90 results
Outcomes in patients with atrial fibrillation randomized to receive LAA closure or oral anticoagulation: Primary results of the CHAMPION-AF clinical trial
28 Mar 2026
During the first Late-Breaking Trial session of the 2026 ACC Congress held in New Orleans, Saibal Kar, principal investigator of the CHAMPION-AF trial, presented the 3-year results of this groundbreaking study, which were simultaneously published in the NEJM (DOI: 10.1056/NEJMoa2517213).

Author
CLOSURE-AF: left atrial appendage closure or medical therapy in atrial fibrillation
23 Mar 2026
Catheter-based left atrial appendage closure (LAAC) is widely used as an alternative to oral anticoagulation in atrial fibrillation. But how does it compare with best medical therapy in patients at high risk of both stroke and bleeding? The CLOSURE-AF trial provides new data to inform this...

Reviewer
Digital late breakers: will LAAC become standard practice for patients with AF?
12 Mar 2026
Register for free to this webinar on 15 April at 5:00pm (UTC+2) with P. Garot, M. Bergmann and J.E. Nielsen-Kudsk and review current indications for LAAC, and so much more!
New horizons in structural heart disease therapy - Cutting-edge stroke prevention devices: WATCHMAN × SENTINEL
15 Feb 2026 – From PCR Tokyo Valves 2026
This session delves into the advances in stroke prevention for patients undergoing TAVI with atrial fibrillation, focusing on left atrial appendage closure (LAAC) and cerebral protection strategies. It highlights the evolving role of WATCHMAN devices and the SENTINEL Cerebral Protection System, emphasising perioperative stroke risk management...
LAA closure with CT planning: challenging inferior chicken wing morphology
11 Feb 2026
This 77-year-old woman with paroxysmal AF and prior GI bleeding is referred for LAA closure, but CT reveals a shallow, inferior chicken-wing morphology that complicates device selection and planning. How would your Heart Team approach this challenging case?

Author
PCR London Valves 2025: Best of Social Media Coverage
20 Nov 2025
This year’s coverage was built on innovative formats to support one clear strategy: sharing strong messages and high-quality education through well-prepared, creative content. The #PCRLV social media team was led by Pamela Gatto, and divided into 6 tracks: aortic, mitral, tricuspid, closure, imaging and nursing.
Spotlight on a selection of top Late-breaking Trials presented at PCR London Valves 2025
17 Nov 2025
View a snapshot of the results of these 4 trials in valvular and structural interventions presented in London during this year's Heart Team Course!
Complications of LAA closure - Avoidance and management
17 Nov 2025 – From PCR London Valves 2025
Focused on the prevention and management of complications in left atrial appendage (LAA) closure, this session covers recognition of key procedural risks, techniques for safe transseptal puncture, and strategies to prevent and address device embolisation, pericardial effusion, residual leaks, and device-related thrombus, ensuring procedural safety and...
Left atrial appendage occlusion
17 Nov 2025 – From PCR London Valves 2025
This session focuses on the complexities and innovations in left atrial appendage occlusion (LAAO) procedures. It covers transesophageal ICE monitoring, challenges posed by existing atrial septal occluders, combined surgical and percutaneous approaches, and the practical experience with the Ultraseal device. These insights advance understanding of procedural...
Advancing structural heart with 3D ICE and device guidance
17 Nov 2025 – From PCR London Valves 2025
This PCR London Valves 2025 session explores how 3D TEE, 3D intracardiac echocardiography (ICE), and DeviceGuide technology sharpen procedural accuracy, strengthen operator confidence, and streamline decision-making in real time.
You’ll see how clearly defined team roles enhance both safety and efficiency, and how thoughtful workflow integration can reduce...