David Messika-Zeitoun
Latest contributions
Pills and pumps: targeting heart failure before and after surgical and transcatheter valve interventions
18 Nov 2025 – From PCR London Valves 2025
This session examines the integrated role of heart failure therapies in the peri- and post-procedural management of patients undergoing surgical and transcatheter valve interventions. It reviews current and emerging clinical trial data, discusses identifying high-risk patients, and explores advanced modalities such as cardiac resynchronization and circulatory...
Complications of mitral TEER
18 Nov 2025 – From PCR London Valves 2025
This session addresses complications associated with mitral transcatheter edge-to-edge repair (TEER), showcasing innovative bailout methods such as snare-assisted retrieval of undeployed devices, managing leaflet perforations with latest-generation devices, cases of valve-adjacent tears, mechanical support considerations when pumps fail, and the clinical impact of iatrogenic fossa ovalis...
Heart Team management of complex valve disease
17 Nov 2025 – From PCR London Valves 2025
Explore the dynamics of managing complex valve disease within a multidisciplinary Heart Team framework. This session discusses strategies for building and sustaining high-functioning teams, integrating multimodality imaging, clinical risk assessment, AI tools, and patient preferences into decision-making, alongside effective communication methods to support collaborative care.
Featured research: innovations, safety and evolving pathways in modern TAVI care
16 Nov 2025 – From PCR London Valves 2025
This session addresses contemporary challenges in TAVI, including management of acute valve syndrome through service innovations and the application of Valvosoft non-invasive ultrasound therapy in severe aortic stenosis. It also explores complications such as infective endocarditis post-TAVI, evaluates the feasibility of same-day discharge protocols, and assesses...
TRIGISTRY: Advancing real-world understanding of tricuspid valve disease
07 Nov 2025
Edoardo Zancanaro interviews Julien Dreyfus and David Messika-Zeitoun about TRIGISTRY, an international registry that builds on the TRI-SCORE — now part of the 2025 ESC guidelines. The study confirms that early referral and optimal reduction of tricuspid regurgitation are key to improving outcomes. The team now...
MITRACURE: From results to next steps
Edoardo Zancanaro interviews Julien Dreyfus & David Messika-Zeitoun about the MITRACURE registry, a large international initiative aimed at capturing real-world data on patients with mitral regurgitation referred for surgery. in 2019. The study shows outcomes differ from expert centers, with higher mortality and lower repair rates, especially...
