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PCR London Valves 2025 Welcome Ceremony

16 Nov 2025 – From PCR London Valves 2025

The PCR London Valves 2025 Welcome Ceremony marks the commencement of the conference, setting the stage for an immersive exploration of the latest advances and innovations in valvular heart disease management with a focus on transcatheter interventions.

PCR London Valves 2025 Welcome Ceremony

Late-breaking evidence in structural and coronary interventions - Part 2

16 Nov 2025 – From PCR London Valves 2025

This session presents the latest data from pivotal late-breaking trials in interventional cardiology. Highlights include one-year results from the ADALA trial, first-in-man use of the Vivasure PerQseal Elite for large hole arterial closure, two-year outcomes of the DragonFly system in China, six-month European outcomes, and insights...

The Top Late-Breaking Trials - Part 2

TAVI valve-in-valve

16 Nov 2025 – From PCR London Valves 2025

This session presents complex valve-in-valve TAVI cases, illustrating advanced techniques such as valve fracture and snaring in difficult anatomies, approaches for pure aortic regurgitation in degenerated surgical valves, and strategies overcoming challenges in stentless bioprostheses and previous aortic repairs.

TAVI in bicuspid anatomy

16 Nov 2025 – From PCR London Valves 2025

Explore the complexities of performing TAVI in bicuspid aortic valve anatomies, with expert discussions on BASILICA tricuspidisation, procedural planning for extreme calcification, valve sizing, and challenges associated with type 0 bicuspid valves and severe calcification.

Featured research: innovations, safety and evolving pathways in modern TAVI care

16 Nov 2025 – From PCR London Valves 2025

This session addresses contemporary challenges in TAVI, including management of acute valve syndrome through service innovations and the application of Valvosoft non-invasive ultrasound therapy in severe aortic stenosis. It also explores complications such as infective endocarditis post-TAVI, evaluates the feasibility of same-day discharge protocols, and assesses...

Featured research: innovations, safety and evolving pathways in modern TAVI care

TAVI: vascular complications

16 Nov 2025 – From PCR London Valves 2025

This session examines vascular complications associated with transfemoral TAVI procedures, featuring challenging cases such as initial procedural obstacles, complex post-TAVI vascular events, and unusual complications. It also explores advanced techniques like intravascular lithotripsy to optimize TAVI outcomes in patients with severe calcific iliofemoral disease.

Complex mitral and tricuspid TEER

16 Nov 2025 – From PCR London Valves 2025

This session highlights complex cases in mitral and tricuspid transcatheter edge-to-edge repair (TEER), addressing challenges such as septal obstacles in patients with old atrial septal occluders, management of residual atrial septal defects post-mitral valve-in-ring replacement, and innovative multidisciplinary approaches. It also covers hybrid transapical mitral valve-in-valve...

TAVI: high coronary risk - Part 2

16 Nov 2025 – From PCR London Valves 2025

This session presents advanced strategies to mitigate high coronary risk during valve-in-valve TAVR procedures, including the LLAMACORN technique and chimney stenting to prevent coronary obstruction. It discusses management of misaligned prostheses, complex aortic and coronary anatomies, and innovative approaches such as stent crush techniques to ensure...

The Silk Road of MedTech

16 Nov 2025 – From PCR London Valves 2025

Discover pioneering MedTech innovations along the Silk Road, including novel sheath designs for minimalist TAVR, self-expanding valves for pure aortic regurgitation, automated CT quantification via deep learning, and first-in-man experiences with cutting-edge valvuloplasty and TEER devices.

New approaches in aortic regurgitation

16 Nov 2025 – From PCR London Valves 2025

Explore new diagnostic and therapeutic approaches for managing aortic regurgitation. This session covers imaging modalities, guideline-directed patient selection, current transcatheter treatment techniques, and emerging TAVI technologies designed specifically for non-calcific aortic valve pathology.

New approaches in aortic regurgitation

Innovations in TAVR: clinical insights and future perspectives

16 Nov 2025 – From PCR London Valves 2025

Presenting featured research on TAVI, this session covers outcomes from centers without on-site cardiac surgery, comparative leaflet modification techniques, conscious sedation protocols, left ventricular health in timing TAVR, and long-term valve durability insights including seven-year follow-up data.

Innovations in TAVR: clinical insights and future perspectives

Cutting-edge research in transcatheter tricuspid valve therapies

16 Nov 2025 – From PCR London Valves 2025

This session highlights cutting-edge research on tricuspid valve interventions, including the impact of inflow gradients on outcomes, global registry data on bicaval valve therapy, patient selection algorithms, and prognostic score validations for severe tricuspid regurgitation.

Cutting-edge research in transcatheter tricuspid valve therapies

Challenging mitral valve-in-valve

16 Nov 2025 – From PCR London Valves 2025

Gain insights into challenging mitral valve-in-valve procedures addressing small cavity anatomy, alignment difficulties, combined LAMPOON and leak closure techniques, and high-risk TMVR cases with complex left ventricular outflow tract obstruction and ECMO support.

TAVI: alternative access

17 Nov 2025 – From PCR London Valves 2025

This session addresses alternative access routes for TAVI in patients with challenging vascular anatomies. It includes innovative approaches such as transapical TAV-in-TAV procedures, transcaval implantation in emergency settings, and techniques for patients with hostile iliofemoral access, showcasing adaptive strategies when conventional access is not feasible.

TAVI valve-in-valve - Challenging clinical scenarios

17 Nov 2025 – From PCR London Valves 2025

This session focuses on the complexities of valve-in-valve TAVI procedures, highlighting challenging clinical scenarios such as managing severely regurgitant rapid deployment valves and degenerated stentless bioprostheses. It provides detailed insights into overcoming procedural barriers and strategies for complex valve-in-valve transcatheter aortic valve replacement (TAVR) interventions.

TAVI valve-in-valve - Challenging clinical scenarios

TAVI: complex vascular access

17 Nov 2025 – From PCR London Valves 2025

This session addresses the challenges of complex vascular access in transcatheter aortic valve implantation (TAVI). It discusses strategies for navigating difficult thoraco-abdominal aortic anatomies, managing double aortic arches, and overcoming hostile femoral access. Case studies illustrate meticulous planning and innovative solutions essential for successful TAVI in...

TAVI: challenging anatomies

17 Nov 2025 – From PCR London Valves 2025

This session explores the management of challenging anatomical conditions in TAVI procedures. Topics include strategies for difficult self-expandable valve delivery angles, addressing complications occurring during and after TAVI, and approaches for patients with severe kyphosis or complex structural abnormalities such as aneurysms and septal anomalies.

Featured Research - TAVI: valve positioning & aortic anatomy

17 Nov 2025 – From PCR London Valves 2025

This session presents pioneering research on transcatheter aortic valve implantation (TAVI), exploring key topics such as the rise of osteogenic progenitors post-TAVI, the impact of transcatheter aortic valve planar tilt on outcomes, and the comparative results of self- versus balloon-expandable valves in patients with dilated ascending...

Featured Research - TAVI: valve positioning & aortic anatomy

TAVI valve-in-valve - Part 4

17 Nov 2025 – From PCR London Valves 2025

This advanced session addresses complex valve-in-valve TAVI procedures, including management of challenging cases involving combined valve-in-valve TAVI and thoracic endovascular aortic repair. It also discusses technical considerations such as retrieval of lost stents in the left main coronary artery and critical aspects of TAV-in-TAV selection, sizing,...

Cardiogenic shock: transcatheter solutions

17 Nov 2025 – From PCR London Valves 2025

This session focuses on transcatheter solutions for cardiogenic shock, highlighting rescue therapies such as mitral clip intervention in hypertrophic obstructive cardiomyopathy, valve-in-valve TAVI during CPR, and sequential mechanical circulatory support. It presents complex clinical cases illustrating stepwise approaches combining mechanical support and percutaneous valve repair to...

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