Pathophysiology of right ventricular volume/pressure load

HF/RV function & TR Educational Series: Episode #2

Summary

Follow Karl-Philipp Rommel as he shares insights on physiology relevant to diagnosing and treating TR-related right heart failure.

In this video you will learn:

  • to recall the unique physiology of right ventricular function
  • to understand the implications of RV pressure and volume load using the pressure-volume-loop framework
  • to illustrate the concept of right ventricular-pulmonary arterial (RV-PA) coupling

Take-home messages of Episode #2

  1. RV function: a unique contraction pattern and physiology
  2. RV-PA coupling: indexes RV function (contractility) to afterload and describes the match of RV and PA properties to optimize RV performance
  3. Tricuspid regurgitation: RV energetic efficiency↓ (stroke work↑ but cardiac output↓), further aggravated by RV dysfunction, effective RV afterload↓
  4. Chronic RV volume overload: low RV contractility and low contractile reserve