
Ralph Stephan von Bardeleben
Latest contributions
Tricuspid TEER: learnings from the 2-year outcomes of TRILUMINATE Pivotal trial & bRIGHT study
20 May 2025 – From EuroPCR 2025
At EuroPCR 2025, Marianna Adamo and Ralph Stephan von Bardeleben discussed the latest findings on tricuspid valve repair using transcatheter edge-to-edge repair (TEER).
The 2-year results from the TRILUMINATE Pivotal trial showed a significant reduction in tricuspid regurgitation, lasting improvements in quality of life, and a notable...

Tricuspid hotline: new devices
22 May 2025 – From EuroPCR 2025
Discover cutting-edge developments in transcatheter tricuspid valve replacement with new device technologies. Review first-in-human trials, early outcomes from multicenter studies, and innovative designs that promise to advance tricuspid regurgitation treatment.

Innovations in TMVR and Intrepid trial updates
21 May 2025 – From EuroPCR 2025
This EuroPCR 2025 session highlights the evolving role of transcatheter mitral valve replacement, focusing on the clinical potential of mitral regurgitation elimination. Get an overview of the current status of the Intrepid TMVR programme, learn about the transition to the 29Fr transfemoral system, and explore how...

Therapeutic choices for TTVIV-TTVIR interventions
21 May 2025 – From EuroPCR 2025
Explore therapeutic choices for transcatheter tricuspid valve-in-valve and valve-in-ring interventions. Case studies cover annular ring expansion, pacing-related infection, jugular vein access valve replacement, Ebstein anomaly, and double valve-in-valve procedures in right heart disease.

How to build a tricuspid programme?
20 May 2025 – From EuroPCR 2025
Learn how to build a successful tricuspid valve programme with a focus on patient screening protocols, heart team roles, and post-procedural management. Gain expert perspectives on organizational requirements, referral optimization, multidisciplinary collaboration, and quality assessment for tricuspid interventions.

RESHAPING the transcatheter treatment of mitral and tricuspid regurgitation
25 Nov 2024 – From PCR London Valves 2024
Join this compelling session focused on the transcatheter treatment of mitral and tricuspid regurgitation. Explore detailed case discussions, including a mitral regurgitation case, a challenging MitraClip procedure, and a severe tricuspid regurgitation case. Discover key takeaways from the RESHAPE, MATTERHORN, and Tri.FR trials, and learn how...

Mastering structural heart intervention with innovations in imaging
25 Nov 2024 – From PCR London Valves 2024
Explore the future of transcatheter mitral and tricuspid therapies in this innovative session. Learn how advanced imaging techniques like CT/fluoro fusion and 4D intracardiac echocardiography are revolutionizing complex procedures, enhancing both safety and outcomes. Hear from experienced operators as they share their insights on the evolving...

Multivalvular disease: diagnostic challenges and treatment strategies for aortic and mitral valve disorders
03 Feb 2024 – From PCR Imaging Valves Madrid 2024
Addressing the complex diagnostic challenges in aortic stenosis and regurgitation, this session examines the timing of treatment initiation and the decision-making process when aortic valve disease coincides with aortic pathology. It also explores the ongoing healthcare burden posed by mitral regurgitation and stenosis, emphasizing the importance...

TAVI essentials: anatomical factors, prosthesis selection, and complication management
02 Feb 2024 – From PCR Imaging Valves Madrid 2024
Discover a comprehensive exploration of critical considerations in TAVI in this section. From anatomical factors guiding the choice between TAVI and SAVR to strategies for selecting the optimal TAVI prosthesis for individual patients, each topic offers essential insights. Gain valuable insights into navigating TAVI for bicuspid...

Intracardiac echocardiography for tricuspid interventions
01 Dec 2023
Watch the replay of this webinar with R. Hahn, M. I. Koerber, S. Lim, F. Praz and R. S. Von Bardeleben to learn about the latest innovation for imaging the tricuspid valve and much more.

An intrepid solution for transfemoral treatment of mitral regurgitation
21 Nov 2023 – From PCR London Valves 2023
In this session, get insights into the APOLLO EU trial and its current progress, obtain a comprehensive understanding of the latest data from the Early Feasibility TF trial, and discern which patients stand to benefit the most from this treatment.

Complex tricuspid interventions
20 Nov 2023 – From PCR London Valves 2023
Consult this session to discover a selection of abstracts regarding tricuspid valve procedures: explore the complexities of long-term right heart remodeling after transcatheter tricuspid annuloplasty, witness the journey from pre-clinical studies to the first-in-man experience with MonarQ tricuspid valve replacement, delve into Tripair, an innovative transcatheter spacer...

Is only fixing functional mitral regurgitation in heart failure patients enough?
20 Nov 2023 – From PCR London Valves 2023
This session offers insights into combo therapy involving Carillon for patients with functional mitral regurgitation. It covers details of the EMPOWER trial, a double-blinded, sham-controlled study, and explores the potential benefits of early treatment for patients with functional mitral regurgitation.

Advancing valve repair: mastering diverse mitral and tricuspid regurgitation anatomies with the PASCAL Precision system
20 Nov 2023 – From PCR London Valves 2023
Participate in this session to stay informed about the latest clinical and real-world evidence for mitral and tricuspid TEER using PASCAL. Explore case-based discussions on mitral regurgitation treatment using PASCAL Precision, and actively participate in an educational tricuspid TEER recorded case procedure featuring the PASCAL Precision.

Expert roundtable: 4D ICE in tricuspid interventions
20 Nov 2023 – From PCR London Valves 2023
Join this session if you want to get familiar with the 4D ICE technology and the key elements of image guidance for tricuspid interventions, understand how 4D ICE can assist in specific procedural steps during challenging tricuspid interventions, and engage in an interactive discussion with experts...

Mitral Late-Breaking Trials: CLASP IID, AltaValve transseptal programme, MitraSwiss in men and women, MiCLASP...
19 Nov 2023 – From PCR London Valves 2023
Discover the mitral late-breaking trials which were presented during PCR London Valves 2023:
- One-year outcomes of transcatheter mitral repair from the CLASP IID Registry
- AltaValve transseptal programme update
- Mitral TEER in men and women from MitraSwiss registry: is equality achieved?
- Combined impact of mitral valve gradients and mitral regurgitation reduction...

PCR Tricuspid Focus Group - referral meeting in Mainz
10 Jul 2023
Join your peers for this meeting on 7 September 2024 in Mainz, Germany!

Knocking mitral regurgitation down to improve outcomes: earlier is better, but better late than never! (Episode 2: the left side)
18 May 2023 – From EuroPCR 2023
Help optimize your patients' prognosis by attending this session! You'll learn how proper patient selection and timely interventions lead to lasting results and how to use the latest real-world registry data to gain insight into the safety and effectiveness of M TEER.

Innovations in TMVR and Intrepid trial updates
18 May 2023 – From EuroPCR 2023
This session explores the innovations in Transcatheter Mitral Valve replacement, with a special focus on the updates from the INTREPID and APOLLO EU trial, as well as patient benefits through case studies.

EuroPCR 2023 Hotlines/Late-Breaking Trials: mitral and tricuspid valves disease
17 May 2023 – From EuroPCR 2023
The presenters share their views on a range of essays and studies. Join them for an update on: Early experience with a d-shape, monoleaflet TMVR system; Outcomes of Mitral Valve-in-Valve, Mitral Valve-in-Ring and Valve-in-Mitral Annular; Calcification: prospective MITRAL; DRAGONFLY-DMR: transcatheter repair by DragonFly device in mitral...

Long-term valve performance for the next decade and beyond
17 May 2023 – From EuroPCR 2023
How can TAVI outcomes be made better for younger patients with longer life horizons? Check-out in this session where you also will be able to gain in the understanding of the structural challenges of providing TAVI services and see how innovation can contribute to optimal outcomes and...

Use of 4D ICE in tricuspid and mitral valve interventions
16 May 2023 – From EuroPCR 2023
Watch this session to know the challenges of TV imaging, to get an overview on 4D ICE technology, and to study both a transcatheter tricuspid valve procedure and a transcatheter mitral valve procedure through different case presentations, that will then be discussed.

Triluminate trial: how these data impact my practice
In this video, members of the PCR Tricuspid Focus Group Nicole Karam and Ralph Stephan von Bardeleben, discuss the results of the Triluminate trial with David Adams and Paul Sorajja. Together they comment on the take-home messages presented during the ACC.23/WCC scientific sessions and how this...

Triluminate trial: deep dive into the outcomes
In this video, members of the PCR Tricuspid Focus Group Nicole Karam and Ralph Stephan von Bardeleben talk with David Adams and Paul Sorajja about the first landmark trial in the field of tricuspid valve disease, Triluminate. Together they discuss the results presented during the ACC.23/WCC...

Multiple VHD: a diagnostic and clinical challenge
11 Mar 2023 – From PCR Imaging Valves Madrid 2023
Consult these presentations on multiple VHD to learn how to deal with combined valvular lesions, how to assess their severity and how to treat them.

Diagnosis and classification of tricuspid regurgitation
11 Mar 2023 – From PCR Imaging Valves Madrid 2023
Watch this session to learn more about the anatomy of the tricuspid valve and its challenges, to know when and how to treat tricuspid regurgitation, and to discover all about the latest classification regarding this condition.

Tricuspid valve intervention - Get it right!
29 Nov 2022 – From PCR London Valves 2022
Watch this session if you want to learn tips and tricks that influence procedural strategy through a real-life case as well as anatomical factors that contribute to tricuspid valve complexity and choice of treatment, followed by the latest clinical data.

Surgical and transcatheter tricuspid intervention: state of the art - LIVE case
29 Nov 2022 – From PCR London Valves 2022
In this PCR London Valves 2022 session, follow 3 stunning case treatments:
- Part 1: Triscupid TEER (Live)
A 78-year-old male with a history of CABG (2015), PM-CRT (2015) and atrial fibrillation, presents a severe TR with an LVEF of 40%, preserved RV function and moderate pulmonary hypertension.
They performed...

Innovations in TMVR and Intrepid trial updates
29 Nov 2022 – From PCR London Valves 2022
Watch this session if you want to gain insights on the APOLLO TMVR trial, the Intrepid trial and to hear about future innovations in mitral replacement.

Innovations in transcatheter tricuspid valve intervention - LIVE case
28 Nov 2022 – From PCR London Valves 2022
Watch two very innovative tricuspid cases you've never seen before:
- Part 1: TR replacement
An 82-year-old male with chronic atrial fibrillation and completely PM dependent for 27 years, presents a symptomatic torrential TR and an enlarged annulus with a great gap. The operators implanted for the first time in...
