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Mitral valve replacement and repair

Find all the latest content on mitral valve replacement and repair published on this website.

Building on the years of experience with TAVI, mitral valve replacement and repair is now beginning to take-off with a vast array of new techniques and options. Certain devices, for instance in mitral repair, are now widely used. To understand this complex field a knowledge and mastery is required covering the latest research, emerging tools, devices and techniques, vascular access; the role of adjunctive pharmacotherapy; imaging techniques such as echocardiography as well as understanding bleeding risks or patient selection. Find out more…

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Mitral valve replacement and repair

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Mixed mitral valve disease in an irradiated chest with eggshell-like left atrium

22 Dec 2025

Managing mixed mitral valve disease is particularly challenging in patients with prior chest irradiation and extensive calcification.

A 40-year-old man presents with severe symptomatic MR, renal impairment, and an unusual eggshell-like left atrium. Imaging reveals complex mitral anatomy and critical constraints for transcatheter therapy.

How would you approach...

Konstantinos Spargias

Author

Konstantinos Spargias
Mixed mitral valve disease in an irradiated chest with eggshell-like left atrium

Severe mitral regurgitation in a high-risk patient with a suboptimal anatomy for M-TEER: what other options can we find?

21 Dec 2025

A 78-year-old male presents with recurrent HFpEF hospitalisations and severe degenerative MR. Multimodality imaging reveals fibro-calcific leaflet disease, restricted motion, and a short posterior leaflet, making him a suboptimal candidate for M-TEER and prompting consideration of transcatheter mitral valve replacement. How would you treat?

Author

Federico De Marco

Author

Elena Dipietro

Author

Matteo Biroli
Severe mitral regurgitation in a high-risk patient with a suboptimal anatomy for M-TEER: what other options can we find?

M-TEER with Mitraclip Gen5

19 Dec 2025

An 83-year-old female patient with HFrEF due to NICM and a history of arterial hypertension and persistent atrial fibrillation was referred with worsening exertional dyspnea, severe functional mitral regurgitation and moderate tricuspid regurgitation.

How would you treat this patient?

 

Tobias Kister

Author

Tobias Kister
M-TEER with Mitraclip Gen5

One price, unlimited learning: Holiday PCR Publishing offer

18 Dec 2025

Celebrate the season with our exclusive Christmas offer! Choose any digital subscription - EuroIntervention and/or The PCR Textbook – for €85.

Holiday Special: Any digital subscription for just €85 from 18 to 22 December only!

Abstracts - Part 2

11 Dec 2025 – From GulfPCR-GIM 2025

This session compiles recent clinical abstracts addressing diverse topics in interventional cardiology. Highlights include the HYBRID-CTO approach from a prospective case series, the cardiovascular impact of empagliflozin in type 2 diabetes, off-label use of intravascular lithotripsy for resistant in-stent lesions, and experiences with non-hyperaemic pressure ratios...

Innovation and teamwork in structural heart interventions

11 Dec 2025 – From GulfPCR-GIM 2025

This session explores innovations and collaborative approaches in structural heart interventions, focusing on aortic and mitral valve procedures. It addresses procedural indications, challenges, and the evolving roles of non-physician allied professionals. Interactive elements foster knowledge exchange and support the growth of expertise in the structural heart...

PCR London Valves 2025: Best of Social Media Coverage

20 Nov 2025

This year’s coverage was built on innovative formats to support one clear strategy: sharing strong messages and high-quality education through well-prepared, creative content. The #PCRLV social media team was led by Pamela Gatto, and divided into 6 tracks: aortic, mitral, tricuspid, closure, imaging and nursing.

PCR London Valves 2025: Best of Social Media Coverage

Transcatheter mitral valve replacement in practice

18 Nov 2025 – From PCR London Valves 2025

This session provides an in-depth overview of transcatheter mitral valve replacement (TMVR) in clinical practice, focusing on patient and anatomical suitability assessments including imaging parameters and risk factors for left ventricular outflow tract obstruction. It covers anatomical preparation techniques such as leaflet modification, prior clip removal,...

Transcatheter mitral valve replacement in practice

From GDMT to TEER: management of secondary mitral regurgitation and the timing of transcatheter intervention

18 Nov 2025 – From PCR London Valves 2025

Delve into the comprehensive management of secondary mitral regurgitation, from guideline-directed medical therapy (GDMT) to transcatheter edge-to-edge repair (TEER). This session elucidates the pathophysiology of atrial and ventricular secondary mitral regurgitation, explores optimized heart failure treatments, and reviews the latest evidence on TEER as a therapeutic...

From GDMT to TEER: management of secondary mitral regurgitation and the timing of transcatheter intervention

Mitral TEER in complex scenarios

18 Nov 2025 – From PCR London Valves 2025

This session presents complex clinical scenarios in mitral transcatheter edge-to-edge repair (TEER), illustrating advanced procedural techniques and multidisciplinary management. Topics include on-circuit aspiration thrombectomy to facilitate TEER, combined interventions addressing multiple valve pathologies, timing considerations in healed mitral endocarditis, and TEER application in end-stage idiopathic cardiomyopathy....