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Mastering simple and complex LAA closure: a step-by-step case-based approach

16 Nov 2025 – From PCR London Valves 2025

This case-based session offers a comprehensive approach to mastering left atrial appendage (LAA) closure, emphasizing the critical role of imaging from pre-procedural planning through execution. It covers patient selection, procedural strategies from experienced operators, device selection tailored to anatomy, and nuanced decision-making during challenging device releases...

Mastering simple and complex LAA closure: a step-by-step case-based approach

Shaping the treatment of mitral regurgitation with the Intrepid transcatheter mitral valve replacement (TMVR) system

17 Nov 2025 – From PCR London Valves 2025

This session presents an in-depth examination of the Intrepid transcatheter mitral valve replacement (TMVR) system, focusing on its role in treating mitral regurgitation. It covers the system's design features, ongoing clinical research, and long-term durability, complemented by detailed analyses of transapical 5-year outcomes and current trial...

Shaping the treatment of mitral regurgitation with the Intrepid transcatheter mitral valve replacement (TMVR) system

Beyond TAVI

16 Nov 2025 – From PCR London Valves 2025

This session offers a glimpse into cutting-edge structural heart interventions beyond TAVI. It introduces novel devices in early development stages targeting aortic valve stenosis and leaflet modification, discusses strategies to facilitate or defer TAVI, and provides opportunities for engagement with early-stage start-up partners innovating in structural...

Single operator TAVI: where expertise meets consistency

18 Nov 2025 – From PCR London Valves 2025

This session addresses the concept of single operator transcatheter aortic valve implantation (TAVI), emphasizing the integration of expertise with procedural consistency. Follow a discussion on the benefits of simplifying TAVI to a single operator approach facilitated by an electronically enabled delivery system. The session offers a...

Single operator TAVI: where expertise meets consistency

Challenging mitral TEER: overcoming access limitations and anatomical challenges

16 Nov 2025 – From PCR London Valves 2025

This session delves into the challenges of mitral transcatheter edge-to-edge repair (TEER), focusing on complex cases such as denied access, patch dehiscence-induced regurgitation, and functional mitral regurgitation due to amyloid cardiomyopathy. It also highlights innovative imaging approaches, including the use of transthoracic echocardiography as a rescue...

Challenging mitral TEER: overcoming access limitations and anatomical challenges

Challenging tricuspid TEER

16 Nov 2025 – From PCR London Valves 2025

This session focuses on the intricacies of transcatheter tricuspid edge-to-edge repair (TEER) addressing iatrogenic tricuspid regurgitation, failed surgical valve repair, and approaches for patients unsuitable for valve replacement. It also examines the management of multiple clip detachments and the procedural nuances required to navigate complex tricuspid...

Complex combined interventions

16 Nov 2025 – From PCR London Valves 2025

This session presents complex combined interventions tackling multiple valvular and structural heart challenges simultaneously. It highlights innovative procedural approaches such as the 'super combo' techniques, strategies for managing deteriorative mitral regurgitation post-tricuspid valve replacement, and comprehensive management of torrential tricuspid regurgitation within rheumatic multivalvular disease contexts,...

Mitral TEER - LIVE Case

16 Nov 2025 – From PCR London Valves 2025

Watch this live case followed by a recorded case, regarding a 75-year-old male with type 2 DM, permanent AF, and severe LV dysfunction (30%), with a history of RCA PCI one month earlier and three hospitalizations for heart failure, presented with severe secondary mitral and tricuspid...

Mitral TEER - LIVE Case

Valve selection in urgent TAVI: evidence from small annulus studies - Hotline

16 Nov 2025 – From PCR London Valves 2025

This session presents cutting-edge research comparing self-expanding and balloon-expandable valves in urgent and emergent TAVI settings, with a focus on small aortic annuli. It includes data from the NAVULTRA and LANDMARK trials, featuring novel biomimetic balloon-expandable valves and early feasibility studies that shed light on valve...

Hotline - TAVI - Part 2

Tricuspid valve interventions in complex scenarios

16 Nov 2025 – From PCR London Valves 2025

This session explores tricuspid valve interventions in complex clinical scenarios, emphasizing emerging techniques such as electrosurgical laceration to enable TTVR, emergency TEER for papillary muscle rupture, and expanded options for difficult valve disease. It also addresses procedural challenges when conventional implantation maneuvers fail, transcatheter alternatives for...

TAVI for pure aortic regurgitation: different animal, different challenges, different approaches

17 Nov 2025 – From PCR London Valves 2025

This session delves into the unique anatomical and pathophysiological challenges posed by pure aortic regurgitation and their impact on treatment strategies. It reviews clinical outcomes with established and new transcatheter devices, and presents emerging technologies that promise to advance therapeutic options for this distinct patient population.

TAVI for pure aortic regurgitation: different animal, different challenges, different approaches

Transcatheter solutions for rare complications

16 Nov 2025 – From PCR London Valves 2025

This session focuses on transcatheter solutions for rare and unexpected cardiovascular complications. It features percutaneous closure techniques for ascending aortic pseudoaneurysms, approaches to challenging procedural detachment issues, comprehensive valvular disease management, and complex repairs for coexisting severe aortic coarctation and stenosis, underscoring adaptive interventional strategies for...

From diagnosis to device: decision-making and planning for mitral valve interventions

17 Nov 2025 – From PCR London Valves 2025

This session offers a comprehensive overview of decision-making and procedural planning for transcatheter mitral valve interventions. It emphasizes patient-specific factors, advanced imaging for valve morphology assessment, device selection, and the integration of emerging technologies to tailor optimal treatment strategies for mitral valve disease.

From diagnosis to device: decision-making and planning for mitral valve interventions

Early Career Research Award Final

17 Nov 2025 – From PCR London Valves 2025

Highlighting pioneering research in structural heart interventions, this session presents studies on the impact of transcatheter tricuspid valve replacement (TTVR) on left ventricular geometry and function, myocardial remodeling in aortic stenosis, physiological responses after mitral and tricuspid edge-to-edge repairs, advancing the understanding of device effects on...

Learning from lived experience and contemporary evidence: shaping the treatment of women with heart valve disease

17 Nov 2025 – From PCR London Valves 2025

This session provides an in-depth exploration of the lived experiences of women with valvular heart disease, emphasizing the unique challenges in detection, diagnosis, treatment, and follow-up. It integrates contemporary evidence and the forthcoming 2025 ESC/EACTS guidelines to offer practice-ready strategies tailored to the management of valvular...

Featured research - Mitral valve interventions: Physiology & device innovation

17 Nov 2025 – From PCR London Valves 2025

This session highlights groundbreaking research on mitral valve interventions featuring advanced transcatheter techniques. Topics include coronary physiology assessment with vFFR in severe mitral regurgitation, predictive versus actual outcomes in TMVR, innovative devices like Epygon and INNOVALVE, and novel approaches such as the ReNiva posterior leaflet replacement...

Featured research - Mitral valve interventions: Physiology & device innovation

Complex valve-in-valve leaflet modification - LIVE Case

17 Nov 2025 – From PCR London Valves 2025

Watch this LIVE case followed by a recorded case, regarding a 79-year-old male with permanent AF and a history of surgical aortic valve replacement in 2010 (Magna Ease 25) who presented with symptomatic bioprosthetic valve stenosis, normal LV function, and no CAD. A Sapien 3 Ultra...

Complex valve-in-valve leaflet modification - LIVE Case

Left atrial appendage occlusion

17 Nov 2025 – From PCR London Valves 2025

This session focuses on the complexities and innovations in left atrial appendage occlusion (LAAO) procedures. It covers transesophageal ICE monitoring, challenges posed by existing atrial septal occluders, combined surgical and percutaneous approaches, and the practical experience with the Ultraseal device. These insights advance understanding of procedural...

TAVI: complex vascular access

17 Nov 2025 – From PCR London Valves 2025

This session addresses the challenges of complex vascular access in transcatheter aortic valve implantation (TAVI). It discusses strategies for navigating difficult thoraco-abdominal aortic anatomies, managing double aortic arches, and overcoming hostile femoral access. Case studies illustrate meticulous planning and innovative solutions essential for successful TAVI in...

Tricuspid interventions: knowns and unknowns

17 Nov 2025 – From PCR London Valves 2025

Explore the evolving landscape of transcatheter tricuspid valve interventions in this session, which presents the latest evidence from registries and randomized trials. Discussions include the new Euro tricuspid regurgitation risk score, clinical controversies, real-world patient scenarios, and insights into optimal medical therapy and device selection to...

Tricuspid interventions: knowns and unknowns
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