328 results
NOBLE trial: 10-year outcomes of PCI vs CABG in left main disease
13 Apr 2026
Long-term evidence comparing PCI and CABG for unprotected left main coronary disease has been limited and sometimes conflicting. The 10-year results from the NOBLE trial now provide important clarity on all-cause mortality outcomes with both revascularisation strategies.

Reviewer
Coronary calcification versus thrombus: a deceptive ambiguity revealed in the aftermath of embolisation
07 Apr 2026
Discriminating between coronary calcification and thrombus in acute settings remains a diagnostic challenge with significant implications for interventional decision-making.

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Author
IVUS-guided versus angiography-guided PCI in unprotected left main coronary artery disease – The OPTIMAL trial
31 Mar 2026
Ali Nazmi Calik provides his take on the results of the OPTIMAL trial presented by Luca Testa at ACC.26 in New Orleans.

Author
It is a calcified left main: do it well, do it safely
28 Feb 2026 – From Euro4C Annual Meeting 2026
This session addresses the complexities of percutaneous coronary intervention (PCI) in calcified left main coronary artery disease. It covers comprehensive planning including mechanical circulatory support, intravascular imaging, and bifurcation strategies. Attendees will also learn to anticipate and manage potential complications and apply various tools to ensure...
Impact of complete revascularisation in relation to left ventricular function in patients with ST-segment elevation myocardial infarction and multivessel disease: a post hoc analysis of the COMPLETE randomised trial
05 Feb 2026
This study represents a prespecified subgroup analysis of the COMPLETE randomised trial, a large, international, randomised controlled study comparing a strategy of complete revascularisation with culprit-only percutaneous coronary intervention (PCI) in patients presenting with ST-segment elevation myocardial infarction (STEMI) and multivessel coronary artery disease (MVD).
The present...

Reviewer

Reviewer
Left main bifurcation - LIVE Case
30 Jan 2026 – From SASCI-AfricaPCR
Join this session if you want to understand and optimise treatment strategies for LM bifurcation lesions, specifically: Understanding LM bifurcation anatomy and physiology, choosing the best stent strategy, optimising stent deployment and results.
LIVE Case from Groote Schuur Hospital Cape Town
Provisional stenting for a distal left main stenosis - LIVE Case
Recommended by PCR
10 Dec 2025 – From GulfPCR-GIM 2025
A 66-year-old male with preserved LV function, type II diabetes, and hypertension, presented with CCS and anterior ischemia, with a normal ECG. Photon-counting CT revealed a significant calcified stenosis of the distal left main and proximal LAD, confirmed by coronary angiography.
A stent was implanted in the...
Ten trials from AHA 2025
12 Nov 2025
Alessandro Sticchi provides us with a curated overview of the late-breaking trials he found most relevant for interventional cardiologists from AHA 2025.

Author
Provisional stenting with a scaffold stent and DCB in calcified left main bifucation - LIVE Case
11 Oct 2025 – From AICT-AsiaPCR 2025
A 59-year-old male presented with CCS for three months, with diabetes and normal LV function (72%). Coronary angiography showed a calcified left main stenosis (Medina 1,1,1) and diffuse calcification of the proximal and mid LAD. The LCX QFR was 0.86.
Treatment included extensive lesion preparation with lithotripsy...
Left main PCI - LIVE Case
10 Oct 2025 – From AICT-AsiaPCR 2025
A 78-year-old male with a history of LAD PCI in 1997 presented with an NSTEMI three months earlier due to diffuse three-vessel calcified disease, including: distal LM stenosis, severe mid and distal disease of a dominant RCA, and LAD in-stent restenosis. LV function was normal. He...