Managing mixed mitral valve disease is particularly challenging in patients with prior chest irradiation and extensive calcification.
A 40-year-old man presents with severe symptomatic MR, renal impairment, and an unusual eggshell-like left atrium. Imaging reveals complex mitral anatomy and critical constraints for transcatheter therapy.
How would you approach treatment in this high-risk scenario?
27 Feb 2026
Mixed mitral valve disease in an irradiated chest with eggshell-like left atrium
This case has been accredited by EBAC with 1 CME credit
Managing mixed mitral valve disease is particularly challenging in patients with prior chest irradiation and extensive calcification.
A 40-year-old man presents with severe symptomatic MR, renal impairment, and an unusual eggshell-like left atrium. Imaging reveals complex mitral anatomy and critical constraints for transcatheter therapy.
How would you approach treatment in this high-risk scenario?
Author
Interventional cardiologist / Cardiologist
Athens, Greece
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26 Nov 2025