LAA (Left Atrial Appendage) closure

Find all the latest content on left atrial appendage (LAA) published on this website.

Today, with an aging population, atrial fibrillation is more common and carries with it an increased risk of embolic cerebrovascular accidents. Anticoagulation strategies alone are not sufficient, and as a large proportion of the thrombus involved in these cerebrovascular accidents are seen to arise in the left atrial appendage (LAA), its closure, either surgically or by percutaneous methods, could reduce risk. Learn more about imaging, tools, devices and techniques as well as adjunctive pharmacotherapy, vascular access and bleeding here…

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LAA closure

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Device-related thrombosis after percutaneous left atrial appendage occlusion for atrial fibrillation

04 Apr 2018

Salvatore Brugaletta


Salvatore Brugaletta

Randomised Trials in percutaneous treatment for structural heart disease

On this page you will find a list of randomised trials in percutaneous treatment for structural heart disease, published in some of the world's top cardiology and interventional cardiology journals.

Residual leaks following percutaneous left atrial appendage occlusion: assessment and management implications

A common clinical dilemma is the management of patients with peri-device leak after LAA occlusion. The specific definitions of leak severity, and the longer-term clinical implications are poorly understood.

Complex LAA closure interventions

Access to commented cases presented at EuroPCR 2017. Listen to your peers explaining how they managed particularly complicated cases. Discover their "tricks" to prevent catheter bleeding or perform LAA closure in complex anatomy and more.

3D printing for LAA closure - EuroIntervention

Device sizing for LAA closure using transoesophageal echocardiography (TEE) can be challenging due to complex LAA anatomy. Michaela M. Hell and team investigated whether the use of 3D-printed left atrial appendage (LAA) models based on preprocedural computed tomography (CT) permits accurate device sizing.

Printed MDCT 3D models for prediction of left atrial appendage (LAA) occluder device size: a feasibility study

Salvatore Brugaletta


Salvatore Brugaletta

The AMPLATZER™ Amulet™ – facing the challenge of left atrial appendage occlusion

Over the last decade left atrial appendage occlusion has been a topic of intense clinical research

PFO closure reduces recurrent strokes – a therapeutic promise is finally kept

22 May 2017

In patients with a patent foramen ovale (PFO) and cryptogenic stroke, percutaneous closure of the PFO has long been postulated to reduce the rate of recurrent strokes. However, up until now, trial data has failed to convincingly deliver a message of benefit for such an approach. Although the wait has been long, two recently reported trials finally seem to deliver on the therapeutic promise of PFO closure.

EuroPCR 2017 Highlights: Interventions for Stroke

20 May 2017 - From EUROPCR 2017

Interventional treatment of stroke is the future! M. Roffi and Ö. Göktekin along with L. N. Hopkins, neurosurgeon, explain how interventional cardiologists can respond to this challenge. Robust data supporting mechanical treatment of acute stroke increases daily. Until recently we believed intervention worked only within a 6 hour window, but now, the newly released DAWN trial shows that patient selection, IV r-tPA + clot retrieval can have a positive benefit for up to 24 hours after a stroke. An army of interventionalists is needed to treat the millions of eligible patients!

LAA closure

19 May 2017 – From EuroPCR 2017

Consult this session on LAA closure, that includes a LIVE demonstration from the Cardiovascular Centre, OLV Aalst - Aalst, Belgium.