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TAVI: nightmare in the cathlab - Part 3

18 Nov 2025 – From PCR London Valves 2025

This session reviews challenging complications encountered during TAVI procedures, highlighting emergent situations such as coronary occlusion and cardiac arrest. It also discusses unique cases including bicuspid aortic valve-related haemolysis, novel vascular access approaches like lithotripsy, and successful management of double perforation complications. The session provides critical...

TAVI complications - Part 5

18 Nov 2025 – From PCR London Valves 2025

This session highlights acute and urgent complications following TAVI implantation, including myocardial infarction, cardiac arrest, and challenging catheterization scenarios. It provides detailed case analyses illustrating the limits of TAVI procedures and the critical importance of prompt recognition and intervention in adverse events, enhancing clinician preparedness for...

Featured research - TAVI - Part 14

18 Nov 2025 – From PCR London Valves 2025

This featured research session presents pivotal findings on transcatheter aortic valve implantation (TAVI), including 30-day and one-year outcomes from the VANTAGE trial, novel concepts for assessing aortic stenosis severity, and the influence of mitral annular calcification on conduction disturbances. Additional topics cover the role of clinical...

Complex combined transcatheter interventions

18 Nov 2025 – From PCR London Valves 2025

This session addresses complex combined transcatheter interventions for multivalvular heart disease. It covers integrated transcatheter strategies for multiple valve pathologies, solutions for combined severe aortic stenosis and mitral regurgitation with heavy calcification, and approaches to concomitant atrial functional mitral and tricuspid regurgitation. The session also discusses...

TAVI: complex vascular access - Part 3

18 Nov 2025 – From PCR London Valves 2025

This session focuses on managing complex vascular access challenges in TAVI procedures. It includes case discussions on non-crossable aortic valve stenosis, transseptal TAVI for severe aortic regurgitation with porcelain aorta, and percutaneous implantation in patients with unconventional anatomy or conditions like shaggy syndrome. Strategies for severe...

TAVI valve-in-valve - Part 6

18 Nov 2025 – From PCR London Valves 2025

This session explores valve-in-valve TAVI procedures, addressing intricate cases such as triple valve scenarios, planning challenges in TAVI-in-TAVI, and overcoming obstacles in mitral valve-in-valve therapies. It also presents difficult cases involving dysfunctional stentless aortic bioprostheses and acute leaflet rupture during valve replacement, offering practical insights for...

TAVI: alternative access - Part 2

18 Nov 2025 – From PCR London Valves 2025

This session addresses alternative access routes for TAVI in patients with challenging vascular anatomy. Topics include transapical valve-in-valve procedures complicated by severe aortic regurgitation, percutaneous TAVI via the brachiocephalic trunk, and strategies for managing hostile vascular anatomies. Solutions for scenarios where transfemoral TAVI is not feasible...

Challenging mitral interventions

18 Nov 2025 – From PCR London Valves 2025

This session explores the complexities of mitral interventions, highlighting advancements and challenges in transcatheter mitral valve repair (TMVR). Topics include the benefits of a simplified single-step TMVR approach, the influence of hemodynamic parameters on MitraClip therapy outcomes, strategies for managing persistent pulmonary oedema, and approaches to...

TAVI and coronary artery disease - Part 2

18 Nov 2025 – From PCR London Valves 2025

This session focuses on the intersection of transcatheter aortic valve implantation (TAVI) and coronary artery disease, addressing complex clinical scenarios. It covers innovative approaches such as double "chimney" stenting with balloon-expandable TAVI, strategies for high-risk TAVR combined with multivessel PCI, advances in Medtronic Fx+ TAVR technology,...

When the interventional cardiologist meets the surgeon

18 Nov 2025 – From PCR London Valves 2025

This session highlights collaborative approaches between interventional cardiologists and surgeons in complex valve interventions. It includes cases such as transfemoral valve-in-valve TAVI in bio-Bentall patients with chronic aortic dissection, critical decision-making in life-threatening scenarios, the importance of access choice in TMVR, mechanical leaflet modification of failed...

TAV in TAVI with coronary protection - LIVE Case

18 Nov 2025 – From PCR London Valves 2025

Watch a LIVE case followed by a recorded case, regarding a 78-year-old female, with a previous TAVI in 2014 (Sapien 3 26) and sarcoidosis, who presented with symptomatic TAVI stenosis. There was a mis-commissural alignment, with the neoskirt plane above the coronary plane. Under general anesthesia,...

TAV in TAVI with coronary protection -  LIVE Case

Paravalvular leak closure - Part 4

18 Nov 2025 – From PCR London Valves 2025

This session delves into the complexities of paravalvular leak closure with a focus on challenging scenarios including unusual TAVI complications in the mitral position, management of mega paravalvular leaks using jumbo devices, and strategies when closure itself poses an obstacle. It also covers acute peri-operative aortic...

Imaging to the rescue

11 Dec 2025 – From GulfPCR-GIM 2025

This session highlighted the pivotal role of advanced intracoronary imaging techniques, particularly OCT, in complex case management such as in-stent restenosis and thrombus evaluation. Through real-world cases, it demonstrated how imaging complements physiology to guide therapeutic decisions, including the use of drug-coated balloons beyond native coronary...

Imaging to the rescue

Coronary Pot Pourri - 2

11 Dec 2025 – From GulfPCR-GIM 2025

This session presents a diverse range of complex coronary interventions, highlighting advanced techniques and strategies. Topics include the use of ECMO support for high-risk PCI and TAVI in cardiogenic shock, innovative approaches in left main interventions, challenging stent optimisation, and management of patients with combined severe...

Coronary Pot Pourri - 2

Innovations in stentless coronary intervention: from DCB technologies to bioresorbable scaffolds

11 Dec 2025 – From GulfPCR-GIM 2025

This session delves into the evolving landscape of stentless coronary interventions, focusing on the structural diversity of Drug-Coated Balloons (DCB) and the promising future of bioresorbable scaffolds (BRS). It emphasizes the role of intracoronary imaging, particularly OCT, in optimizing these therapies. Attendees gain a comprehensive understanding...

Innovations in stentless coronary intervention: from DCB technologies to bioresorbable scaffolds

Precision without a scaffold - When, why and how to use DCB in de novo lesions

11 Dec 2025 – From GulfPCR-GIM 2025

This session provided an in-depth examination of drug-coated balloon (DCB) use in de novo coronary lesions, emphasizing patient selection, lesion preparation, and procedural technique. Clinical evidence and real-world cases illustrated when and why DCBs represent a precise alternative to stenting, particularly in small vessels, high bleeding...

Precision without a scaffold - When, why and how to use DCB in de novo lesions

Angiography-derived fractional flow reserve versus intravascular ultrasound to guide percutaneous coronary intervention in patients with coronary artery disease: the FLAVOUR II trial

29 Mar 2025

Ali Nazmi Calik provides his take on the FLAVOUR II trial presented by Jian-An Wang at ACC.25 in Chicago.

Author

Ali Nazmi Calik
Angiography-derived fractional flow reserve versus intravascular ultrasound to guide percutaneous coronary intervention in patients with coronary artery disease: the FLAVOUR II trial

The AQUATIC trial: Assessment of quitting versus using aspirin therapy in patients with stabilized coronary artery disease after stenting who require long-term oral anticoagulation

01 Sep 2025

Chiara De Biase provides her take on the results of AQUATIC presented by Martine Gilard at ESC Congress 2025 in Madrid.

Author

Chiara De Biase
The AQUATIC trial [Assessment of quitting versus using aspirin therapy in patients with stabilized coronary artery disease after stenting who require long-term oral anticoagulation: Rationale for and design of the AQUATIC double-blind randomized trial]
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