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3136 results

Featured research: innovative solutions for mitral valve repair and replacement

16 Nov 2025 – From PCR London Valves 2025

This featured research session offers a comprehensive exploration of mitral valve interventions, encompassing electrosurgical device removal techniques, transcatheter mitral valve replacement (TMVR) outcomes, and transcatheter edge-to-edge repair (TEER) in complex clinical contexts such as heart transplantation and acute valve syndromes. It further examines pulmonary artery systolic...

Featured research: innovative solutions for mitral valve repair and replacement

TAVI in aortic regurgitation

16 Nov 2025 – From PCR London Valves 2025

This session addresses the challenges and innovations in transcatheter aortic valve implantation (TAVI) for aortic regurgitation. It covers complex clinical scenarios such as severe regurgitation post-endocarditis, alternative access routes complicated by prosthesis embolisation, and the use of dedicated TAVI devices in non-tricuspid valves. The session also...

TAVI-in-TAVI

16 Nov 2025 – From PCR London Valves 2025

This session explores the nuanced field of TAVI-in-TAVI procedures, focusing on valve durability considerations between bovine and porcine valves, strategies for redo TAVI post valve-in-valve, and advanced interventions to secure coronary flow such as inter-valvular stenting. It highlights complex anatomical challenges including aberrant coronary origins and...

Mitral valve-in-valve: high-left ventricular outflow tract obstruction risk

16 Nov 2025 – From PCR London Valves 2025

This session focuses on the management of high-risk left ventricular outflow tract (LVOT) obstruction in mitral valve-in-valve procedures. It discusses innovative approaches such as the tip-to-base LAMPOON procedure to mitigate obstruction risk, techniques for cutting obstructive tissue, and combined strategies involving sentinel-protected submitral aneurysm closure and...

Transcatheter tricuspid valve replacement

16 Nov 2025 – From PCR London Valves 2025

This session reviews contemporary advances in transcatheter tricuspid valve replacement (TTVR). It highlights long-term follow-up data from tricuspid valve-in-valve cases, introduces the novel Vdyne valve device for tricuspid regurgitation, and discusses timing considerations for interventions following surgical aortic valve replacement. Additionally, it evaluates the role of...

Curious mitral and tricuspid scenarios

16 Nov 2025 – From PCR London Valves 2025

This session presents a series of challenging and unusual clinical scenarios involving mitral and tricuspid valve disease. Topics include management of acute primary mitral regurgitation in high-surgical-risk patients, technical challenges in transcatheter mitral valve replacement (TMVR), and complex cases where cardiac rhythm disturbances interplay with valvular...

Late-Breaking Trials in transcatheter mitral, tricuspid and aortic interventions - Part 1

16 Nov 2025 – From PCR London Valves 2025

This session presents pivotal late-breaking trials in transcatheter mitral and aortic valve interventions. Explore one-year outcomes from the AltaValve early feasibility study featuring atrial fixation TMVR, interim results from the TARGET study assessing Cardiovalve for tricuspid regurgitation, five-year data on transapical TMVR, and outcomes of TAVI...

The Top Late-Breaking Trials - Part 1

Mastering simple and complex LAA closure: a step-by-step case-based approach

16 Nov 2025 – From PCR London Valves 2025

This case-based session offers a comprehensive approach to mastering left atrial appendage (LAA) closure, emphasizing the critical role of imaging from pre-procedural planning through execution. It covers patient selection, procedural strategies from experienced operators, device selection tailored to anatomy, and nuanced decision-making during challenging device releases...

Mastering simple and complex LAA closure: a step-by-step case-based approach

Featured research: advances in TAVI for aortic regurgitation and severe stenosis

16 Nov 2025 – From PCR London Valves 2025

This session delivers an in-depth analysis of innovative research in transcatheter aortic valve implantation (TAVI). It includes pivotal studies such as the LANDMARK trial subanalysis on cardiac damage in severe aortic stenosis patients, long-term efficacy comparisons of balloon- and self-expanding valves, and evaluations of valve performance...

Featured research: advances in TAVI for aortic regurgitation and severe stenosis

Beyond TAVI

16 Nov 2025 – From PCR London Valves 2025

This session offers a glimpse into cutting-edge structural heart interventions beyond TAVI. It introduces novel devices in early development stages targeting aortic valve stenosis and leaflet modification, discusses strategies to facilitate or defer TAVI, and provides opportunities for engagement with early-stage start-up partners innovating in structural...

Complex valve-in-valve leaflet modification - LIVE Case

17 Nov 2025 – From PCR London Valves 2025

Watch this LIVE case followed by a recorded case, regarding a 79-year-old male with permanent AF and a history of surgical aortic valve replacement in 2010 (Magna Ease 25) who presented with symptomatic bioprosthetic valve stenosis, normal LV function, and no CAD. A Sapien 3 Ultra...

Complex valve-in-valve leaflet modification - LIVE Case

Transcatheter mitral valve-in-valve: alternative strategy for optimal alignment

17 Nov 2025 – From PCR London Valves 2025

This session focuses on transcatheter mitral valve-in-valve procedures, emphasizing alternative strategies for optimal alignment and lifetime management planning. It delves into engineering the landing zone for challenging anatomies, the integration of the LAMPOON procedure in TMVR valve-in-valve cases, and addresses complexities arising from mitral annular calcification.

Transcatheter mitral valve-in-valve: alternative strategy for optimal alignment

Nightmare mitral interventions

16 Nov 2025 – From PCR London Valves 2025

This session presents complex mitral valve intervention cases highlighting procedural challenges and innovative solutions. It includes management of embolised transcatheter mitral valve replacements (TMVR), bailout redo transcatheter edge-to-edge repair (TEER), complications such as acute hypoxia and atrial wall perforations, and the application of TAVI skills in...

TAVI Valve-in-Valve: Managing unexpected anatomical challenges

17 Nov 2025 – From PCR London Valves 2025

This session examines valve-in-valve interventions in TAVI, highlighting management of concomitant left main disease, unique case narratives such as "The Highlander story," and the unpredictability inherent in these procedures. It also reviews successful transfemoral TAV-in-SAV interventions in acute heparin-induced thrombocytopenia and addresses treatment of degenerated sutureless...

TAVI Valve-in-Valve: Managing unexpected anatomical challenges

Tricuspid valve interventions in complex scenarios

16 Nov 2025 – From PCR London Valves 2025

This session explores tricuspid valve interventions in complex clinical scenarios, emphasizing emerging techniques such as electrosurgical laceration to enable TTVR, emergency TEER for papillary muscle rupture, and expanded options for difficult valve disease. It also addresses procedural challenges when conventional implantation maneuvers fail, transcatheter alternatives for...

Paravalvular leak closure - Part 2

17 Nov 2025 – From PCR London Valves 2025

This session is dedicated to paravalvular leak (PVL) closure techniques, featuring percutaneous approaches after surgical valve implantation and TAVI complications such as annulus rupture. It includes advanced management using multiple plugs for long-tunnel mitral PVLs, innovative transformation from pop-up to plug strategies, and transapical approaches following...

Transcatheter solutions for rare complications

16 Nov 2025 – From PCR London Valves 2025

This session focuses on transcatheter solutions for rare and unexpected cardiovascular complications. It features percutaneous closure techniques for ascending aortic pseudoaneurysms, approaches to challenging procedural detachment issues, comprehensive valvular disease management, and complex repairs for coexisting severe aortic coarctation and stenosis, underscoring adaptive interventional strategies for...

TAVI for pure aortic regurgitation: different animal, different challenges, different approaches

17 Nov 2025 – From PCR London Valves 2025

This session delves into the unique anatomical and pathophysiological challenges posed by pure aortic regurgitation and their impact on treatment strategies. It reviews clinical outcomes with established and new transcatheter devices, and presents emerging technologies that promise to advance therapeutic options for this distinct patient population.

TAVI for pure aortic regurgitation: different animal, different challenges, different approaches

From diagnosis to device: decision-making and planning for mitral valve interventions

17 Nov 2025 – From PCR London Valves 2025

This session offers a comprehensive overview of decision-making and procedural planning for transcatheter mitral valve interventions. It emphasizes patient-specific factors, advanced imaging for valve morphology assessment, device selection, and the integration of emerging technologies to tailor optimal treatment strategies for mitral valve disease.

From diagnosis to device: decision-making and planning for mitral valve interventions

Early Career Research Award Final

17 Nov 2025 – From PCR London Valves 2025

Highlighting pioneering research in structural heart interventions, this session presents studies on the impact of transcatheter tricuspid valve replacement (TTVR) on left ventricular geometry and function, myocardial remodeling in aortic stenosis, physiological responses after mitral and tricuspid edge-to-edge repairs, advancing the understanding of device effects on...

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