PCI of aged saphenous vein bypass grafts: easy as 1-2-3
#CardioTwitterCase originally published on Twitter
High-risk PCI of aged saphenous vein bypass grafts can be made safer by combining the techniques of prophylactic intracoronary vasodilators, distal protection devices, and direct stenting.
This case was originally published on Twitter by @DocSavageTJU
Case description
PCI of older saphenous vein grafts (SVG) is associated with a high risk of procedural complications due to their propensity for distal embolization. Distal protection devices, microvascular vasodilators (such as nicardipine), and direct stenting have all been used to reduce the risks of embolization and no-reflow during SVG procedures.
We present a case which illustrates that, by combining these techniques, PCI can be safely and easily performed for complex SVG disease.
The patient was a 55-year-old man with a subtotal lesion in a 15-year-old SVG to the RCA (Figure 1).

Figure 1: Severe lesion in a large 15-year-old SVG to the RCA
PCI was performed with left radial artery access and a 6 Fr multipurpose guiding catheter. Intracoronary nicardipine (200 mcg) was administered prior to distal deployment of a FilterWire (Boston Scientific, Marlborough, MA, USA).
IVUS demonstrated an eccentric bulky lesion with a prominent area of attenuated plaque, suggestive of friable lipid core (Figure 2).

Figure 2: Baseline IVUS showing an eccentric lesion with a large area of attenuated plaque seen from 6 to 8 o’clock (arrow) indicative of a lipid-rich necrotic core
Direct stenting was then performed with a single inflation of a 4.5 mm Synergy drug-eluting stent (Figure 3).

Figure 3: Angiographic result after direct stenting with a single inflation
Post-PCI IVUS confirmed an excellent result with this “one-and-done” approach (Figure 4).

Figure 4: Post-stent result on IVUS
There were no ischemic complications or no-reflow, and the patient was discharged to home later the same day.
Concluding remarks
PCI of older SVG is often approached with trepidation due to the high risk of complications. A strategy which combines prophylactic intracoronary vasodilators, distal protection, and direct stenting can make the procedure as easy as 1-2-3.
Original tweet and Twitter discussion
PCI of old SVG ⤵️ made easy (1/2)➡️ 1. IC nicardipine, 2. Filterwire, 3. Image, 4. Direct stenting. On IVUS note attenuated plaque at 6-8 o'clock (lipid core) #CardioTwitter@mmamas1973@GreggWStone@mirvatalasnag@SVRaoMD@djc795@DLBHATTMD@SandeepNathanMD@fischman_david ️RP pic.twitter.com/HrE7D8APCb
— Michael Savage (@DocSavageTJU) September 14, 2023
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