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TRISCEND II: Two-year outcomes of transcatheter tricuspid valve replacement for severe tricuspid regurgitation

31 Mar 2026

Jonathan Curio provides his take on TRISCEND II trial results presented by Vinod H. Thourani at ACC.26 in New Orleans.

Jonathan Curio

Author

Jonathan Curio
TRISCEND II: Two-Year Outcomes Of Transcatheter Tricuspid Valve Replacement For Severe Tricuspid Regurgitation

Sex-specific outcomes after transcatheter or surgical treatment of aortic valve stenosis: the DEDICATE-DZHK6 trial

30 Mar 2026

Women have long been underrepresented in TAVR trials. This article explores the DEDICATE trial’s sex-specific outcomes after TAVI and SAVR, revealing differences in early stroke risk, procedural challenges, and one-year survival in men and women with aortic stenosis.

Ruxandra Sava

Reviewer

Ruxandra Sava
DEDICATE-DZHK6 trial: sex differences in TAVI and SAVR results

ALL-RISE: A large-scale, global randomized trial of coronary physiology derived from conventional angiography compared with an invasive pressure wire-based approach to guide PCI

28 Mar 2026

Mirvat Al Asnag provides her take on the ALL-RISE randomised trial presented by Ajay J. Kirtane at ACC.26 in New Orleans.

Dr. Mirvat Alasnag

Author

Mirvat Alasnag
A large-scale, global randomized trial of coronary physiology derived from conventional angiography compared with an invasive pressure wire-based approach to guide percutaneous coronary intervention

Outcomes in patients with atrial fibrillation randomized to receive LAA closure or oral anticoagulation: Primary results of the CHAMPION-AF clinical trial

28 Mar 2026

During the first Late-Breaking Trial session of the 2026 ACC Congress held in New Orleans, Saibal Kar, principal investigator of the CHAMPION-AF trial, presented the 3-year results of this groundbreaking study, which were simultaneously published in the NEJM (DOI: 10.1056/NEJMoa2517213).

Luigi Biasco

Author

Luigi Biasco
CHAMPION-AF: LAAC vs oral anticoagulation in atrial fibrillation

IVUS-guided versus angiography-guided PCI in unprotected left main coronary artery disease – The OPTIMAL trial

31 Mar 2026

Ali Nazmi Calik provides his take on the results of the OPTIMAL trial presented by Adrian Banning at ACC.26 in New Orleans.

Author

Ali Nazmi Calik
Intravascular ultrasound-guided versus angiography-guided percutaneous coronary intervention in unprotected left main coronary artery disease – The OPTIMAL trial

Two-year outcomes after transcatheter tricuspid repair without cross-over in the randomized Tri-fr trial

28 Mar 2026

Alex Sticchi interviews Erwan Donal on the 2-year outcomes of the TRI-FR randomised trial evaluating transcatheter tricuspid edge-to-edge repair (T-TEER) versus medical therapy alone, as presented at ACC.26 in New Orleans.

Alessandro Sticchi

Author

Alessandro Sticchi
Erwan Donal

Author

Erwan Donal
Two-year outcomes after transcatheter tricuspid repair without cross-over in the randomized Tri-fr trial

HOST-EXAM:10-year follow-up of clopidogrel vs aspirin monotherapy in stable CAD after PCI with drug-eluting stent

30 Mar 2026

Nicola Ryan provides her take on the 10-year follow-up of the HOST-EXAM, which was presented by Hyo-Soo Kim at ACC.26 in New Orleans.

Nicola Ryan

Author

Nicola Ryan
10-year follow-up of clopidogrel vs aspirin monotherapy in stable coronary artery disease after percutaneous coronary intervention with drug-eluting stent

CLOSURE-AF: left atrial appendage closure or medical therapy in atrial fibrillation

23 Mar 2026

Catheter-based left atrial appendage closure (LAAC) is widely used as an alternative to oral anticoagulation in atrial fibrillation. But how does it compare with best medical therapy in patients at high risk of both stroke and bleeding? The CLOSURE-AF trial provides new data to inform this...

Reviewer

Salvatore Brugaletta
LAAC vs medical therapy: insights from CLOSURE-AF

Intravascular lithotripsy or mechanical debulking in complex calcified coronary arteries: multicenter, prospective ROLLING STONE study

19 Mar 2026

The ROLLING STONE registry compares intravascular lithotripsy (IVL) and atherectomy (rotational and orbital) for treating heavily calcified coronary arteries, assessing real-world safety and effectiveness in percutaneous coronary interventions (PCI).

Reviewer

Aaysha Cader
Intravascular lithotripsy or mechanical debulking in complex calcified coronary arteries: multicenter, prospective ROLLING STONE study

Bioresorbable vascular scaffold versus metallic drug-eluting stent in patients at high risk of restenosis: final 7-year results of the COMPARE-ABSORB trial

10 Mar 2026

This study provides the longest available follow-up for first-generation bioresorbable vascular scaffolds and fails to demonstrate any late clinical advantage after complete scaffold resorption.

Emanuele Gallinoro

Reviewer

Emanuele Gallinoro
Bioresorbable vascular scaffold versus metallic drug-eluting stent in patients at high risk of restenosis: final 7-year results of the COMPARE-ABSORB trial