LAA (Left Atrial Appendage) closure

Find all the latest content on left atrial appendage (LAA) published on this website.

Today, with an aging population, atrial fibrillation is more common and carries with it an increased risk of embolic cerebrovascular accidents. Anticoagulation strategies alone are not sufficient, and as a large proportion of the thrombus involved in these cerebrovascular accidents are seen to arise in the left atrial appendage (LAA), its closure, either surgically or by percutaneous methods, could reduce risk. Learn more about imaging, tools, devices and techniques as well as adjunctive pharmacotherapy, vascular access and bleeding here…

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LAA closure

90 results

Outcomes in patients with atrial fibrillation randomized to receive LAA closure or oral anticoagulation: Primary results of the CHAMPION-AF clinical trial

28 Mar 2026

During the first Late-Breaking Trial session of the 2026 ACC Congress held in New Orleans, Saibal Kar, principal investigator of the CHAMPION-AF trial, presented the 3-year results of this groundbreaking study, which were simultaneously published in the NEJM (DOI: 10.1056/NEJMoa2517213).

Luigi Biasco

Author

Luigi Biasco
CHAMPION-AF: LAAC vs oral anticoagulation in atrial fibrillation

CLOSURE-AF: left atrial appendage closure or medical therapy in atrial fibrillation

23 Mar 2026

Catheter-based left atrial appendage closure (LAAC) is widely used as an alternative to oral anticoagulation in atrial fibrillation. But how does it compare with best medical therapy in patients at high risk of both stroke and bleeding? The CLOSURE-AF trial provides new data to inform this...

Reviewer

Salvatore Brugaletta
LAAC vs medical therapy: insights from CLOSURE-AF

Digital late breakers: will LAAC become standard practice for patients with AF?

12 Mar 2026

Register for free to this webinar on 15 April at 5:00pm (UTC+2) with P. Garot, M. Bergmann and J.E. Nielsen-Kudsk and review current indications for LAAC, and so much more!

New horizons in structural heart disease therapy - Cutting-edge stroke prevention devices: WATCHMAN × SENTINEL

15 Feb 2026 – From PCR Tokyo Valves 2026

This session delves into the advances in stroke prevention for patients undergoing TAVI with atrial fibrillation, focusing on left atrial appendage closure (LAAC) and cerebral protection strategies. It highlights the evolving role of WATCHMAN devices and the SENTINEL Cerebral Protection System, emphasising perioperative stroke risk management...

New horizons in structural heart disease therapy - Cutting-edge stroke prevention devices: WATCHMAN × SENTINEL

LAA closure with CT planning: challenging inferior chicken wing morphology

11 Feb 2026

This 77-year-old woman with paroxysmal AF and prior GI bleeding is referred for LAA closure, but CT reveals a shallow, inferior chicken-wing morphology that complicates device selection and planning. How would your Heart Team approach this challenging case?

Martin W. Bergmann

Author

Martin W. Bergmann
LAA closure with CT planning: challenging inferior chicken wing morphology

PCR London Valves 2025: Best of Social Media Coverage

20 Nov 2025

This year’s coverage was built on innovative formats to support one clear strategy: sharing strong messages and high-quality education through well-prepared, creative content. The #PCRLV social media team was led by Pamela Gatto, and divided into 6 tracks: aortic, mitral, tricuspid, closure, imaging and nursing.

PCR London Valves 2025: Best of Social Media Coverage

Spotlight on a selection of top Late-breaking Trials presented at PCR London Valves 2025

17 Nov 2025

View a snapshot of the results of these 4 trials in valvular and structural interventions presented in London during this year's Heart Team Course!

Selection of top Late-breaking Trials presented at #PCRLV

Complications of LAA closure - Avoidance and management

17 Nov 2025 – From PCR London Valves 2025

Focused on the prevention and management of complications in left atrial appendage (LAA) closure, this session covers recognition of key procedural risks, techniques for safe transseptal puncture, and strategies to prevent and address device embolisation, pericardial effusion, residual leaks, and device-related thrombus, ensuring procedural safety and...

Complications of LAA closure - Avoidance and management

Left atrial appendage occlusion

17 Nov 2025 – From PCR London Valves 2025

This session focuses on the complexities and innovations in left atrial appendage occlusion (LAAO) procedures. It covers transesophageal ICE monitoring, challenges posed by existing atrial septal occluders, combined surgical and percutaneous approaches, and the practical experience with the Ultraseal device. These insights advance understanding of procedural...

Advancing structural heart with 3D ICE and device guidance

17 Nov 2025 – From PCR London Valves 2025

This PCR London Valves 2025 session explores how 3D TEE, 3D intracardiac echocardiography (ICE), and DeviceGuide technology sharpen procedural accuracy, strengthen operator confidence, and streamline decision-making in real time.

You’ll see how clearly defined team roles enhance both safety and efficiency, and how thoughtful workflow integration can reduce...

Advancing structural heart with 3D ICE and device guidance