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Challenging cases from the East

10 Dec 2025 – From GulfPCR-GIM 2025

This session from Eastern cardiology centers addresses complex interventional challenges including recurrent left internal mammary artery (LIMA) failure, management of transcatheter aortic valve implantation (TAVI) complications, and treatment of heavily calcified coronary lesions. Through detailed case presentations and key learnings, it offers valuable insights into successful...

Challenging cases from the East

TAVI in small annulus - LIVE Case

11 Dec 2025 – From GulfPCR-GIM 2025

A 65-year-old female with obesity, diabetes mellitus, a history of stroke, atrial fibrillation, and RBBB on ECG, presented with symptomatic aortic stenosis and two-vessel coronary disease (OM and LAD, QFR: 0.70). Echocardiography and CT showed normal LV function (55%), a small annulus (370 mm²), and a...

TAVI in small annulus - LIVE Case

Iatrogenic atrial septum defect closure: a necessary procedure?

18 Nov 2025 – From PCR London Valves 2025

This session addresses the clinical considerations surrounding iatrogenic atrial septal defects (ASDs) resulting from transseptal procedures. It covers prevention of residual defects, diagnostic evaluation, criteria for closure, procedural timing, and management strategies for related complications, supported by illustrative clinical cases demonstrating decision-making nuances.

TAVI complications - Part 5

18 Nov 2025 – From PCR London Valves 2025

This session highlights acute and urgent complications following TAVI implantation, including myocardial infarction, cardiac arrest, and challenging catheterization scenarios. It provides detailed case analyses illustrating the limits of TAVI procedures and the critical importance of prompt recognition and intervention in adverse events, enhancing clinician preparedness for...

Getting ready for tricuspid TEER: key steps in building a successful programme

14 Feb 2026 – From PCR Tokyo Valves 2026

Prepare to establish a successful tricuspid TEER programme by understanding essential components such as systematic echocardiographic and clinical assessments for patient selection, procedural fundamentals, and programme development supported by clinical evidence.

Getting ready for tricuspid TEER: key steps in building a successful programme

Patient selection for tricuspid TEER in 2026

14 Feb 2026 – From PCR Tokyo Valves 2026

This session focuses on optimizing patient selection for tricuspid transcatheter edge-to-edge repair (TEER) in 2026. It integrates anatomical, haemodynamic, and clinical criteria to identify ideal candidates, explores evolving treatment boundaries between TEER, transcatheter tricuspid valve replacement (TTVR), and medical management, and applies evidence from key trials...

Patient selection for tricuspid TEER in 2026

Artificially synthesized optical coherence tomography images based on intravascular ultrasound-virtual histology examination of diseased coronary artery

05 May 2021

Intravascular imaging is a cornerstone of invasive management of coronary disease, requiring specialized training to interpret either IVUS or OCT. AI can facilitate interpretation by non-specialists in real time.

AI-generated synthetic OCT

Transcatheter aortic valve replacement in small aortic annuli: Results from the FRANCE-TAVI registry

17 Sep 2022

Mirvat Alasnag provides her take on the outcomes of small annuli sub-study from the FRANCE-TAVI Registry which included 1,195 patients. This trial was presented by Walid Ben-Ali at TCT 2022.

Dr. Mirvat Alasnag

Author

Mirvat Alasnag
Transcatheter aortic valve replacement in small aortic annuli: Results from the FRANCE-TAVI registry

BRIGHT-4 – Bivalirudin plus a high-dose infusion versus heparin monotherapy in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: a randomised trial

07 Nov 2022

Nicola Ryan provides her take on the BRIGHT-4 study, which was presented during AHA 2022 in Chicago, & simultaneously published in the Lancet.

This study was a randomised control trial designed to assess if bivalirudin plus a high dose infusion for 2-4 hours post PPCI was superior to unfractionated...

Nicola Ryan

Author

Nicola Ryan
BRIGHT-4 – Bivalirudin plus a high-dose infusion versus heparin monotherapy in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: a randomised trial

ENVISAGE-TAVI AF: edoxaban vs. vitamin K antagonists after TAVI in patients with atrial fibrillation

31 Aug 2021

Following the Hot Line session of the ESC Congress 2021 presented by George Dangas (New-York, USA), Daniele Giacoppo offers us a condensed version of this study.

Daniele Giacoppo

Author

Daniele Giacoppo
ENVISAGE-TAVI AF: edoxaban vs. vitamin K antagonists after TAVI in patients with atrial fibrillation

Long-term beta-blocker treatment after acute myocardial infarction and preserved left ventricular ejection fraction: The REDUCE-AMI Trial

07 Apr 2024

REDUCE-AMI is a multicentre, registry-based, prospective open-label parallel-group randomised clinical trial evaluating the benefit of beta-blocker treatment in patients with acute MI and an ejection fraction >50% treated with a contemporary reperfusion strategy.

Nicola Ryan and Ali Nazmi Calik provide their take on the results which were presented...

Nicola Ryan

Author

Nicola Ryan

Author

Ali Nazmi Calik
REDUCE-AMI: Long-term beta-blocker treatment after AMI and preserved LVEF
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