MASTER DAPT: dual antiplatelet therapy after coronary stenting in high bleeding risk patients - interview with Marco Valgimigli

Reported from the European Society of Cardiology ESC Congress 2021

ESC Congress 2021: Discover the interview given by Marco Valgimigli to Luis G. Ortega-Paz for PCRonline about the MASTER-DAPT trial to assess whether one month of dual antiplatelet therapy preserves the net and major adverse cardiovascular events.

  1. Why use precise-DAPT for patient selection? What do you recommend clinicians/interventionists to use in clinical practice?
  2. Why did you select three co-primary endpoints? Why did you assess them in hierarchical order, and why do you choose that order?
  3. MASTER-DAPT was performed with only one stent platform. Do you believe this affects the external validation of your results?
  4. What should we do for the long-term treatment of high-bleeding risk (HBR) patients who completed the DAPT regimen? Restart life-long aspirin SAPT?
  5. What are the future perspectives in the field of HBR and DAPT?
  6. What further research will you be conducting in the field of HBR and DAPT?

Related article:

MASTER-DAPT: “the MASTER of high-bleeding risk trials” - analysis by Luis Ortega Paz

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Authors

Luis Ortega-Paz

Interventional cardiologist / Cardiologist

University of Florida College of Medicine – Jacksonville - Jacksonville, United States of America

Marco Valgimigli

Interventional cardiologist / Cardiologist

Fondazione Cardiocentro Ticino - Lugano, Switzerland

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