Tim Van De Hoef
Latest contributions
Refactory angina and coronary sinus reducer, from established applications to future outlooks
21 May 2026 – From EuroPCR 2026
In this discussion, Tim van de Hoef and Tommaso Gori explore the evolving definition of refractory angina, extending beyond obstructive disease to include non-obstructive and microvascular conditions. They highlight the challenges of recognition, driven by variability in symptoms, diagnostic approaches, and clinical practices, and stress that...
INOCA in patients with coronary artery disease
21 May 2026 – From EuroPCR 2026
This session focuses on ischaemia with non-obstructive coronary arteries (INOCA) in patients with coronary artery disease. It raises awareness of common clinical presentations, emphasizes accurate diagnosis through functional coronary testing, and discusses how tailored treatment strategies can improve patient outcomes in this frequently under-recognized condition.
Diagnosis and management of INOCA and ANOCA
21 May 2026 – From EuroPCR 2026
This session focuses on the diagnosis and management of ischemia and angina with non-obstructive coronary arteries (INOCA and ANOCA). It presents safety data from coronary function testing, patient outcomes after comprehensive ischemia assessment, and endotype-specific treatment effects. Further topics include coronary sinus reducer therapy, the impact...
Early evidence from a next generation coronary sinus reducer for the treatment of coronary microvascular dysfunction
20 May 2026 – From EuroPCR 2026
This EuroPCR 2026 session presents early clinical experience with a next-generation self-expanding nitinol coronary sinus reducer for patients with coronary microvascular dysfunction. It reviews practical aspects of device implantation and discusses initial findings from the SERRA I feasibility study, providing insight into this emerging therapeutic approach....
Assessment of vasomotor coronary disorders in the cathlab
20 May 2026 – From EuroPCR 2026
This session focuses on the invasive assessment of vasomotor coronary disorders within the catheterization laboratory. It reviews clinical profiles, endothelial function evaluation using acetylcholine and advanced hemodynamic methods, coronary volume analysis, and refined classification of coronary spasm, enhancing diagnostic accuracy in patients with suspected ischemia and...
Once you find microvascular disease, what do you actually do?
18 May 2026 – From EuroPCR 2026
Addressing coronary microvascular disease requires a comprehensive understanding of current medical therapies and emerging interventions. This session reviews state-of-the-art pharmacological treatments, elucidates the mechanisms and clinical data surrounding the coronary sinus reducer (CSR), and offers critical discussion on its therapeutic role in microvascular dysfunction.
Coronary physiology: FFR and beyond
22 May 2025 – From EuroPCR 2025
Advance your understanding of coronary physiology with a focus on fractional flow reserve (FFR) and beyond. This session covers randomized trials comparing physiology-guided treatment to standard care in ANOCA, graft patency related to quantitative flow ratio, impacts of microvascular dysfunction on patient outcomes, and prognostic value...
How a new generation of coronary sinus reducer can significantly expand treatment options for patients with coronary microvascular dysfunction
21 May 2025 – From EuroPCR 2025
Discover the latest on managing coronary microvascular dysfunction (CMD) with insights from EuroPCR 2025. This session explores how physiology testing helps identify CMD endotypes in the cathlab and highlights the limitations of ETT for patients experiencing angina or dyspnea at rest. Learn about the A-FLUX coronary...
Full physiology: why and how to assess beyond coronary epicardial disease
20 May 2025 – From EuroPCR 2025
Understanding full coronary physiology is key to improving patient care. This EuroPCR 2025 session unpacks the concept and shows how to apply it easily in everyday clinical settings. Explore the latest ESC guidelines for managing patients with angina and no obstructive coronary artery disease (ANOCA), supported...
ANOCA/INOCA: when angiography is not enough to reach a diagnosis
16 May 2024 – From EuroPCR 2024
This session provides practical knowledge on the diagnosis and management of patients with ANOCA/INOCA (Angina with Non-Obstructive Coronary Arteries/Ischemia with Non-Obstructive Coronary Arteries). It covers the evaluation of microvascular and vasomotor disorders in patients with non-obstructive coronary arteries, and the causes and management of patients with...