Severe mitral regurgitation in a high-risk patient with a suboptimal anatomy for M-TEER: what other options can we find?
A 78-year-old male presents with recurrent HFpEF hospitalisations and severe degenerative MR. Multimodality imaging reveals fibro-calcific leaflet disease, restricted motion, and a short posterior leaflet, making him a suboptimal candidate for M-TEER and prompting consideration of transcatheter mitral valve replacement. How would you treat?
23 Dec 2025
Severe mitral regurgitation in a high-risk patient with a suboptimal anatomy for M-TEER: what other options can we find?
A 78-year-old male presents with recurrent HFpEF hospitalisations and severe degenerative MR. Multimodality imaging reveals fibro-calcific leaflet disease, restricted motion, and a short posterior leaflet, making him a suboptimal candidate for M-TEER and prompting consideration of transcatheter mitral valve replacement. How would you treat?
Authors
Director of Interventional, Valvular and Structural Heart Cardiology
Centro Cardiologico Monzino IRCCS - Milan, Italy
Interventional cardiologist / Cardiologist
Policlinico Catania Pad. 8 Cardiologia - Metropolitan city of Catania, Italy
Interventional cardiologist / Cardiologist
Università degli Studi di Milano - Metropolitan City of Milan, Italy
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26 Nov 2025