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TAVI: unusual complications - Part 2

17 Nov 2025 – From PCR London Valves 2025

This session reviews unusual and severe complications encountered during TAVI procedures, such as aorto-right ventricular fistula, ventricular perforation, and sinus of Valsalva rupture. It highlights percutaneous treatment successes and endovascular interventions, offering critical insights into managing life-threatening procedural complications effectively.

TAVI embolisation - Part 1

18 Nov 2025 – From PCR London Valves 2025

This session explores the critical issue of TAVI valve embolisation, presenting real-world cases that emphasize rapid problem-solving and interventional management strategies. Discussions include bailout techniques for embolised valves, managing multiple valve implantations in severe aortic stenosis, and expectations for TAVI in pure aortic regurgitation. The session...

Multiple valve interventions

17 Nov 2025 – From PCR London Valves 2025

This session delves into the complexities of multiple valve interventions, showcasing a fully transcatheter strategy for combined complex heart procedures. It presents stepwise approaches for managing multivalvular disease with severe pulmonary hypertension and sequential transcatheter strategies when single valve treatment is insufficient. Additional focus is given...

TAVI embolisation - Part 2

18 Nov 2025 – From PCR London Valves 2025

This session focuses on managing complications related to TAVI valve embolisation and migration. It includes detailed case discussions on balloon-expandable valve dislocation into the left ventricle, intra-annular migration managed by valve-in-valve techniques, and successful strategies for self-expanding valve migration. The session underscores the importance of readiness...

Mitral TEER in complex scenarios

18 Nov 2025 – From PCR London Valves 2025

This session presents complex clinical scenarios in mitral transcatheter edge-to-edge repair (TEER), illustrating advanced procedural techniques and multidisciplinary management. Topics include on-circuit aspiration thrombectomy to facilitate TEER, combined interventions addressing multiple valve pathologies, timing considerations in healed mitral endocarditis, and TEER application in end-stage idiopathic cardiomyopathy....

Curious TAVI scenarios: solving complex anatomical and technical pitfalls

17 Nov 2025 – From PCR London Valves 2025

This session examines challenging and unusual scenarios encountered during transcatheter aortic valve implantation (TAVI). Topics include managing desaturation after transfemoral J-Valve implantation for pure NAVR, addressing procedural difficulties such as paddle release with Evolut TAVI, and utilizing snaring-assisted TAVI under cerebral embolic protection. It further explores...

Curious TAVI scenarios: solving complex anatomical and technical pitfalls

TAVI and coronary artery disease - Part 2

18 Nov 2025 – From PCR London Valves 2025

This session focuses on the intersection of transcatheter aortic valve implantation (TAVI) and coronary artery disease, addressing complex clinical scenarios. It covers innovative approaches such as double "chimney" stenting with balloon-expandable TAVI, strategies for high-risk TAVR combined with multivessel PCI, advances in Medtronic Fx+ TAVR technology,...

Featured research: imaging innovation and device performance in TAVI

18 Nov 2025 – From PCR London Valves 2025

This session presents featured research on TAVI, highlighting long-term outcomes and innovations in transcatheter aortic valve therapy. It includes registry data on mild paravalvular leak impact, five-year evaluations of the Hydra THV, comparisons between deep learning and manual echocardiographic assessments, pacemaker implantation outcomes post-TAVI, and procedural...

Featured research: imaging innovation and device performance in TAVI

BRIGHT-4 – Bivalirudin plus a high-dose infusion versus heparin monotherapy in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: a randomised trial

07 Nov 2022

Nicola Ryan provides her take on the BRIGHT-4 study, which was presented during AHA 2022 in Chicago, & simultaneously published in the Lancet.

This study was a randomised control trial designed to assess if bivalirudin plus a high dose infusion for 2-4 hours post PPCI was superior to unfractionated...

Nicola Ryan

Author

Nicola Ryan
BRIGHT-4 – Bivalirudin plus a high-dose infusion versus heparin monotherapy in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: a randomised trial

TRILUMINATE pivotal: A landmark randomized clinical trial of transcatheter tricuspid valve edge-to-edge repair for tricuspid regurgitation

04 Mar 2023

Jonathan Curio and Alex Sticchi provide their take on this clinical trial which was presented by Paul Sorajja at the American College of Cardiology Scientific Session (ACC.23/WCC).

Alessandro Sticchi

Author

Alessandro Sticchi
Jonathan Curio

Author

Jonathan Curio
Live from ACC.23/WCC: TRILUMINATE pivotal

Intravascular ultrasound-guided versus angiography-guided percutaneous coronary intervention in acute coronary syndromes: The multicenter, randomized, blinded, IVUS-ACS Trial

09 Apr 2024

Marco Spagnolo and Daniele Giacoppo report the main results of the IVUS-ACS trial presented by Shao-Liang Chen, from the Nanjing First Hospital, Nanjing Medical University, Nanjing, in a Featured Clinical Research session at ACC.24 in Atlanta and simultaneously published in The Lancet.(1)

Daniele Giacoppo

Author

Daniele Giacoppo
Marco Spagnolo

Author

Marco Spagnolo
IVUS-guided vs angiography-guided PCI in acute coronary syndromes
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