EuroPCR 2025: Late-Breaking Trials and Hotlines
Cutting-edge evidence that shapes clinical decisions
EuroPCR is where education meets evidence, bringing you the latest breakthroughs in interventional cardiology. This year’s Major Late-Breaking Trials session will unveil three pivotal studies selected from the best submissions, while Hotline sessions will provide essential updates on key clinical trials and registries.

✨ Focus on 3 high-impact presentations
3 Major Late-Breaking Trials that have the potential to make a particularly significant impact on your current practice, were selected from the call for submissions. Save space in your agenda for the dedicated session of the programme showcasing these presentations:
- Meta-Analysis of individual patient data from the PROTECTED TAVR and BHF PROTECT-TAVI studies - Rajesh Kharbanda
- Angiography versus physiology-guided PCI in patients undergoing TAVI: the functional assessment in TAVI (FAITAVI) trial Flavio Luciano Ribichini
- One-month DAPT followed by dose reduction of prasugrel after drug-coated stent insertion in Acute Coronary Syndrome Woong Chol Kang
✨Good to know: before unveiling the latest research, the session will open with a tribute to
Jean-Philippe Collet, recognising his contributions to the field.

Hotlines: Unveiling Key Clinical Insights
Beyond Late-Breaking Trials, Hotline sessions provide first-hand access to major trial updates, registry results, and follow-up data that shape clinical decision-making. These fast-paced, high-impact presentations deliver the latest findings from the most relevant studies in interventional cardiology.
Stay up to date with the evidence that matters.
List of sessions and hotlines presented in Paris:
- Two-year outcomes of T-TEER for tricuspid regurgitation: the TRILUMINATE pivotal trial - Gagan Singh
- TRI-SCORE for mortality risk prediction after tricuspid valve TEER – the EuroTR registry - Matthias Groeger
- Management and outcome of failed transcatheter tricuspid edge-to-edge repair: the FATE registry - Federico De Marco
- Two-year real-world outcomes for tricuspid edge-to-edge eepair: the bRIGHT study - Raffi Bekeredjian
- Impact of transcatheter edge-to-edge repair on prognosis in atrial functional mitral regurgitation - Tomohiro Kaneko
- Deferred or conventional stenting in patients with STEMI: 10-year outcome of DANAMI-3-DEFER - Jacob Thomsen Loenborg
- Stent-retriever thrombectomy in STEMI with large thrombus Burden. The randomised RETRIEVE-AMI trial - Rafail Kotronias
- PCI in multivessel disease and STEMI-related cardiogenic shock: A DanGer Shock substudy - Rasmus Paulin Beske
- Complete or culprit-only revascularisation in STEMI: 10-year outcome of DANAMI-3-PRIMULTI - Thomas Engstrom
- FAMOUS-NSTEMI Trial Extended: the prespecified analysis of longer term clinical outcomes - Colin Berry
- TEER for moderate to severe or severe functional mitral regurgitation: DRAGONFLY-FMR study - Georg Nickenig
- Early feasibility experience of posterior leaflet restoration to reduce mitral regurgitation - Ulrich Schaefer
- Feasibility of transfemoral mitral annuloplasty: EU Pilot Trial - First Report - Federico De Marco
- 1-year outcomes of a novel transcatheter edge-to-edge mitral repair system in patients with function - Geng Wang
- Novel 28-French transseptal TMVR system: first-in-human experience - Azeem Latib
- A prospective, multicenter, randomized trial of cutting balloon for the treatment of calcified lesion - Kohei Koyama
- Intravascular lithotripsy vs rotational atherectomy for coronary lesions: results from ICARE-OFDI - Speaker TBD
- Randomised comparison of lithotripsy vs. conventional preparation in severely calcified lesions (BALI) - Andreas Kristensen
- Rotational atherectomy, lithotripsy or laser for calcified coronary stenosis. One-year outcomes - Alfonso Jurado
- The EMPOWER CAD study: women with calcified coronary arteries treated with intravascular lithotripsy - Margaret Mcentegart
- The United Kingdom Transcatheter Aortic Valve Implantation (UK TAVI) trial: Five-year outcomes - William Toff
- Incidence, evolution, and impact of cardiac damage in asymptomatic severe aortic stenosis - Philippe Genereux
- One-year outcomes of contemporary TAVI valves – a randomised, non-inferiority LANDMARK trial - Patrick Serruys
- Three-year results of a randomised study comparing two balloon-expandable TAVI valves - Christian Juhl Terkelsen
- Pooled analysis of two randomised controlled trials comparing balloon-expandable TAVI valves - Christian Juhl Terkelsen
- TAVI with intra- vs. supra-annular self-expanding valves - Pier Pasquale Leone
- Early ACURATE prime: multicenter study to evaluate safety and effectiveness - Andreas Ruck
- ACURATE neo2 under-expansion in the ACURATE IDE study: a post-hoc analysis - Raj Makkar
- Long-term clinical performance of Resorbable Magnesium Scaffolds in Acute Coronary Syndrome - Enrico Cerrato
- Final 7-year outcome of the COMPARE-ABSORB trial - Pieter C. Smits
- Percutaneous coronary treatment with bioadaptor versus stent: 3-year outcomes from BIOADAPTOR-RCT - Shigeru Saito
- Randomized comparison of dual therapy sirolimus-eluting stent vs. biolimus-eluting stent - Ashkan Eftekhari
- A randomised clinical trial on direct stenting versus pre- and postdilatation in stable CAD - Rohit M. Oemrawsingh
- A Randomized Study Comparing Angiography- Guidance with Physiology-Guidance After PCI - Olivier Bertrand
- Clinical and angiographic features of patients likely to have MACE despite online QFR-guided PCI - Hao-Yu Wang
- Prospective Randomized Trial Evaluating Clinical Outcomes of FFRangio Guidance Versus FFR Guidance - Toru Tanigaki
- Prognostic performance of CCTA derived physiology and plaque characterization in the CAREER study - Shengxian Tu
- QFR-PPG for the prognosis of non-culprit vessels in older MI patients with multivessel disease - Stefano Clo
- Outcomes of FFR- vs. angiography-guided PCI in patients with CCS or NSTE-ACS - Fabio Mangiacapra
- Five-year outcomes from the Evolut low risk TAVR bicuspid study - John Forrest
- Surgical versus percutaneous treatment of bicuspid aortic stenosis: a propensity score analysis - Pierre Deharo
- Outcomes of TAVI in patients with native BAV and concomitant aortopathy: the PROSPERO-TAVI study - Giuliano Costa
- Acute valve syndrome and its association with health care cost and resources utilisation before AVR - Philippe Genereux
- 1 year outcomes of transfemoral J-valve for chronic AR: a prospective multicenter study in 127 cases - Lai Wei
- TRiCares Topaz Transfemoral TRICUspid Heart Valve REplacement System First-In-Human Trial - Julien Dreyfus
- 30-day Outcomes of LuX-Valve Plus Transjugular Tricuspid Valve Replacement System in TRINITY Trial - Thomas Modine
- Innovative design for tricuspid regurgitation: early experience with a new TTVR - Joerg Kellermair
- The Trisol TTVR system Technology and EFS Update - Patrick Serruys
- Optical coherence tomography-guided PCI in acute coronary syndrome patients with complex lesions - Byeong-Keuk Kim
- Association between AI-enhanced quantification and target vessel failure after IVUS-guided PCI - Shengxian Tu
- Long-term outcomes after imaging and physiology-guided PCI: Extended follow-up of the FLAVOUR trial - Bon-Kwon Koo
- One-year clinical outcomes of optical coherence tomography-guided percutaneous coronary intervention - Taishi Yonetsu
- Optical coherence tomography-based post-PCI physiology assessment: An ILUMIEN-IV substudy - Thomas Johnson
- A randomized trial of coronary function testing-guided treatment versus standard care in ANOCA - Tim Van De Hoef
- Murray-law based quantitative flow ratio and graft patency after coronary artery bypass grafting - Ho Young Hwang
- Impact of coronary microvascular dysfunction on patient-reported outcomes in patients undergoing PCI - Frederic Bouisset
- Absolute coronary flow and microvascular resistance changes after percutaneous coronary intervention - Federico Marin
- Prognostic value of microvascular function in Takotsubo syndrome: pooled analysis of IPD - Rob Eerdekens
- Ticagrelor monotherapy in chronic coronary syndrome patients post percutaneous coronary intervention - Javad Kojuri
- Multiple events after PCI in patients at high bleeding risk: a MASTER DAPT trial sub-analysis - Marco Valgimigli
- Effect of BB interruption on blood pressure in MI patients: secondary results of the ABYSS trial - Niki Procopi
- Long-term outcomes of 3-to 6-month versus 12-month DAPT after PCI with contemporary stents - Hyo Soo Kim
- Paclitaxel vs sirolimus-coated balloons for CAD: 2-year follow-up of two large registries - Bernardo Cortese
- Clinical Outcomes of Bailout Stenting after Drug-Coated Balloon Angioplasty - Mauro Gitto
- DEB vs DES for the treatment of large native coronary artery disease: a meta-analysis - Jose Antonio Sorolla Romero
- Head-to-head comparison of Limus vs Paclitaxel DCBs in the Treatment of In-Stent Restenosis - Marios Sagris
- Optimal Treatment for Coronary Drug-eluting Stent In-stent Restenosis - Peter Kulyassa
- VELAZQUEZ-EPIC26 study: results of a new hydrodynamic ultrathin strut sirolimus eluting-stent - Jose Antonio Linares Vicente
- Use of CorVad percutaneous ventricular assist system in complex high-risk and indicated patients - Kefei Dou
- SCORE - First report on a multicenter, prospective, all-comers study with the SeQuent SCB - Sylvia Otto
- DCB versus DES for ostial left circumflex lesions - Francesco Tartaglia
- Site-specific antithrombotic therapy: DESyne BDS Plus Trial 24-month outcomes - Alexandre Abizaid