Isaac George
Latest contributions
TAVI in challenging annular anatomy
17 Nov 2025 – From PCR London Valves 2025
This session addresses the complexities of performing TAVI in challenging annular anatomies. It features case studies such as TAVI-in-TAVI in a patient with Morquio syndrome, strategies for managing severe annular calcification including calcium cracking techniques, and the use of large-diameter Myval valves for very large annuli...
Emergency transcatheter valve interventions: alternative therapy or bridge to surgery?
16 Nov 2025 – From PCR London Valves 2025
This session offers a compelling case-based exploration of emergency transcatheter valve interventions, demonstrating their potential as life-saving alternatives or bridges to surgery in high-risk patients. Through detailed clinical scenarios including cardiogenic shock, acute papillary muscle rupture, and severe aortic regurgitation from infective endocarditis, participants gain practical...
Tricuspid hotline: new devices
22 May 2025 – From EuroPCR 2025
Discover cutting-edge developments in transcatheter tricuspid valve replacement with new device technologies. Review first-in-human trials, early outcomes from multicenter studies, and innovative designs that promise to advance tricuspid regurgitation treatment.
Stroke prevention - featured cases
26 Nov 2024 – From PCR London Valves 2024
Dive into this session featuring selected clinical cases from PCR London Valves 2024, focusing on the use of various stroke prevention strategies during structural heart interventions. Explore techniques such as snaring-assisted TAVR under cerebral embolic protection, single-side access for cerebral embolic protection devices, and the integration...
TAV-in-SAV for surgical bioprosthetic valve failure
26 Nov 2024 – From PCR London Valves 2024
Dive into the intricacies of TAV-in-SAV procedures for failed surgical bioprosthetic valves. Gain a comprehensive understanding of the key information needed to evaluate a failed surgical bioprosthesis before considering a valve-in-valve intervention. Learn strategies to avoid high gradients and patient-prosthesis mismatch, and explore the clinical relevance...
Valve in valve - TAVI in SAV - Part 1
20 Nov 2023 – From PCR London Valves 2023
Explore innovative approaches in TAVI in SAV with this selection of cases: learn how to manage a degenerated surgical valve using a novel transcatheter heart valve, navigate low-contrast valve-in-valve scenarios in early bioprosthesis failure, witness the adaptability of TAVI valve-in-valve in a severely tortuous and horizontal...
Transcatheter mitral valve replacement - The wait will be worth it
20 Nov 2023 – From PCR London Valves 2023
Reflect on the past decade of Transcatheter Mitral Valve Replacement (TMVR) to uncover technical and clinical challenges and the lessons they've taught. Explore innovative technologies addressing persistent issues, offering solutions and anticipated timelines. Additionally, delve into the present and future trial designs, exploring the evidence required for...
TAVI failure - Mechanisms and management
19 Nov 2023 – From PCR London Valves 2023
Explore various cases that focus on TAVI failure, including the effects of the mechanism of TAVR failure on outcomes after re-intervention, the prognostic impact of patient-prosthesis mismatch and paravalvular leak following TAVI, issues related to bioprosthetic valve dysfunction and much more!
