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What are the emerging indications for TAVI in 2025?

22 May 2025 – From EuroPCR 2025

Tiffany Patterson, Nicolas Van Mieghem, and Philippe Généreux discuss emerging indications for TAVI in 2025. They review recent evidence on asymptomatic severe aortic stenosis, highlighting four randomised trials—RECOVERY, AVATAR, ONLY TAVR, and EVoLVeD—that show TAVI or surgical AVR reduces hospitalisations for heart failure and trends toward...

What are the emerging indications for TAVI in 2025?

Hotline - ACURATE neo2 under-expansion in the ACURATE IDE study: a post-hoc analysis

21 May 2025 – From EuroPCR 2025

Howard Herrmann and Raj Makkar discuss a sub-study of the ACURATE IDE trial, which examined valve under-expansion detected by fluoroscopy. Among 1,500 patients with aortic stenosis, 22 % of ACURATE neo2 valves showed under-expansion, often linked to heavy valve calcification.

Patients with under-expanded valves faced higher risks...

ACURATE neo2 under-expansion in the ACURATE IDE study: a post-hoc analysis

What are the essentials of the provisional strategy for non-left main true bifurcation lesions?

21 May 2025 – From EuroPCR 2025

Giuseppe Di Gioia and Jens Flensted Lassen explore the essentials of the provisional stenting strategy for non-left main true bifurcation lesions. This stepwise approach offers simplicity while preserving flexibility: start with one stent in the main vessel, and keep the option open for a second if...

What are the essentials of the provisional strategy for non-left main true bifurcation lesions?

First guidelines for the treatment of LM disease issued by SOLACI and SIAC

22 May 2025 – From EuroPCR 2025

During EuroPCR 2025, Cleverson Zukowski and Pablo Lamelas introduce a landmark initiative: the first clinical guidelines for left main disease specifically developed for Latin America.

Published by the Latin American Society of Interventional Cardiology (SOLACI) and the Interamerican Society of Cardiology (SIAC), these recommendations aim to support...

First guidelines for the treatment of LM disease issued by SOLACI and SIAC

How will EARLY-TAVI and NOTION-3 impact TAVI practice?

21 May 2025 – From EuroPCR 2025

When is the right time to perform TAVI—and how should coexisting coronary artery disease be managed? In this interview, Liesbeth Rosseel, Davide Capodanno, and Michael Joner tackle these two timely questions. They share key takeaways from the EARLY-TAVI trial, which demonstrated reduced rehospitalisation with early intervention...

How will EARLY-TAVI and NOTION-3 impact TAVI practice?

Major LBTs from EuroPCR 2025 - Meta-Analysis of individual patient data from the PROTECTED TAVR and BHF PROTECT-TAVI studies

22 May 2025 – From EuroPCR 2025

Stroke remains one of the most feared complications of TAVI—for both patients and physicians. In this EuroPCR 2025 video interview, Bernard Prendergast and Rajesh Kharbanda examine the role of cerebral protection during TAVI procedures, in light of two randomised trials: PROTECTED TAVR and BHF PROTECT-TAVI. While...

Meta-Analysis from the PROTECTED TAVR and BHF PROTECT-TAVI studies

Major EuroPCR 2025 LBT - 4D-ACS: one-month DAPT followed by dose reduction of prasugrel after drug-coated stent insertion in acute coronary syndrome

21 May 2025 – From EuroPCR 2025

In this EuroPCR 2025 interview, Davide Capodanno and Woong Chol Kang discuss antithrombotic therapy in patients with acute coronary syndromes, focusing on the design and outcomes of the 4D-ACS trial. They describe the patient population enrolled in the study and introduce the two de-escalation strategies investigated:...

Major EuroPCR 2025 LBT - 4D-ACS: one-month DAPT followed by dose reduction of prasugrel after DCS insertion in ACS

Benefits of IVUS plus near-infrared spectroscopy in detecting and managing vulnerable plaques

21 May 2025 – From EuroPCR 2025

At EuroPCR 2025, Nilesh Pareek and Thomas Keeble discuss the clinical value and future potential of NIRS IVUS, a dual-modality imaging system developed by Nipro that combines intravascular ultrasound with near-infrared spectroscopy.

The Makoto™ system and Dualpro™ catheter allow real-time identification of lipid-rich plaques by providing both...

Benefits of IVUS plus near-infrared spectroscopy in detecting and managing vulnerable plaques

Learnings from Evolut Low Risk 5-year and SMART 2-year trials : from evidence to practice

21 May 2025 – From EuroPCR 2025

At EuroPCR 2025, Angela McInerney, Didier Tchétché, and Ole De Backer discuss key results from the SMART and Evolut Low Risk trials. The SMART trial compared balloon-expandable and self-expanding valves in small annulus patients, showing better hemodynamics with the Evolut platform at 2 years. The Evolut...

Learnings from Evolut Low Risk 5-year and SMART 2-year trials : from evidence to practice

Redo TAVI: how to treat different TAVI platforms when they fail?

22 May 2025 – From EuroPCR 2025

In this EuroPCR 2025 interview, Tanja Rudolph, Dan Blackman, and Radoslaw Parma take a deep dive into the current understanding of redo TAVR.

Together, they address the main challenges faced in repeat procedures—chiefly, the risk of coronary obstruction and the importance of preserving coronary access, alongside strategies...

Redo TAVI: how to treat different TAVI platforms when they fail?

Advances in the development of drug-coated balloon

22 May 2025 – From EuroPCR 2025

Join Florim Cuculi and Rony Mathew at this EuroPCR 2025 roundtable to assess the evolution of drug-coated balloons (DCBs) and their role in daily practice.

DCBs offer a compelling alternative to stent implantation in selected cases. However, they are not interchangeable—each is built using different drugs, carriers,...

Advances in the development of drug-coated balloon

How to manage the challenges of TAVI in bicuspid disease?

22 May 2025 – From EuroPCR 2025

How should TAVI be adapted to the unique challenges of bicuspid aortic valve disease? In this EuroPCR 2025 discussion, Chiara De Biase, Kentaro Hayashida, and Didier Tchetche explore the key anatomical and procedural considerations for tailoring treatment. From selecting which bicuspid anatomies are suitable for TAVI...

How to manage the challenges of TAVI in bicuspid disease?

Learnings from LANDMARK and Compare-TAVI at 3 years

22 May 2025 – From EuroPCR 2025

At EuroPCR 2025, Andreas Baumbach, Christian Juhl Terkelsen and Didier Tchetche reviewed the latest findings from the LANDMARK and Compare-TAVI 1 trials—both focused on the performance of the Myval balloon-expandable valve.

LANDMARK compared Myval and Myval Octacor to leading self-expanding valves in a randomised controlled trial. At...

Learnings from LANDMARK and Compare-TAVI at 3 years

Focal or diffuse coronary disease: how can PPG measurement contribute to clinical decision-making?

22 May 2025 – From EuroPCR 2025

How can physiology guide treatment decisions beyond ischemia detection? In this round-table recorded at EuroPCR 2025, Thomas Engstrøm, Carlos Collet and Jeroen Sonck examine how pullback pressure gradient (PPG) makes it possible to identify the distribution pattern of coronary artery disease—focal or diffuse—based on a continuous...

Focal or diffuse coronary disease: how can PPG measurement contribute to clinical decision-making?

Latest learnings on the treatment of asymptomatic severe aortic stenosis from the EARLY TAVR

22 May 2025 – From EuroPCR 2025

At EuroPCR 2025, Christopher Cook, Philippe Genereux, and Victoria Delgado discuss key results from the EARLY TAVR study.

In asymptomatic patients with severe aortic stenosis, early intervention was associated with significantly less cardiac damage at 2 years, compared to a surveillance strategy that led to extensive damage...

Latest learnings on the treatment of asymptomatic severe aortic stenosis from the EARLY TAVR

Resilience and continuity of cardiovascular care in times of crises: the RESIL-Card project

20 May 2025 – From EuroPCR 2025

Reflect on cardiovascular care resilience during crises with insights from the RESIL-Card project initiated by the PCR community. This session shares lessons from the pandemic, presents the development of a novel resilience assessment tool, and outlines future timelines to better prepare cardiac care systems for upcoming...

Resilience and continuity of cardiovascular care in times of crises: the RESIL-Card project

TAVI in bicuspid aortic valve disease - LIVE Case

20 May 2025 – From EuroPCR 2025

A 79-year-old male patient with atrial fibrillation and RBBB on ECG presented with symptomatic severe bicuspid aortic stenosis. LV function was preserved, and coronary artery disease was noted in LAD and first diagonal. A 26 mm Sapien Ultra Resilia valve was implanted via dual femoral access,...

TAVI in bicuspid aortic valve disease - LIVE Case

Nurses and allied professionals clinical cases session

20 May 2025 – From EuroPCR 2025

Highlighting the critical role of nurses and allied professionals, this session presents clinical case discussions on managing brachial dissection, rare ACS diagnosis, coronary perforation, and rotablator complications. Emphasis is placed on teamwork and training illustrated by a case of acute transcatheter aortic valve migration to optimize...

Nurses and allied professionals clinical cases session

Stable CAD and multivessel disease

20 May 2025 – From EuroPCR 2025

This session delves into the management of stable coronary artery disease (CAD) with multivessel involvement. Learn how clinical and procedural factors influence revascularisation strategies, debate the merits of complete revascularisation, and explore decision-making processes between anatomical and functional approaches through illustrative cases and expert analysis.

Stable CAD and multivessel disease

Insights into emerging prognostic predictors for patients with coronary artery disease

20 May 2025 – From EuroPCR 2025

Gain insights into emerging prognostic predictors for coronary artery disease patients, including endothelial shear stress as a cardiovascular risk marker, impacts of intravascular imaging stratified by disease pattern, correlations between diastolic blood pressure and SYNTAX score, and long-term wall shear stress risk prediction from the FAME...

Insights into emerging prognostic predictors for patients with coronary artery disease
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