293 results
Ten trials from AHA 2025
12 Nov 2025
Alessandro Sticchi provides us with a curated overview of the late-breaking trials he found most relevant for interventional cardiologists from AHA 2025.

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Renal, inflammation and protection strategies in PCI
11 Oct 2025 – From AICT-AsiaPCR 2025
Delve into renal protection and inflammation management strategies in PCI, with a focus on renal blood flow indicators in chronic heart failure, the protective role of exosomes in myocardial ischemia, and efficacy of renal guard devices against contrast-induced nephropathy. The session also examines radial artery occlusion...
STEMI, thrombus and emergencies
10 Oct 2025 – From AICT-AsiaPCR 2025
Focused on STEMI and acute thrombotic emergencies, this session presents a series of challenging cases involving heavy thrombus burden, acute total occlusions, and complex primary angioplasty scenarios. It explores innovative approaches beyond stenting, the role of drug-coated balloons in plaque erosion, and strategic decision-making in managing...
Complex coronary challenges and anomalies
10 Oct 2025 – From AICT-AsiaPCR 2025
This session explores complex coronary challenges and anatomical anomalies encountered in clinical practice. Topics include management of thrombus showers from unexpected culprits, ultra-low contrast angioplasty in mesenteric ischemia, advanced bifurcation PCI techniques with IVUS guidance, and troubleshooting difficult stent delivery scenarios in calcified lesions and challenging...
Coronary interventions: access, devices and outcomes
10 Oct 2025 – From AICT-AsiaPCR 2025
This session delves into the latest developments in coronary interventions, highlighting advances in vascular access techniques, innovative devices, and clinical outcomes. Topics include endothelial progenitor cell dysfunction in restenosis, the efficacy of distal radial artery (DRA) puncture and sheathless catheters in underserved areas, the use of...
NSTEMI, complex ACS and anatomy
10 Oct 2025 – From AICT-AsiaPCR 2025
This session focuses on complex cases involving non-ST elevation myocardial infarction (NSTEMI), acute coronary syndromes (ACS), and challenging coronary anatomy. It presents unique clinical scenarios such as pediatric rescue PCI, management of significant distal lesions with proximal PCI, anatomical variations complicating interventions, mixed cardiovascular disease management,...
Calcium nodule in circumflex ostium: a complex problem
31 Oct 2025
Analyse this case of an 83-year-old male patient, hypertensive, ex-smoker, with severe COPD and peripheral arterial disease with unstable angina. Coronary angiography revealed a severely calcified lesion in a complex anatomical area, making revascularisation a therapeutic challenge.

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DAPT-SHOCK-AMI trial: Cangrelor in cardiogenic shock
03 Sep 2025
Kalaivani Mahadevan and Fizzah Choudry provide their take on DAPT-SHOCK-MI presented by Zuzana Motovska at ESC Congress 2025 in Madrid.

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Optical coherence tomography- vs angiography-guided coronary stent implantation in calcified lesions: the ILUMIEN IV trial
28 Aug 2025
In the overall population (n = 2,114), there was a significant interaction between the effect of randomisation to OCT guidance vs angiography guidance in lesions with moderate/severe calcification (n = 1,082) vs no/mild calcification (n = 1,032) on the 2-year rate of TVF (Pinteraction = 0.01).

Reviewer
TACSI: Dual or single antiplatelet therapy after CABG in patients with acute coronary syndrome
03 Sep 2025
Aaysha Cader provides her take on TACSI presented by Anders Jeppsson at ESC Congress 2025 in Madrid.

Author
NEO-MINDSET: Early withdrawal of aspirin after percutaneous coronary intervention for acute coronary syndrome
02 Sep 2025
Daniele Giacoppo reports and provides his perspective on the main results of the ambitious NEOMINDSET trial, presented by Pedro Lemos from the Hospital Israelita Albert Einstein, São Paulo, Brazil, during a Late Breaking Trials session at the ESC Congress 2025 in Madrid, and simultaneously published in the New...

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Duration of DAPT in ACS: The DUAL-ACS Trial
31 Aug 2025
Ali Nazmi Calik interviews David Newby on the landmark DUAL-ACS trial results he presented at ESC Congress 2025 in Madrid.
The trial compared 3 months versus 12 months of dual antiplatelet therapy (DAPT) after myocardial infarction in an all-comer population. Findings suggest that shorter therapy may offer better...

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One- versus three-month DAPT after everolimus-eluting stent implantation in diabetic patients at high-bleeding risk: results from the XIENCE Short DAPT programme
17 Jun 2025
This analysis from the XIENCE Short DAPT programme compared the safety and efficacy of one-month versus three-month DAPT in high-bleeding risk patients with and without diabetes mellitus (DM) following PCI with everolimus eluting stents (EES).

Reviewer
Outcomes after CABG compared with FFR-guided PCI in patients presenting with acute coronary syndrome
10 Jun 2025
This prespecified analysis of the Fractional Flow Reserve versus Angiography for Multivessel Evaluation (FAME 3) trial examined the impact on cardiovascular outcomes of treatment by CABG versus FFR-guided PCI in patients with three vessel disease (3-VD), stratified by acute (NSTEMI) or chronic coronary syndrome (CCS) presentation.

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Recurrent events analysis of MASTER DAPT: total ischemic and bleeding events after abbreviated vs prolonged DAPT in HBR patient
04 Jun 2025
This exploratory analysis from the MASTER DAPT trial evaluates the effect of abbreviated versus prolonged DAPT on total ischaemic and bleeding events in high-bleeding-risk patients from the MASTER DAPT trial.

Reviewer
Overcoming complex anatomy in NSTEMI
23 May 2025 – From EuroPCR 2025
Explore advanced interventional strategies addressing complex anatomy in NSTEMI patients. This session presents challenging cases including unusual STEMI presentations with cardiogenic shock in Takayasu arteritis, subtotal aorto-ostial lesions in young patients, and management of giant coronary artery aneurysms, emphasizing tailored approaches to optimize outcomes.
How coronary physiology may help in guiding treatment of NSTEMI
23 May 2025 – From EuroPCR 2025
This session explores the utility of coronary physiology in guiding NSTEMI treatment. Topics include ischemia with non-obstructive arteries, QFR quality assessment, FFR-CT impact, revascularization deferral, and sex differences in FFR-guided strategies for acute myocardial infarction with multivessel disease.
Calcified un-dilatable lesions in ACS: what should I do?
22 May 2025 – From EuroPCR 2025
Address the challenges of severely calcified undilatable lesions during acute coronary syndrome PCI. This session reviews the impact of coronary calcification on PCI strategy, highlights pitfalls in lesion preparation, and presents detailed case studies demonstrating effective treatment approaches.
Bifurcation CAD: presentation and PCI strategies
22 May 2025 – From EuroPCR 2025
Navigate the complexities of coronary bifurcation disease with a comprehensive session covering decision-making, imaging applications, and PCI strategies. Review clinical scenarios involving left main disease, calcifications, and acute presentations. Understand the pivotal role of intracoronary imaging and explore provisional and two-stent techniques through detailed case discussions...
Challenging left main PCI in NSTEMI patients
22 May 2025 – From EuroPCR 2025
Address the complexities of left main PCI in NSTEMI patients with challenging clinical presentations. This session discusses management of complex left main bifurcation disease, early graft failure guided by imaging and physiology, revascularization strategies for coronary left main occlusion, PCI complications requiring CTO techniques, and acute...