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3185 results

Open design, confident delivery - How a novel LAA closure device provides predictable outcomes in complex anatomical settings

16 Nov 2025 – From PCR London Valves 2025

This session highlights a novel left atrial appendage (LAA) closure device featuring an open-cage design that delivers predictable clinical and procedural outcomes. It discusses the device's advantages in managing complex anatomical variations and presents implantation techniques across diverse anatomies to improve safety and efficacy.

Open design, confident delivery - How a novel LAA closure device provides predictable outcomes in complex anatomical settings

Featured research: advances in TAVI for aortic regurgitation and severe stenosis

16 Nov 2025 – From PCR London Valves 2025

This session delivers an in-depth analysis of innovative research in transcatheter aortic valve implantation (TAVI). It includes pivotal studies such as the LANDMARK trial subanalysis on cardiac damage in severe aortic stenosis patients, long-term efficacy comparisons of balloon- and self-expanding valves, and evaluations of valve performance...

Featured research: advances in TAVI for aortic regurgitation and severe stenosis

The next frontier in LAA closure: innovations and opportunities

17 Nov 2025 – From PCR London Valves 2025

Explore the forefront of left atrial appendage (LAA) closure with this session focusing on the latest innovations and clinical opportunities. Topics include recent data on WATCHMAN FLX PRO and VersaCross Connect systems, workflow strategies to improve procedural efficiency, and discussions on upcoming clinical trials such as...

The next frontier in LAA closure: innovations and opportunities

The index valve matters: optimal index TAVI for a lifetime of possibilities

18 Nov 2025 – From PCR London Valves 2025

Discover how thoughtful index valve selection and implantation techniques can shape the long-term management of patients undergoing TAVI. This PCR London Valves 2025 session highlights treatment considerations for low- and intermediate-risk patients, explores how valve choice affects the feasibility of future interventions, and examines strategies to...

The index valve matters: optimal index TAVI for a lifetime of possibilities

Complex combined interventions

16 Nov 2025 – From PCR London Valves 2025

This session presents complex combined interventions tackling multiple valvular and structural heart challenges simultaneously. It highlights innovative procedural approaches such as the 'super combo' techniques, strategies for managing deteriorative mitral regurgitation post-tricuspid valve replacement, and comprehensive management of torrential tricuspid regurgitation within rheumatic multivalvular disease contexts,...

Challenging tricuspid TEER

16 Nov 2025 – From PCR London Valves 2025

This session focuses on the intricacies of transcatheter tricuspid edge-to-edge repair (TEER) addressing iatrogenic tricuspid regurgitation, failed surgical valve repair, and approaches for patients unsuitable for valve replacement. It also examines the management of multiple clip detachments and the procedural nuances required to navigate complex tricuspid...

Valve selection in urgent TAVI: evidence from small annulus studies - Hotline

16 Nov 2025 – From PCR London Valves 2025

This session presents cutting-edge research comparing self-expanding and balloon-expandable valves in urgent and emergent TAVI settings, with a focus on small aortic annuli. It includes data from the NAVULTRA and LANDMARK trials, featuring novel biomimetic balloon-expandable valves and early feasibility studies that shed light on valve...

Hotline - TAVI - Part 2

New approaches in aortic regurgitation

16 Nov 2025 – From PCR London Valves 2025

Explore new diagnostic and therapeutic approaches for managing aortic regurgitation. This session covers imaging modalities, guideline-directed patient selection, current transcatheter treatment techniques, and emerging TAVI technologies designed specifically for non-calcific aortic valve pathology.

New approaches in aortic regurgitation

Valve interventions in congenital heart disease

16 Nov 2025 – From PCR London Valves 2025

This session presents complex valve interventions in congenital heart disease, highlighting challenging cases such as positional hypoxaemia due to iatrogenic atrial defects, navigating residual shunts after PFO closure, and transcatheter pulmonary valve replacement in native right ventricular outflow tracts without pre-stenting. It also examines an intriguing...

Featured research - Tricuspid valve interventions - Part 2

16 Nov 2025 – From PCR London Valves 2025

This session highlights recent advances in tricuspid valve interventions with a focus on complex clinical scenarios. Topics include percutaneous annuloplasty as a bridge to edge-to-edge repair, long-term outcomes from the TriCLASP study, novel stratification methods to guide intervention, liver stiffness prognostics, right atrial remodeling post-repair, and...

Challenging TAVI

16 Nov 2025 – From PCR London Valves 2025

This session addresses the complexities encountered in transcatheter aortic valve implantation (TAVI) in challenging anatomical settings. It reviews management of bicuspid valves with calcification, horizontal aorta, coronary artery anomalies, and navigation of difficult angles. Case studies illustrate techniques to optimize commissural alignment and strategies to address...

Tricuspid interventions: knowns and unknowns

17 Nov 2025 – From PCR London Valves 2025

Explore the evolving landscape of transcatheter tricuspid valve interventions in this session, which presents the latest evidence from registries and randomized trials. Discussions include the new Euro tricuspid regurgitation risk score, clinical controversies, real-world patient scenarios, and insights into optimal medical therapy and device selection to...

Tricuspid interventions: knowns and unknowns

TAVI: nightmare in the cathlab - Annular perforation, coronary obstruction & balloon rupture

17 Nov 2025 – From PCR London Valves 2025

This session presents critical case analyses of complicated TAVI procedures, highlighting unexpected and severe intra-procedural events such as annular perforation, leaflet modification complications, coronary obstructions, and device failures. It emphasizes prevention strategies, bailout techniques, and acute management to prepare clinicians for handling TAVI-related emergencies effectively.

TAVI: nightmare in the cathlab - Annular perforation, coronary obstruction & balloon rupture

Paravalvular leak closure - Part 2

17 Nov 2025 – From PCR London Valves 2025

This session is dedicated to paravalvular leak (PVL) closure techniques, featuring percutaneous approaches after surgical valve implantation and TAVI complications such as annulus rupture. It includes advanced management using multiple plugs for long-tunnel mitral PVLs, innovative transformation from pop-up to plug strategies, and transapical approaches following...

TAVI Valve-in-Valve: Managing unexpected anatomical challenges

17 Nov 2025 – From PCR London Valves 2025

This session examines valve-in-valve interventions in TAVI, highlighting management of concomitant left main disease, unique case narratives such as "The Highlander story," and the unpredictability inherent in these procedures. It also reviews successful transfemoral TAV-in-SAV interventions in acute heparin-induced thrombocytopenia and addresses treatment of degenerated sutureless...

TAVI Valve-in-Valve: Managing unexpected anatomical challenges

Featured research - Tricuspid valve intervention: latest advanced insights

17 Nov 2025 – From PCR London Valves 2025

This featured research session delves into advanced insights on tricuspid valve interventions, focusing on the significance of right ventricular function and dimension in patient outcomes. It explores prognostic factors such as right ventricular loading mismatch, innovations like the clover technique in Pascal TEER, myocardial work recovery,...

Featured research - Tricuspid valve intervention: latest advanced insights

Valve interventions in grown-up congenital heart disease

17 Nov 2025 – From PCR London Valves 2025

This session presents complex valve interventions in patients with grown-up congenital heart disease, showcasing innovative transcatheter approaches including combined TAVI and pulmonary valve implantation in high-risk patients. Cases highlight management strategies in elderly patients with concomitant conditions such as patent ductus arteriosus and severe left ventricular...

Featured research - TAVI: cutting-edge developments

17 Nov 2025 – From PCR London Valves 2025

This featured research session reviews cutting-edge developments in TAVI, addressing challenges and outcomes in young patients with bicuspid aortic valve stenosis, prognostic significance of concomitant valvular disease, and long-term results of prophylactic chimney stenting and prosthetic valve performance in bicuspid stenosis.

Featured research - TAVI: cutting-edge developments

Paravalvular leaks and VSD percutaneous closure - Recorded cases

17 Nov 2025 – From PCR London Valves 2025

Recorded case 1: A 56-year-old female with a prior mechanical mitral valve replacement (Star GK, 2018), permanent AF, and normal LV function presented with recurrent HF admissions due to paravalvular leaks. She was treated with implantation of multiple plugs via a transseptal approach using a Destination...

Paravalvular leaks and VSD percutaneous closure - Recorded cases

Percutaneous mitral balloon commissurotomy in unusual scenarios

17 Nov 2025 – From PCR London Valves 2025

This session examines percutaneous mitral balloon commissurotomy applied in unusual and challenging scenarios. It covers advanced techniques such as wire-guided Inoue balloon valvuloplasty post annuloplasty, strategies for severe mitral calcification, and innovative simplifications of established methods, emphasizing the ongoing relevance of this procedure in complex mitral...

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