Holger Nef

Holger Nef

Interventional cardiologist / Cardiologist
Segeberger Kliniken GmbH Abteilung für Kardiologie - Bad Segeberg, Germany

EDUCATION RESPONSIBILITIES AND MEETING ORGANISATION

- After completing his medical studies and doctoral degree at the Albert Ludwig University of Freiburg i. Br. in 2003, Prof. Nef was postgraduated at the Kerckhoff Heart Center in Bad Nauheim, Germany, in the Department of Cardiology (Director: Prof. Dr. C. Hamm) and after transferring at the Justus Liebig University of Giessen in internal medicine and cardiology. Since May 2010 he is an associate professor of internal medicine. Since his promotion to an adjunct professor at the Justus Liebig University of Giessen, Germany, in July 2012 he has served as vice director of the University hospital, Medical Clinic I, Department of Cardiology and is now responsible for the cathlab.

- Since 2015 he is vice president of the Working Group on Interventional Cardiology (AGIK) of the German Society of Cardiology.

- His interests spans from coronary interventions to interventional treatment of structural heart disease. Special interests are new stent technologies and intravascular imaging.

 
ACTIVE AREAS OF RESEARCH

- Prof. Holger Nef has a very high interest in clinical research and has actively participated in the development of the Bioresorbable scaffolds course on PCR edu online.

Latest contributions

Shaping the future of cardiology - A journey of meaningful innovation in structural heart and coronary

22 May 2025 – From EuroPCR 2025

This EuroPCR 2025 session highlights the latest device innovations reshaping interventional cardiology. Learn how the Myval OCTAPRO THV combines predictable deployment with minimal foreshortening for improved outcomes in structural heart procedures. In the coronary space, the session explores the renewed appeal of the “leave nothing behind”...

Shaping the future of cardiology - A journey of meaningful innovation in structural heart and coronary

NSTEMI in patients in post CABG: a challenging combination

15 May 2024 – From EuroPCR 2024

This session focuses on the management of non-ST-elevation myocardial infarction (NSTEMI) in patients who have previously undergone coronary artery bypass grafting (CABG). Attendees will explore various case presentations and discussions on the challenges and treatment strategies for this complex clinical scenario, including the use of intravascular...

NSTEMI in patients in post CABG: a challenging combination

Restoring vessel physiology and function with Dynamx Bioadaptor - The holy grail of PCI

17 May 2023 – From EuroPCR 2023

Join this session to explore the revolutionary Dynamx Bioadaptor and its role in restoring vessel physiology and function. Learn about the specific patient and lesion characteristics that can be safely and effectively treated with this innovative device, gain confidence in the delivery and deployment techniques, understand...

Management of complex non-culprit multivessel disease after STEMI - LIVE case

16 May 2023 – From EuroPCR 2023

Analyze the case of a 69-year-old non-diabetic male patient with mild chronic kidney disease, acute inferior MI and primary PCI on the postero-lateral RCA, whose angiography showed diffuse disease on the proximal CX and second OM (QFR: 0.65), and an intermediate prox LAD lesion (QFR: 0.90).

IVUS...

Management of complex non-culprit MVD after STEMI - LIVE case

How to deal with difficult situations by a multidisciplinary team

19 May 2022 – From EuroPCR 2022

What you should be learning from this EuroPCR 2022 session is how a team interacts badly in a stressful environment, and then how a team interacts well: it's a way of using simulation to improve team training.

How to deal with difficult situations by a multidisciplinary team

Atherectomy devices: when and how to use them?

19 May 2022 – From EuroPCR 2022

Watch this EuroPCR 2022 session to study various cases with severe calcification through which you can understand indications for rotablator or orbital atherectomy (OAS), find out more about the different device components, and learn tips and tricks.

Atherectomy devices: when and how to use them?

How to deal with calcified lesions

17 May 2022 – From EuroPCR 2022

View the recorded case of a 76-year-old former smoker male patient with hypertension and dyslipidemia and a history of distal RCA and mid-LAD PCI in 2003, CABG and AVR in 2007, and pacemaker implantation for total AV Block, referred to the cathlab for CCS III, and...

How to deal with calcified lesions

Aortic stenosis in the younger patient: procedural complications and lifetime management

21 Nov 2021 – From PCR London Valves 2021

Biological, surgical valves and TAVIs are being implanted in younger and younger patients. Since these procedures must be planned in the best possible way to minimize future complications, and because the lifetime management of these patients must be thought of, watch this session to get very useful...

Aortic stenosis in the younger patient: procedural complications and lifetime management

Shock the Rock: new intravascular lithotripsy real-world data and cases

18 May 2021 – From EuroPCR 2021

Watch this session presented by Emanuele Barbato, Holger Nef, Arif Al Nooryani, Alfonso Ielasi, Michael Haude, Margaret McEntegart and Flavio Luciano Ribichini in order to learn how to optimally adopt Intravascular Lithotripsy (IVL) for treatment of calcified lesions, to identify best practices when using IVL in different clinical settings,...

Shock the Rock: new intravascular lithotripsy real-world data and cases

A comprehensive experience with image-guided robotic PCI

18 May 2021 – From EuroPCR 2021

Watch this session presented by Jean Fajadet, Bruno Farah, William Wijns, J. Aaron Grantham, Helge Möllmann and Holger Nef in order to understand the value of robotics in daily PCI practice, to learn through user experiences how angiography-based physiology and robotic assistance work together to improve patient...

A comprehensive experience with image-guided robotic PCI

Abstracts on Stable CAD - PCR e-Course 2020

25 Jun 2020 – From PCR e-Course 2020

View a selection of abstracts from PCR e-Course 2020 on the topic of Stable CAD:

  • Safety and effectiveness of lithotripsy in calcified eccentric coronary lesions
  • Constant resistance ratio of a pressure microcatheter validated using iFR
  • Virtual stenting algorithm from FFR pullback: a proof of concept study
Abstracts on Stable CAD - PCR e-Course 2020

Are Lower MR Grades Within Our "Clasp"? – PASCAL Repair System Experience

Watch this session to know more about the transcatheter PASCAL Repair System for the treatment of mitral regurgitation and its clinical and commercial experience.

Are Lower MR Grades Within Our 'Clasp'? – PASCAL Repair System Experience

Shockwave IVL Safety and Performance in Eccentric Calcified Coronary Lesions

Watch this Investigator Interview if you want to understand the challenges of treating eccentric calcium, to learn about the initial IVL clinical experience in eccentric calcium and to realise best practices when treating eccentric calcium with IVL

Speaker: Holger Nef

This interview supported by Shockwave Medical was filmed at...

Shockwave IVL Safety and Performance in Eccentric Calcified Coronary Lesions

The Edwards PASCAL transcatheter valve repair system - Latest innovation in transcatheter mitral valve therapy

19 Nov 2019 – From PCR London Valves 2019

Consult this session to learn more about the PASCAL repair system, and discover the essential role of imaging in planning and performing a successful PASCAL repair system procedure thanks to a variety of clinical cases.

The Edwards PASCAL transcatheter valve repair system

Challenging clinical scenarios in valve interventions - Hosted by Germany, Spain and Singapore

18 Nov 2019 – From PCR London Valves 2019

Consult this session to discover various challenging clinical cases and complications in valve interventions, such as MitraClip for cardiogenic shock,  repositionning of a dislodged ALLEGRA transcatheter aortic valve, delayed coronary obstruction, percutaneous closure of a posterior leaflet perforation, and more!

Challenging clinical scenarios in valve interventions - Hosted by Germany, Spain and Singapore

Myocardial infarction non-obstructive coronary arteries - What should I do?

24 May 2019 – From EuroPCR 2019

Consult this session on myocardial infarction to understand how to diagnose non-obstructive causes, to learn how to use imaging to confirm the diagnosis and how to guide treatment for patients presenting with this injury.

Myocardial infarction non-obstructive coronary arteries - What should I do?

Nightmare complications of left main PCI

23 May 2019 – From EuroPCR 2019

Consult this session to learn all about how to anticipate and prevent severe left main complications and how to successfully manage left main complications such as dissection, perforation and stent loss.

Nightmare complications of left main PCI

BRS cases with poor outcomes

22 May 2019 – From EuroPCR 2019

Consult this session to discover various clinical cases where the use of a bioresorbable scaffold ended up in a poor outcome, such as an aneurysm, a thrombosis, and more!

BRS cases with poor outcomes

BRS cases with great outcomes

22 May 2019 – From EuroPCR 2019

Consult this session to discover cases using bioresorbable scaffolds (BRS), and learn more about how / when to use them, and the clinical outcomes they offer.

BRS cases with great outcomes

Bioresorbable scaffold: new data, new hope?

22 May 2019 – From EuroPCR 2019

Consult this session on bioresorbable scaffold (BRS) to learn about new data and clinical outcomes: FAMTOM II trial, BIOSOLVE-IV registry, and more!

Bioresorbable scaffold: new data, new hope?

Coronary lithotripsy in complex calcified lesions

21 May 2019 – From EuroPCR 2019

Consult this session on coronary lithotripsy, and discover how this novel procedure may facilitate the treatment of complex calcified lesions, such as undilatable stenosis, refractory in-stent restenotic lesions, and more!

Coronary lithotripsy in complex calcified lesions