishinomiya, Japan; 4. Department of Cardiology, Kurashiki Central Hospital, Kurashiki, Japan; 5. Division of Cardiology, Tokyo Hospital, Tokyo, Japan; 6. Division of Cardiology, Tenri Hospital, Tenri, Japan; 7. Department of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan; 8. Division of Cardiology, Hanaokaseishu Memorial Cardiovascular Clinic, Sapporo, Japan; 9. Division of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan; 10. Division of Cardiology, Iwate Medical University Hospital, Morioka, Japan; 11. Division of Cardiology, Mie Heart Center, Mie, Japan; 12. Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan, JAPAN

Aims: We sought to evaluate the 5-year clinical outcomes of biodegradable polymer biolimus-eluting stent (BP-BES) compared with durable polymer everolimus-eluting stent (DP-EES).

Methods and results: The NOBORI Biolimus…

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