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PCR: Collaborative, inclusive and global

15 Nov 2025 – From PCR London Valves 2025

At PCR, collaboration and inclusion are at the heart of everything we do.

Together, we create an environment where expertise is shared, talents complement each other, and diversity becomes a strength. It is this collective spirit that drives interventional cardiology forward and inspires innovation every day.

During PCR London...

PCR: Collaborative, inclusive and global

Redo TAVI: how to treat different TAVI platforms when they fail?

22 May 2025 – From EuroPCR 2025

In this discussion, Tanja Rudolph, Dan Blackman, and Radoslaw Parma take a deep dive into the current understanding of redo TAVR.

Together, they address the main challenges faced in repeat procedures - chiefly, the risk of coronary obstruction and the importance of preserving coronary access, alongside strategies...

Redo TAVI: how to treat different TAVI platforms when they fail?

TRIGISTRY: Advancing real-world understanding of tricuspid valve disease

07 Nov 2025

Edoardo Zancanaro interviews Julien Dreyfus and David Messika-Zeitoun about TRIGISTRY, an international registry that builds on the TRI-SCORE — now part of the 2025 ESC guidelines. The study confirms that early referral and optimal reduction of tricuspid regurgitation are key to improving outcomes. The team now...

TRIGISTRY insights

1-year SELUTION DeNovo results: what they mean for daily practice

29 Oct 2025

The SELUTION DeNovo trial, presented by Christian Spaulding at TCT 2025, delivers the first head-to-head comparison between a sirolimus DCB strategy and contemporary DES in PCI.

In this review, Salvatore Brugaletta breaks down the 1-year results and what these findings truly mean for everyday lesion-by-lesion decision-making.

Guillaume Bonnet

Author

Guillaume BONNET

Author

Christian Spaulding

Author

Salvatore Brugaletta
1-year SELUTION DeNovo results: what they mean for daily practice

How to efficiently and safely manage calcified left main disease?

21 May 2025 – From EuroPCR 2025

Nicola Ryan and Flavio Ribichini explore the complexities of calcified left main stem disease, emphasizing the critical role of intracoronary imaging in improving patient outcomes. They discuss the practical use of mechanical circulatory support and debate stenting strategies, offering expert insights on when single or dual...

How to efficiently and safely manage calcified left main disease?

How to manage coronary artery disease in TAVI candidates?

20 May 2025 – From EuroPCR 2025

Martine Gilard, Antonio Mangieri, and Marco Barbanti explore the strategy for handling coronary artery disease in patients undergoing TAVI. Is coronary angiography always required beforehand? Should PCI be performed in all cases—and if so, when? This exchange offers key insights to help guide your decisions on...

How to manage CAD in TAVI candidates?

What are the fundamentals of an upfront two-stent strategy for bifurcation PCI?

21 May 2025 – From EuroPCR 2025

Nicola Ryan explores the fundamentals of an upfront two-stent strategy in bifurcation PCI with Dejan Milasinovic. When the side branch shows significant, high-grade stenosis or extensive disease, direct treatment - via POBA, DCB, or a second stent - may be preferred. Anatomy guides the decision between...

What are the fundamentals of an upfront two-stent strategy for bifurcation PCI?

How to manage current challenges of small aortic annulus?

18 Nov 2025 – From PCR London Valves 2025

Joanna Wykrzykowska and Hélène Eltchaninoff discuss challenges in treating patients with small aortic annuli, which are common, especially in women, and present risks such as higher gradients, coronary occlusion, pacemaker need, and paravalvular leak. Valve selection and positioning are critical, balancing hemodynamics and complication avoidance.

This interview...

How to manage current challenges of small aortic annulus?

How do we meet the needs of women with heart valve disease?

27 Mar 2026 – From PCR London Valves 2025

In this interview, Ellen Ross and Marta Sitges discuss a recent initiative from Global Heart Hub - a patient association - which examined the realities faced by women living with heart valve disease. They outline the gaps identified, the call to action that followed, and how...

How do we meet the needs of women with heart valve disease?

What are the key considerations when managing combined mitral and tricuspid regurgitation?

17 Feb 2026 – From PCR London Valves 2025

Fabien Praz and Neil Fam talk about the management of patients with combined mitral and tricuspid regurgitation, who are often elderly with heart failure and multiple comorbidities. Careful assessment—including echocardiography, hemodynamics, and sometimes CT—is crucial to identify the dominant lesion. Surgery is preferred if feasible, but...

What are the key considerations when managing combined mitral and tricuspid regurgitation?

Is iatrogenic atrial septum defect closure a necessary procedure?

17 Nov 2025 – From PCR London Valves 2025

Philipp Lurz and Saibal Kar discuss iatrogenic atrial septal defects from transseptal procedures. Small ones usually close on their own, while large defects causing significant shunting need closure to prevent right heart overload. Some moderate defects may be beneficial by decompressing the left atrium, so closure...

Is iatrogenic atrial septum defect closure a necessary procedure?

Should we consider TTVR in patients with straightforward anatomy who are eligible for T-TEER?

17 Nov 2025 – From PCR London Valves 2025

Lukas Stolz and Rebecca Hahn discuss advances in transcatheter tricuspid valve intervention, emphasising that reducing tricuspid regurgitation (TR) to mild levels is key for improving patient outcomes, including mortality and heart failure hospitalisations. Decision-making between transcatheter edge-to-edge repair (T-TEER) and transcatheter tricuspid valve replacement (TTVR) depends...

Should we consider TTVR in patients with straightforward anatomy who are eligible for T-TEER?

The D-PACE scoring system Prediction of high-grade conduction disturbances after TAVI

16 Nov 2025 – From PCR London Valves 2025

Michael Joner and Francesco Saia discuss the newly developed D-PACE Score, a tool designed to predict delayed AV block occurring more than 24 hours after TAVI—an unmet clinical need given that current risk models focus mainly on early events. The next steps aim to refine the...

The D-PACE scoring system - Can we predict high-grade conduction disturbances after TAVI?

Why is TAVI a different procedure in patient with pure aortic regurgitation?

15 Nov 2025 – From PCR London Valves 2025

In this video, Juan Granada, Michael Borger and Joao Cavalcante highlight that aortic insufficiency differs from aortic stenosis and is often underestimated. Early, comprehensive evaluation and imaging are crucial. Surgery is standard for severe cases, while TAVI with dedicated devices is an option for high-risk patients.

This...

Why is TAVI a different procedure in patient with pure aortic regurgitation?

What are the key considerations for transcatheter mitral paravalvular leak management?

18 Nov 2025 – From PCR London Valves 2025

Nina Wunderlich and Patrick Calvert discuss mitral paravalvular leaks, which are relatively common. Percutaneous closure is now the default approach, and imaging is central to success: detailed pre-procedural assessment, 3D TOE during the procedure, and careful planning of transseptal puncture. 

This interview was filmed at PCR London...

What are the key considerations for transcatheter mitral paravalvular leak management?

What are the key steps in pre procedural assessment for successful LAA closure?

16 Nov 2025 – From PCR London Valves 2025

Lorenz Räber and Kasper Korsholm highlight why pre-procedural imaging—particularly cardiac CT—has become essential for successful left atrial appendage occlusion (LAAO). They explain that the LAA is highly variable between patients, making detailed planning crucial for safety, device selection, and optimal procedural results.

This interview was filmed at...

What are the key steps in pre procedural assessment for successful LAA closure?

How to manage patients with aortic stenosis and coronary artery disease?

04 Mar 2026 – From PCR London Valves 2025

Tiffany Patterson and Davide Capodanno address the increasingly common scenario of managing coronary artery disease (CAD) in patients undergoing TAVI. With up to half of TAVI candidates presenting with CAD, they highlight new evidence from NOTION-3 showing that revascularization reduces major adverse cardiac events. The takeaway:...

How to manage patients with aortic stenosis and coronary artery disease?

What are the essential aspects of transcatheter LAA closure?

20 May 2025 – From EuroPCR 2025

Ole De Backer and Philippe Garot discuss the rapid evolution of transcatheter left atrial appendage (LAA) occlusion.

They begin by contrasting patient selection in Europe and the US, where approaches diverge significantly: in Europe, very high bleeding risk remains the main criterion, while in the US, LAA...

What are the essential aspects of transcatheter LAA closure?

Preventing distal particles embolization after DCB angioplasty

21 May 2025 – From EuroPCR 2025

At EuroPCR 2025, Aloke Finn and Antonio Colombo share their insights on a specific and often overlooked complication of drug-coated balloon (DCB) angioplasty: particulate embolization.

They begin by clarifying the distinction between this phenomenon and traditional distal embolization, explaining that particulate embolization is iatrogenic and device-related—it is...

Preventing distal particles embolization after DCB angioplasty

Are we undertreating aortic regurgitation?

20 May 2025 – From EuroPCR 2025

At EuroPCR 2025, Victoria Delgado, Helge Möllmann, and Dan Blackman gather to discuss a crucial but often under-addressed challenge in structural heart disease: the under-referral and under-treatment of patients with aortic regurgitation (AR).

The conversation begins with the diagnostic challenges surrounding severe AR, followed by a striking observation—only...

Are we undertreating aortic regurgitation?
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