300 results
Reduced leaflet motion after transcatheter aortic-valve replacement
27 Nov 2019
The GALILEO-4D was a dedicated substudy that sought to evaluate the effect of oral anticoagulation with rivaroxaban on bioprosthetic aortic valve leaflet thickening and motion impairment.
Reviewer
Reviewer
One-year outcomes of angina management guided by invasive coronary function testing (CorMicA)
27 Nov 2019
CorMicA was a randomised control trial comparing medical therapy guided by invasive coronary function testing (CFR, IMR and acetylcholine provocation) versus standard care in 151 patients with symptoms and/or signs of ischaemia with no obstructive coronary artery disease (INOCA).
Reviewer
Reviewer
Femoral versus nonfemoral peripheral access for transcatheter aortic valve replacement
05 Dec 2019
Using the data from the national prospective French registry (FRANCE TAVI), this study compared the characteristics and outcomes of TAVR procedures according to whether they were performed through a femoral or a nonfemoral peripheral access.
Reviewer
Ticagrelor alone versus dual antiplatelet therapy from 1 month after drug-eluting coronary stenting
10 Nov 2019
One of the most discussed limitations of GLOBAL-LEADER is the lack of event adjudication so that the rate of MI, bleeding or stent thrombosis between the two groups were unknown. In this study, events were adjudicated in those patients from the 20 top-enrolling participating sites.
Reviewer
Paclitaxel-coated balloon angioplasty vs. drug-eluting stenting for the treatment of coronary in-stent restenosis
05 Nov 2019
A comprehensive, collaborative, individual patient data meta-analysis of 10 randomized clinical trials (DAEDALUS study)
Reviewer
Reviewer
Three-year outcomes of the DKCRUSH-V trial comparing DK crush with provisional stenting for left main bifurcation lesions
15 Oct 2019
DKCRUSH-V showed lower rates of target lesion failure at one year in the DKCRUSH arm, mainly driven by increased rates of target vessel MI. In this paper, the authors report the extended follow-up to three years.
Reviewer
Reviewer
Transcatheter aortic valve implantation vs. surgical aortic valve replacement for treatment of symptomatic severe aortic stenosis: an updated meta-analysis
22 Oct 2019
Owing to new evidence from randomized controlled trials in low-risk patients with severe aortic stenosis, the authors compared the collective safety and efficacy of TAVI vs. SAVR across the entire spectrum of surgical risk patients...
Reviewer
Ticagrelor with or without aspirin in high-risk patients after PCI
07 Oct 2019
The TWILIGHT trial was designed to test the hypothesis that in patients undergoing PCI who are at high risk for ischemic or hemorrhagic complications and who have completed a 3-month course of DAPT with ticagrelor plus aspirin, continued treatment with ticagrelor monotherapy would be superior to ticagrelor...
Reviewer
Impact of long-term ticagrelor monotherapy following 1-month dual antiplatelet therapy in patients who underwent complex percutaneous coronary intervention: insights from the Global Leaders trial
16 Sep 2019
GLOBAL LEADERS was a randomized, open-label, superiority trial in patients who underwent PCI with a biolimus A9-eluting stent for stable CAD or ACS...
Reviewer
Reviewer
Cognitive decline before and after incident coronary events
05 Sep 2019
Reviewer
Reviewer
