297 results
Ticagrelor alone versus dual antiplatelet therapy from 1 month after drug-eluting coronary stenting
10 Nov 2019
One of the most discussed limitations of GLOBAL-LEADER is the lack of event adjudication so that the rate of MI, bleeding or stent thrombosis between the two groups were unknown. In this study, events were adjudicated in those patients from the 20 top-enrolling participating sites.

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Paclitaxel-coated balloon angioplasty vs. drug-eluting stenting for the treatment of coronary in-stent restenosis
05 Nov 2019
A comprehensive, collaborative, individual patient data meta-analysis of 10 randomized clinical trials (DAEDALUS study)

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Three-year outcomes of the DKCRUSH-V trial comparing DK crush with provisional stenting for left main bifurcation lesions
15 Oct 2019
DKCRUSH-V showed lower rates of target lesion failure at one year in the DKCRUSH arm, mainly driven by increased rates of target vessel MI. In this paper, the authors report the extended follow-up to three years.

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Transcatheter aortic valve implantation vs. surgical aortic valve replacement for treatment of symptomatic severe aortic stenosis: an updated meta-analysis
22 Oct 2019
Owing to new evidence from randomized controlled trials in low-risk patients with severe aortic stenosis, the authors compared the collective safety and efficacy of TAVI vs. SAVR across the entire spectrum of surgical risk patients...

Reviewer
Ticagrelor with or without aspirin in high-risk patients after PCI
07 Oct 2019
The TWILIGHT trial was designed to test the hypothesis that in patients undergoing PCI who are at high risk for ischemic or hemorrhagic complications and who have completed a 3-month course of DAPT with ticagrelor plus aspirin, continued treatment with ticagrelor monotherapy would be superior to ticagrelor...

Reviewer
Impact of long-term ticagrelor monotherapy following 1-month dual antiplatelet therapy in patients who underwent complex percutaneous coronary intervention: insights from the Global Leaders trial
16 Sep 2019
GLOBAL LEADERS was a randomized, open-label, superiority trial in patients who underwent PCI with a biolimus A9-eluting stent for stable CAD or ACS...

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Cognitive decline before and after incident coronary events
05 Sep 2019

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Same-day discharge after elective percutaneous coronary intervention: Insights from the British Cardiovascular Intervention Society
06 Aug 2019
The aim of this study was to evaluate national temporal trends in same-day discharge (SDD) and compare clinical outcomes with those among patients admitted for overnight stay undergoing elective PCI for stable angina.

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Clinical outcomes of state-of-the-art percutaneous coronary revascularisation in patients with three-vessel disease: two-year follow-up of the SYNTAX II study
10 Jul 2019
The 2-year results of the SYNTAX II study seem to primarily underscore the potential to improve patient outcomes by refining the technique and technology of PCI.

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Procedural volume and outcomes for transcatheter aortic-valve replacement
10 Jul 2019
The aim of the study was to evaluate the relationship between volume of TAVR procedures and 30-day outcomes, to determine the persistence of a volume–outcome association...

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