295 results
A controlled trial of rivaroxaban after transcatheter aortic-valve replacement (GALILEO)
13 Dec 2019
The GALILEO trial was a randomized, open-label, event-driven, international, multicentre trial comparing two different preventive strategies for thromboembolic complications in patients who underwent successful TAVI and had not established indication for oral anticoagulation.
Reviewer
Reviewer
Efficacy and safety of low-dose colchicine after myocardial infarction (COLCOT)
09 Dec 2019
COLCOT was a double-blind RCT, designed to evaluate 0.5 mg oral colchicine daily as compared with placebo in patients within 30 days of acute myocardial infarction.
Reviewer
Reviewer
Outcomes of transcatheter aortic valve replacement in mixed aortic valve disease
06 Dec 2019
This study compared the outcomes of TAVR in patients with pure Aortic Stenosis (i.e., without or trivial AR) vs. patients with MAVD (AS associated with mild to moderate or severe AR).
Reviewer
Reviewer
Health status after transcatheter vs. surgical aortic valve replacement in low-risk patients with aortic stenosis
05 Dec 2019
Although multiple studies have demonstrated an early health status benefit with TAVI vs. SAVR , this is the first randomized trial to demonstrate a persistent, albeit modest, health status advantage with TAVI at 6 and 12 months—timepoints at which patients are assumed to have recovered fully...
Reviewer
Prosthesis-patient mismatch following transcatheter aortic valve replacement with supra-annular and intra-annular prostheses
03 Dec 2019
The results of this study suggest that the use of self-expandable valves could help reduce the incidence of post-procedural PPM after TAVI, especially in the population with large body size...
Reviewer
Reviewer
Reduced leaflet motion after transcatheter aortic-valve replacement
27 Nov 2019
The GALILEO-4D was a dedicated substudy that sought to evaluate the effect of oral anticoagulation with rivaroxaban on bioprosthetic aortic valve leaflet thickening and motion impairment.
Reviewer
Reviewer
One-year outcomes of angina management guided by invasive coronary function testing (CorMicA)
27 Nov 2019
CorMicA was a randomised control trial comparing medical therapy guided by invasive coronary function testing (CFR, IMR and acetylcholine provocation) versus standard care in 151 patients with symptoms and/or signs of ischaemia with no obstructive coronary artery disease (INOCA).
Reviewer
Reviewer
Femoral versus nonfemoral peripheral access for transcatheter aortic valve replacement
05 Dec 2019
Using the data from the national prospective French registry (FRANCE TAVI), this study compared the characteristics and outcomes of TAVR procedures according to whether they were performed through a femoral or a nonfemoral peripheral access.
Reviewer
Ticagrelor alone versus dual antiplatelet therapy from 1 month after drug-eluting coronary stenting
10 Nov 2019
One of the most discussed limitations of GLOBAL-LEADER is the lack of event adjudication so that the rate of MI, bleeding or stent thrombosis between the two groups were unknown. In this study, events were adjudicated in those patients from the 20 top-enrolling participating sites.
Reviewer
Paclitaxel-coated balloon angioplasty vs. drug-eluting stenting for the treatment of coronary in-stent restenosis
05 Nov 2019
A comprehensive, collaborative, individual patient data meta-analysis of 10 randomized clinical trials (DAEDALUS study)
Reviewer
Reviewer
