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Clinical and echocardiographic outcomes among the first 500 patients treated with a dedicated transcatheter aortic valve for pure aortic regurgitation in the Align-AR clinical trial

31 Mar 2025

Jonathan Curio interviews Raj Makkar about the results of the Align-AR trial which he presented during the ACC.25 in Chicago.

Jonathan Curio

Author

Jonathan Curio
Raj Makkar

Author

Raj Makkar
Clinical and echocardiographic outcomes among the first 500 patients treated with a dedicated transcatheter aortic valve for pure aortic regurgitation in the Align-AR clinical trial

PCR London Valves 2022 was an incredible success, with over 3,500 participants!

View great snapshots, opening and closing videos, key facts and figures on valvular community!
Best of PCR London Valves 2022

The 2023 top Japanese abstracts

18 Feb 2023 – From PCR Tokyo Valves 2023

Explore the cutting-edge research showcased in the top Japenese abstracts of PCR Tokyo Valves 2023. Uncover profound insights, including a detailed examination of three-year outcomes in 500 patients treated with MitraClip, a comparative analysis of outcomes between COMBO therapy and transcatheter edge-to-edge repair for severe mitral...

Triluminate trial: deep dive into the outcomes

In this video, members of the PCR Tricuspid Focus Group Nicole Karam and Ralph Stephan von Bardeleben talk with David Adams and Paul Sorajja about the first landmark trial in the field of tricuspid valve disease, Triluminate. Together they discuss the results presented during the ACC.23/WCC...

Triluminate trial: deep dive into the outcomes

Hotline - ACURATE neo2 under-expansion in the ACURATE IDE study: a post-hoc analysis

21 May 2025 – From EuroPCR 2025

Howard Herrmann and Raj Makkar discuss a sub-study of the ACURATE IDE trial, which examined valve under-expansion detected by fluoroscopy. Among 1,500 patients with aortic stenosis, 22 % of ACURATE neo2 valves showed under-expansion, often linked to heavy valve calcification.

Patients with under-expanded valves faced higher risks...

ACURATE neo2 under-expansion in the ACURATE IDE study: a post-hoc analysis

Tricuspid TEER: learnings from the 2-year outcomes of TRILUMINATE Pivotal trial & bRIGHT study

20 May 2025 – From EuroPCR 2025

At EuroPCR 2025, Marianna Adamo and Ralph Stephan von Bardeleben discussed the latest findings on tricuspid valve repair using transcatheter edge-to-edge repair (TEER).

The 2-year results from the TRILUMINATE Pivotal trial showed a significant reduction in tricuspid regurgitation, lasting improvements in quality of life, and a notable...

Tricuspid TEER: learnings from the 2-year outcomes of TRILUMINATE Pivotal trial & bRIGHT study

AsiaPCR/SingLIVE 2017: Opening Ceremony

19 Jan 2017 – From AsiaPCR/SingLIVE 2017

Consult the Opening ceremony of the AsiaPCR/SingLIVE 2017 course edition, the Chien Foundation Award for outstanding lectureship and lifetime achievement in PCI is awarded to Prof. A. Seth.

Upendra Kaul

Chairperson

Upendra Kaul
AsiaPCR/SingLIVE 2017:

AsiaPCR/SingLIVE 2017: closing Ceremony and Awards

21 Jan 2017 – From AsiaPCR/SingLIVE 2017

Consult the Closing ceremony and awards session from AsiaPCR/SingLIVE 2017, where W. Wijns addresses the subject of what to expect in the field of Interventional Cardiology in 2017, and the speakers present the award winners of this year's best clinical cases namely R. Fukuhara, Japan, W....

Prof. Tian-Hai Koh

Chairperson

Tian Hai Koh
Rosli Mohd Ali

Chairperson

Mohd Ali Rosli
AsiaPCR/SingLIVE 2017:

PCR London Valves 2017 Opening Ceremony - Welcome address

25 Sep 2017 – From PCR London Valves 2017

PCR London Valves 2017

Welcome to Imaging Day

24 Sep 2017 – From PCR London Valves 2017

Welcome and introduction to PCR Innovators Day London

24 Sep 2017 – From PCR Innovators Day 2017

TAVI-related vascular complications

14 Apr 2021 – From EuroPCR 2021

Watch this session to learn more about TAVI migration during valve-in-valve complicated with aortic type A dissection, TAVI and AV leadless pacemaker in a patient with poor vascular access, 14F access site collagen-plug occlusion & trans-radial re-canalization, and more!

EuroPCR 2021 TAVI-related vascular complications

How to tackle calcified lesions for a good outcome

14 Apr 2021 – From EuroPCR 2021

View this session if you're interested in CHIP PCI in ACS with heart failure and high bleeding risk, calcific left main stem restenosis after prior treatment with lithotripsy, calcific restenosis and tight distal narrowing, and much more!

EuroPCR 2021 How to tackle calcified lesions for a good outcome

Transcatheter Valve Implantation or Replacement - Rescue needed: what are the options?

14 Apr 2021 – From EuroPCR 2021

If you wish to learn how to overcome challenges of mitral disease and previous atrial septum closure, how valve re-tensioning can solve hemolysis after TMVI, or how a partially anchored cardioband can detach secondary to system torsion, go and watch this session!

EuroPCR 2021 Rescue needed: what are the options?

Nightmares in the cath lab: prevention is better than cure

14 Apr 2021 – From EuroPCR 2021

In this session, watch a case of emergency high-risk PCI following TAVI in bicuspid anatomy, discover an unconventional treatment for re-stenosis, study how to deal with an emergency LM PCI in a young patient with ACS, and much more!

EuroPCR 2021 Nightmares in the cath lab: prevention is better than cure

A mix of complications in interventional cardiovascular medicine

14 Apr 2021 – From EuroPCR 2021

In this session, you will learn how to adopt the right method when bleeding challenges guidelines, retrieve a fractured driveshaft tip of orbital atherectomy system by micro basket, guide catheter delamination during left main stenting after TAVI, and much more!

EuroPCR 2021 A mix of complications

DK crush or Culotte?

14 Apr 2021 – From EuroPCR 2021

Don't miss this session if you wish to discover how OCT guidance, assisted by IVL, can help in case of DK crush, or how high-risk left main PCI in a patient with severe aortic stenosis can be managed, among others...

EuroPCR 2021 DK crush or Culotte?

Primary PCI: surprise, surprise!

14 Apr 2021 – From EuroPCR 2021

Thanks to this session, view an unusual posterior wall infarction, study a "nightmare" acute coronary syndrome case in the EP Lab, consider STEMI with lots of clots, and more! 

EuroPCR 2021 Primary PCI: surprise, surprise!

Stent dislodgement / Fracture - Part 1

14 Apr 2021 – From EuroPCR 2021

In this session, get the chance to examine an unusual case of deformation of ostial left main stent, learn how to manage stent dislodgement during primary PCI, get familiar with novel handling in stent dislodgement, and more!

EuroPCR 2021 Stent dislodgement / Fracture - Part 1

CTO tools, devices and techniques

14 Apr 2021 – From EuroPCR 2021

The Capture Technique, the intra-coronary Rendezvous Technique, a new technique for proximal cap penetration in a calcified CTO... Watch this session to get all the necessary tools to handle CTO!

EuroPCR 2021 CTO tools, devices and techniques
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