Robert Byrne

Robert Byrne

Interventional cardiologist / Cardiologist
Mater Private - Dublin, Ireland

Latest contributions

Large thrombus burden management in a young patient with inferior STEMI and multivessel disease

08 Oct 2025

A 51-year-old man with an inferior STEMI and multivessel disease was found to have a thrombotic sub-occlusion in the mid RCA. Angiography also revealed significant disease in the LAD. How would you manage this case?

Antonio Landi

Author

Antonio Landi
Andrea Milzi

Author

Andrea Milzi
Marco Valgimigli

Author

Marco Valgimigli

The PCR Textbook

08 Jul 2025

The PCR Textbook covers the length and breadth of percutaneous cardiovascular interventional practice, in particular diagnostic and therapeutic areas.

Is DCB a new valid option for coronary revascularisation?

22 May 2025 – From EuroPCR 2025

This session provides an in-depth evaluation of drug-coated balloons (DCB) as a valid option for coronary revascularisation. Topics include two-year follow-up comparisons between paclitaxel and sirolimus-coated balloons, clinical outcomes after bailout stenting post-DCB angioplasty, meta-analyses contrasting DCB and DES for large native coronary artery disease, and...

Is DCB a new valid option for coronary revascularisation?

From evidence to practice: solving complex cases with EuroIntervention

22 May 2025 – From EuroPCR 2025

Translate evidence into clinical practice with this session focusing on complex case analyses supported by EuroIntervention resources. Experience detailed presentations of challenging PCI, intracoronary imaging, coronary physiology, and TAVI cases, each followed by evidence-based solutions provided through EuroIntervention. Enhance your decision-making skills by integrating guidelines and...

From evidence to practice: solving complex cases with EuroIntervention

The PCR-EAPCI Textbook is pleased to announce a new Editor-in-Chief!

22 May 2025

A formal handover took place on Wednesday, 21 May, in Paris during EuroPCR 2025, marking the transition from Stephan Windecker, former Editor-in-Chief, to Robert Byrne, who now assumes the role as the newly appointed Editor-in-Chief of this leading educational resource for interventional cardiologists.

DCB after REC-CAGEFREE 1 - Vulnerable plaque PCI after PREVENT

21 May 2025 – From EuroPCR 2025

Reflect on the impact of recent trials REC-CAGEFREE 1 and PREVENT on the use of drug-coated balloons (DCB) and preventive PCI for vulnerable plaque. This session includes case discussions highlighting DCB applications and insights from cutting-edge clinical studies.

DCB after REC-CAGEFREE 1 - Vulnerable plaque PCI after PREVENT

Current DCB practice: from lesion preparation to follow-up

21 May 2025 – From EuroPCR 2025

Explore current best practices in drug-coated balloon (DCB) angioplasty from lesion preparation to follow-up. This session discusses common indications, management of dissections and complications, and shares practical tips and case examples, equipping clinicians with comprehensive knowledge to optimize DCB use in contemporary PCI.

Current DCB practice: from lesion preparation to follow-up

What is the latest in DCB practice?

21 May 2025 – From EuroPCR 2025

Robert Byrne and Bruno Scheller explore the current role of drug-coated balloon (DCB) angioplasty nearly two decades after its initial clinical use. This discussion covers when and how to apply DCB angioplasty effectively in everyday practice, focusing on lesion preparation for de novo coronary disease and...

What is the latest in DCB practice?

Acute coronary syndromes: summary of the 2023 ESC Guidelines - a new chapter in The PCR Textbook

18 Jun 2024 – From EuroPCR 2024

Join Piera Capranzano and Robert Byrne in this video to delve into the new chapter of The PCR Textbook on the 2023 ESC guidelines for acute coronary syndromes. This chapter highlights key points for interventional cardiologists, focusing on invasive management, antiplatelet and anti-thrombotic therapy, and revascularization...

Acute coronary syndromes: summary of the 2023 ESC Guidelines - a new chapter inThe PCR Textbook

PCI of calcified lesions

16 May 2024 – From EuroPCR 2024

This session delves into the treatment of calcified lesions, providing a comprehensive overview of contemporary tools and techniques for optimal plaque modification. Attendees will learn through a series of case presentations, where experts dissect challenging cases involving severe coronary calcification, including in the left main trunk....

PCI of calcified lesions

Mastering the future of PCI with drug-coated balloons

16 May 2024 – From EuroPCR 2024

Join this session dedicated to drug-coated balloons (DCB) to delve into the evolution of angioplasty with DCBs in the U.S. Learn about the established standard of care, balancing efficacy and safety in treating in-stent restenosis (ISR). Gain insights into the fundamental principles of angioplasty with DCB...

Mastering the future of PCI with drug-coated balloons

Imaging-guided PCI for stent failure - LIVE case

16 May 2024 – From EuroPCR 2024

An 86-year-old male with PAD, a stroke in 2007, and a history of LAD PCI in 2006, presented with unstable angina due to LAD stent restenosis involving D1 and D2, with preserved LV function.
Guided by OCT, the operators performed stenosis preparation using IVL, treated the distal...

Imaging-guided PCI for stent failure - LIVE case

A new horizon in IVUS-guided PCI of calcified stenoses with artificial intelligence

15 May 2024 – From EuroPCR 2024

In this session, observe the enhanced user-friendliness of IVUS-guided complex PCI with improved AI algorithms, recognize the importance of combining experience with advanced knowledge of tools and techniques for optimal PCI outcomes in heavily calcified stenoses, and understand how tailoring drug-eluting devices for calcified lesions can...

A new horizon in IVUS-guided PCI of calcified stenoses with artificial intelligence

Major Late-Breaking Trials from EuroPCR 2024

15 May 2024 – From EuroPCR 2024

This session presents the latest results from major late-breaking trials presented at EuroPCR 2024. It covers a one-month DAPT followed by 5-month ticagrelor monotherapy in acute coronary syndromes with DCB, the first TAVI vs. SAVR randomised trial in younger low-risk patients with severe tricuspid or bicuspid...

Major Late-Breaking Trials from EuroPCR 2024

Has the 2023 ESC-EACTS guideline review on left main changed my practice?

15 May 2024 – From EuroPCR 2024

Watch this session if you wish to learn why the 2019 guidelines were revised, how to apply the updated recommendations in clinical settings through case examples, and the criteria for selecting patients with left main stenosis for PCI versus CABG.
The session includes detailed presentations on...

Has the 2023 ESC-EACTS guideline review on left main changed my practice

Hotline: new coronary devices (DES, BRS, DCB)

14 May 2024 – From EuroPCR 2024

This hotline session provides a comprehensive overview of the latest clinical data on new coronary devices, including bioresorbable scaffolds, drug-coated balloons, and drug-eluting stents. Participants will learn about the outcomes of various randomized trials and registry studies, examining the performance of these innovative technologies in different...

Hotline: New Coronary Devices Unveiled

When to use drug coated balloons in de novo lesions?

What areas are most subject to drug-coated balloon angioplasty in de novo lesions? Fernando Alfonso and Robert Byrne provide some answers in this interview, in which they list the scenarios in which this technology appears attractive.

Small vessel disease, diffuse disease, STEMI, side-branches and patients at high-bleeding risk are...

When to use drug coated balloons in de novo lesions?

Current indications for DCB in de novo lesions

18 May 2023 – From EuroPCR 2023

If you are interested in learning more about drug-coated balloon angioplasty in de novo disease, don't miss this informative session, which incorporates real-life cases. The session begins with a comprehensive review of the top five papers published in the past year, focusing on this topic. Additionally,...

Current indications for DCB in de novo lesions

Innovations in coronary disease, diagnosis and treatment

18 May 2023 – From EuroPCR 2023

Join the panelists as they present a series of innovations in coronary disease. Amplify your insight into this vital topic and uncover an array of novelties in diagnosis and treatment.

Innovations in coronary disease, diagnosis and treatment

EuroPCR 2023 Hotlines/Late-Breaking Trials: focus on stent technology

17 May 2023 – From EuroPCR 2023

If you would like to learn more about the latest findings on stent techhnology, check-out this session in which speakers reviewed a series of recent trials, among them: 12-month primary endpoint outcomes of the BIOADAPTOR-RCT; Final 5-year results from the blinded ABSORB IV trial ; BIOMAG-I:...

Late breaking trials on stent technology

Role of physiology during PCI

19 May 2022 – From EuroPCR 2022

Follow, LIVE from Barcelona, Spain, the case of a 61-year-old female patient, former smoker, diabetic, suffering from hypercholesterolemia, dyspnea, and chest pain on exertion for years, admitted for NYHA III heart failure, and discover the importance of physiology and intracoronary imaging in daily practice.

Role of physiology during PCI

PCR Innovators Day - Follow-up and technology updates

19 May 2022 – From EuroPCR 2022

In this EuroPCR 2022 session, find out more about how mastering heart failure treatment by empowering physicians and patients, discover a novel approach for fluid removal, an adjustable interatrial shunt system, and much more!

PCR Innovators Day - Follow-up and technology updates

TAVI in complex scenario

18 May 2022 – From EuroPCR 2022

Watch these videos to discover a selection of the most complex and high-risk TAVI cases presented during EuroPCR 2022: augmented reality for procedural planning in complex clinical scenario, mechanical circulatory support during high-risk TAVI in the COVID-19 era, TTE and IVL-assisted zero-contrast transfemoral TAVR, and more!

TAVI in complex scenario

EuroPCR 2022 Hotlines / Late-Breaking Trials in coronary stenting: SORT OUT VIII, ROLEX, FANTOM II, and more!

18 May 2022 – From EuroPCR 2022

Find out more about various studies & registries in coronary stenting! FANTOM II trial, five-year follow-up in the SORT OUT VIII trial, impact of side branch disease pattern on outcome following left main PCI, intravascular imaging vs. angiography-guided PCI in high bleeding risk patients, safety and...

EuroPCR 2022 Hotlines / Late-Breaking Trials in coronary stenting: SORT OUT VIII, ROLEX, FANTOM II, and more!

Cre8 EVO: the "sweetest advancement" that a diabetic patient is waiting for

18 May 2022 – From EuroPCR 2022

Thanks to a mix between cases and live lectures and discussions, this EuroPCR 2022 session will enable you to review the challenges of a PCI and the one-year results of the SUGAR RCT in diabetes mellitus patients, and to understand how to maximise PCI outcomes, especially by using Cre8 EVO...

Cre8 EVO: the 'sweetest advancement' that a diabetic patient is waiting for

The current role of paclitaxel DCB in PCI

18 May 2022 – From EuroPCR 2022

Thanks to the different interventions of this EuroPCR 2022 session, understand the role of paclitaxel DCB in modern era interventional cardiology, the differences, and advantages versus DES, the role of blended therapies in CLS, and learn how to correctly prepare the lesion and obtain the best from this technology on...

The current role of paclitaxel DCB in PCI

EuroIntervention - Most discussed papers of the year

19 May 2021 – From EuroPCR 2021

Watch this session if you want to know the top 3 most discussed papers of the year which concern management of myocardial revascularisation failure, the impact of COVID-19 pandemic on interventional cardiology practice and Ischaemia witch non-obstructive coronary arteries.

This session was originally presented during EuroPCR 2021.

EuroIntervention - Most discussed papers of the year

Where deliverability matters: challenging cases requiring a low profile

18 May 2021 – From EuroPCR 2021

Watch this session presented by Robert Byrne, Ralph Toelg, Stefano Galli, Farrel Hellig and Jack Tan in order to participate in interactive reviews of interesting DES, DCB and covered stent cases and outcomes, to assess where ultrathin DES, DCB and covered stent provide a clinical benefit, and to...

Where deliverability matters: challenging cases requiring a low profile

The year in intervention: essential publications from EuroIntervention and the European Heart Journal

27 Jun 2020 – From PCR e-Course 2020

Watch this video to find out what were the most essential, impactful and influential papers published in EuroIntervention and the European Heart Journal over the past year, and learn more about the academic versus social impact of citations.

The year in intervention: essential publications from EuroIntervention and the European Heart Journal

How to understand the ISCHEMIA trial?

27 Jun 2020 – From PCR e-Course 2020

Watch this session if you want to get a better understanding of what the ISCHEMIA trial is about and what it is not about, and to make up your own opimind on the strength of the ISCHEMIA conclusions based on its methodology and results.

This session was...

How to understand the ISCHEMIA trial?