Apostolos Tzikas
Latest contributions
Paravalvular and defects percutaneous closure
21 May 2025 – From EuroPCR 2025
This session presents percutaneous closure techniques for paravalvular leaks and cardiac defects, highlighting complex cases such as closure in patients with mechanical prostheses, pseudoaneurysms, and post-redo sternotomy challenges. Gain practical knowledge on device selection and procedural strategies for successful leak and defect management.

LAA closure and anthrombotic therapies
21 May 2025 – From EuroPCR 2025
Explore contemporary evidence on left atrial appendage (LAA) closure and associated antithrombotic therapies. This session covers strategies for antithrombotic de-escalation, efficacy and safety in patients with anticoagulation contraindications, breakthrough stroke etiology, and anatomical considerations in high-risk atrial fibrillation patients undergoing ablation.

Broadening OPTIONs for LAA closure: innovations and outcomes
20 May 2025 – From EuroPCR 2025
Explore the latest insights into LAA closure from EuroPCR 2025. This session highlights results from the OPTION trial—the largest RCT comparing LAAC (with Watchman FLX) to DOAC therapy in AF patients undergoing ablation. The findings? Comparable stroke prevention at 3 years, with a 56 % reduction...
