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Mitral valve replacement and repair

Find all the latest content on mitral valve replacement and repair published on this website.

Building on the years of experience with TAVI, mitral valve replacement and repair is now beginning to take-off with a vast array of new techniques and options. Certain devices, for instance in mitral repair, are now widely used. To understand this complex field a knowledge and mastery is required covering the latest research, emerging tools, devices and techniques, vascular access; the role of adjunctive pharmacotherapy; imaging techniques such as echocardiography as well as understanding bleeding risks or patient selection. Find out more…

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Mitral valve replacement and repair

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PCR London Valves 2025: Best of Social Media Coverage

20 Nov 2025

This year’s coverage was built on innovative formats to support one clear strategy: sharing strong messages and high-quality education through well-prepared, creative content. The #PCRLV social media team was led by Pamela Gatto, and divided into 6 tracks: aortic, mitral, tricuspid, closure, imaging and nursing.

PCR London Valves 2025: Best of Social Media Coverage

Transcatheter solutions for failed mitral TEER

18 Nov 2025 – From PCR London Valves 2025

This session presents innovative transcatheter solutions for managing failed mitral TEER procedures. It highlights advanced closure strategies for inter-clip mitral regurgitation, percutaneous approaches for recurrent mitral regurgitation, novel chordae tendineae replacement techniques, and potential bailout strategies including atrial flow regulation implantation for recurrent heart failure.

Unusual structural interventions - Part 2

18 Nov 2025 – From PCR London Valves 2025

This session highlights unusual structural interventions in cardiology, featuring comprehensive CT screening for left atrial appendage closure, management of procedural complications, novel access techniques for balloon aortic valvuloplasty, transcatheter treatment of mitral bioprosthetic valve vegetation, and percutaneous ventricular septal rupture closure success criteria.

Complications of mitral TEER

18 Nov 2025 – From PCR London Valves 2025

This session addresses complications associated with mitral transcatheter edge-to-edge repair (TEER), showcasing innovative bailout methods such as snare-assisted retrieval of undeployed devices, managing leaflet perforations with latest-generation devices, cases of valve-adjacent tears, mechanical support considerations when pumps fail, and the clinical impact of iatrogenic fossa ovalis...

Featured research - Mitral valve interventions - Part 4

18 Nov 2025 – From PCR London Valves 2025

This research-focused session presents contemporary evidence and clinical outcomes related to mitral valve interventions. It includes data on transapical mitral valve-in-ring implantation from the European Tendyne registry, prognostic utility of CT-derived fatty muscle fraction in mitral TEER, and comparative outcomes between transapical TMVR and mitral TEER....

Mitral TEER in complex scenarios

18 Nov 2025 – From PCR London Valves 2025

This session presents complex clinical scenarios in mitral transcatheter edge-to-edge repair (TEER), illustrating advanced procedural techniques and multidisciplinary management. Topics include on-circuit aspiration thrombectomy to facilitate TEER, combined interventions addressing multiple valve pathologies, timing considerations in healed mitral endocarditis, and TEER application in end-stage idiopathic cardiomyopathy....

Complex combined transcatheter interventions

18 Nov 2025 – From PCR London Valves 2025

This session addresses complex combined transcatheter interventions for multivalvular heart disease. It covers integrated transcatheter strategies for multiple valve pathologies, solutions for combined severe aortic stenosis and mitral regurgitation with heavy calcification, and approaches to concomitant atrial functional mitral and tricuspid regurgitation. The session also discusses...

Challenging mitral interventions

18 Nov 2025 – From PCR London Valves 2025

This session explores the complexities of mitral interventions, highlighting advancements and challenges in transcatheter mitral valve repair (TMVR). Topics include the benefits of a simplified single-step TMVR approach, the influence of hemodynamic parameters on MitraClip therapy outcomes, strategies for managing persistent pulmonary oedema, and approaches to...

Paravalvular leak closure - Part 4

18 Nov 2025 – From PCR London Valves 2025

This session delves into the complexities of paravalvular leak closure with a focus on challenging scenarios including unusual TAVI complications in the mitral position, management of mega paravalvular leaks using jumbo devices, and strategies when closure itself poses an obstacle. It also covers acute peri-operative aortic...

Cardiovalve hits the TARGET: advancing transcatheter valve replacement

18 Nov 2025 – From PCR London Valves 2025

This session highlights the features and procedural steps of the next-generation Cardiovalve systems for tricuspid and mitral valve replacement. It reviews interim results from the TARGET study, emphasizing echocardiographic findings and reverse remodeling effects, and discusses best practices for patient selection and the learning pathway to...

Cardiovalve hits the TARGET: advancing transcatheter valve replacement