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Clinical and echocardiographic outcomes among the first 500 patients treated with a dedicated transcatheter aortic valve for pure aortic regurgitation in the Align-AR clinical trial

31 Mar 2025

Jonathan Curio interviews Raj Makkar about the results of the Align-AR trial which he presented during the ACC.25 in Chicago.

Jonathan Curio

Author

Jonathan Curio
Raj Makkar

Author

Raj Makkar
Clinical and echocardiographic outcomes among the first 500 patients treated with a dedicated transcatheter aortic valve for pure aortic regurgitation in the Align-AR clinical trial

PCR London Valves 2022 was an incredible success, with over 3,500 participants!

View great snapshots, opening and closing videos, key facts and figures on valvular community!
Best of PCR London Valves 2022

The 2023 top Japanese abstracts

18 Feb 2023 – From PCR Tokyo Valves 2023

Explore the cutting-edge research showcased in the top Japenese abstracts of PCR Tokyo Valves 2023. Uncover profound insights, including a detailed examination of three-year outcomes in 500 patients treated with MitraClip, a comparative analysis of outcomes between COMBO therapy and transcatheter edge-to-edge repair for severe mitral...

Triluminate trial: deep dive into the outcomes

In this video, members of the PCR Tricuspid Focus Group Nicole Karam and Ralph Stephan von Bardeleben talk with David Adams and Paul Sorajja about the first landmark trial in the field of tricuspid valve disease, Triluminate. Together they discuss the results presented during the ACC.23/WCC...

Triluminate trial: deep dive into the outcomes

Hotline - ACURATE neo2 under-expansion in the ACURATE IDE study: a post-hoc analysis

21 May 2025 – From EuroPCR 2025

Howard Herrmann and Raj Makkar discuss a sub-study of the ACURATE IDE trial, which examined valve under-expansion detected by fluoroscopy. Among 1,500 patients with aortic stenosis, 22 % of ACURATE neo2 valves showed under-expansion, often linked to heavy valve calcification.

Patients with under-expanded valves faced higher risks...

ACURATE neo2 under-expansion in the ACURATE IDE study: a post-hoc analysis

Tricuspid TEER: learnings from the 2-year outcomes of TRILUMINATE Pivotal trial & bRIGHT study

20 May 2025 – From EuroPCR 2025

At EuroPCR 2025, Marianna Adamo and Ralph Stephan von Bardeleben discussed the latest findings on tricuspid valve repair using transcatheter edge-to-edge repair (TEER).

The 2-year results from the TRILUMINATE Pivotal trial showed a significant reduction in tricuspid regurgitation, lasting improvements in quality of life, and a notable...

Tricuspid TEER: learnings from the 2-year outcomes of TRILUMINATE Pivotal trial & bRIGHT study

EuroPCR 2018 Opening Ceremony and Ethica Awards

22 May 2018 – From EuroPCR 2018

Join J. Fajadet and W. Wijns for the EuroPCR 2018 Opening Ceremony and find out who this year's Ethica Awards winners are!

EuroPCR 2018 Opening Ceremony and Ethica Awards

EuroPCR 2018 Closing Ceremony

25 May 2018 – From EuroPCR 2018

Consult the session video on the Closing Ceremony of EuroPCR 2018 presented by A. Baumbach.

EuroPCR 2018 Closing

Nurses and Allied Professionals Best Abstract and Clinical Case Awards and Closing Ceremony

24 May 2018 – From EuroPCR 2018

Consult this session to see best abstract and clinical case awards for nurses and allied professionals at EuroPCR 2018.

Nurses and Allied Professionals Best Abstract and Clinical Case Awards and Closing Ceremony

EAPCI-PCR Fellows Course - Opening Ceremony

20 May 2019 – From EuroPCR 2019

Consult this session to discover the EAPCI-PCR Fellows Course opening ceremony, introducing EAPCI, EuroPCR, Fellows course, and the EAPCI youngs. 

EAPCI-PCR Fellows Course - Opening Ceremony

Basics - Not boring but crucial

20 May 2019 – From EuroPCR 2019

Consult this session to learn all about the most crucial basics needed to know before starting any coronary interventions, and discover how to practically reduce radiation risk, how to perform safe vascular access, how to perform optimal angiogram, and more!

Basics - Not boring but crucial

Beyond angios - Intravascular understanding of coronary anatomy and function

20 May 2019 – From EuroPCR 2019

Consult this session to learn more about how to apply intravascular diagnostic techniques in daily practice, when and why these modalities are needed, and how to translate imaging/physiological data in decision process of PCI.

Beyond angios - Intravascular understanding of coronary anatomy and function

Bifurcations - Which technique, when, why and how?

20 May 2019 – From EuroPCR 2019

Consult this session to learn more about how to assess bifurcation anatomy as part of procedural planning, and discover a practical step-by-step algorithm for performing bifurcation PCI (provisional T, TAP, Culotte and DK crush).

Bifurcations - Which technique, when, why and how?

Welcome introduction

20 May 2019 – From PCR Innovators Day 2019

Consult this session to watch EuroPCR 2019 welcome introduction, and learn more about what you can expect from PCR Innovators' Day, the unique European forum enabling clinicians, medical experts and innovators to exchange on the latest devices, information technology and e-health.

Welcome introduction

Sticky problems, new solutions

20 May 2019 – From PCR Innovators Day 2019

Consult this session on "Sticky problems, new solutions" to discover the studies and tools developed by Cavis Technologies, Wirecath, CorFlow Therapeutics, Procyrion and GENOSS, and learn more about how to "unstick" from the problems you usually encounter during your practice.

Sticky problems, new

Presentations by the Jon DeHaan Foundation Grant applicants

20 May 2019 – From PCR Innovators Day 2019

Roundtable discussion - Bringing innovation to the healthcare delivery systems: the promise, the need, and the challenges

20 May 2019 – From PCR Innovators Day 2019

Stent - Save A Life! 10th Anniversary Forum - Regional synopsis – Where are we and what are the next steps?

20 May 2019 – From EuroPCR 2019

Consult this session to read about the regional synopsis of Stent - Save a Life, which celebrated its 10th anniversary in 2019, and discover the future perspectives offered by this forum in Europe, Latin America, Africa and Asia.

Stent - Save A Life! 10th Anniversary Forum - Regional synopsis

Complications - What to do when a nightmare comes true

20 May 2019 – From EuroPCR 2019

Consult this session to get practical tips on how life-threatening complications can be managed once they occur, such as proximal and distal coronary perforation, intracoronary lost device, and more!

Complications - What to do when a nightmare comes true

Acute coronary syndrome - How to avoid bleedings and save lives

20 May 2019 – From EuroPCR 2019

Consult this session to learn how to customise antiplatelet therapy, as long with the basics of mechanical circulatory support devices.

Acute coronary syndrome - How to avoid bleedings and save lives
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