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Transcatheter mitral valve replacement - LIVE case

20 May 2026 – From EuroPCR 2026

A 65‑year‑old woman with obesity (BMI 38.7), prior cardiac surgery (CABG to OM and LAD in 2012), and chronic kidney disease presented with symptomatic severe mitral regurgitation (Carpentier type III: type IIIa due to calcification and type IIIb post‑MI) with moderately reduced LVEF (45%).

A transcatheter mitral...

Transcatheter mitral valve replacement - LIVE case

TAVI and coronary artery disease - LIVE case

19 May 2026 – From EuroPCR 2026

An 88-year-old woman with hypertension, dyslipidemia, paroxysmal AF, and moderate renal impairment presented with symptomatic severe aortic stenosis, with a small (396 mm²), horizontal annulus and preserved LV function. She also had CAD with severe OM and diagonal stenoses. CT showed a risk of left main...

TAVI and coronary artery disease - LIVE case

PCI of calcified distal left main stenosis - LIVE case

19 May 2026 – From EuroPCR 2026

A 54 year-old male with hypertention, smoker, dyslipidemia and history of OM and Diagnal PCI (2004) presented a significant LM-LAD calcified stenosis.

They prepared the proximal LAD lesion by IVL before implanted a 3.5-28 mm stent. Then, they prepared the LM lesion with NC predilatation, a cutting...

PCI of calcified distal left main stenosis - LIVE case

FFR- and IVUS-guided PCI of a long and calcified LAD lesion - LIVE case

19 May 2026 – From EuroPCR 2026

A 71‑year‑old man with hypertension and dyslipidemia presented with CCS class II angina and three‑vessel coronary artery disease. Functional assessment included CT‑derived micro‑FFR, angiography‑based FFR, and stress myocardial scintigraphy. The only hemodynamically significant lesion was a long, calcified lesion of the LAD.

Lesion preparation was performed with...

FFR- and IVUS-guided PCI of a long and calcified LAD lesion - LIVE case

TAVI in aortic regurgitation with a dedicated valve - LIVE case

20 May 2026 – From EuroPCR 2026

An 80-year-old male with chronic kidney disease, a history of colon cancer (2013), paroxysmal AF, and LAD PCI 2 weeks earlier presented with symptomatic severe type III AR. He had normal LV function, but early LV dilation. The mechanism of AR was a combination of primary...

TAVI in aortic regurgitation with a dedicated valve - LIVE case

Combined mitral repair and LAA closure with two separate septal punctures - LIVE case

21 May 2026 – From EuroPCR 2026

A 79‑year‑old man with hypertension, a history of basal cell carcinoma and psoriasis, presented with symptomatic severe primary MR (flail P2 due to ruptured chordae) and bleeding complications (recurrent skin bleeding) while on DOAC therapy for permanent atrial fibrillation.

Two G5 MitraClip devices were implanted. Subsequently, through...

Combined mitral repair and LAA closure with two separate septal punctures - LIVE case

Calcified lesion of distal protected left main - LIVE case

22 May 2026 – From EuroPCR 2026

An 85‑year‑old man with type 2 diabetes mellitus, hypertension, dyslipidemia, peripheral artery disease, COPD, and chronic kidney disease presented with CCS class II angina related to three‑vessel coronary artery disease. He had previously undergone hybrid revascularization, including PCI of the RCA ostium and CABG with LIMA...

Calcified lesion of distal protected left main - LIVE case

TAV-in-SAV TAVI procedure - LIVE case

21 May 2026 – From EuroPCR 2026

A 70‑year‑old man with COPD and a history of severe aortic stenosis treated with SAVR (27 mm Perimount Magna) in 2012, followed by endocarditis in 2013, presented with symptomatic degeneration of the surgical valve, predominantly as severe aortic regurgitation. Left ventricular function was preserved (LVEF 50%)...

TAV-in-SAV TAVI procedure - LIVE case

TAVI in extensive valve calcifications - LIVE case

22 May 2026 – From EuroPCR 2026

An 88‑year‑old woman with a history of dual‑chamber PPM and prior radiotherapy for breast cancer presented with symptomatic aortic stenosis and preserved left ventricular function.

A 27 mm Navitor Vision valve was implanted under local anesthesia using dual arterial access (femoral and right radial arteries).

LIVE Educational Case...

TAVI in extensive valve calcifications - LIVE case

Randomised comparison of intravascular lithotripsy vs. cutting balloon treatment in calcified coronary artery disease – The Short-CUT trial

27 Oct 2025

Aaysha Cader provides her take on the Short-CUT trial presented by Suzanne J. Baron at TCT 2025, in San Francisco.

Author

Aaysha Cader
Randomised comparison of intravascular lithotripsy vs. cutting balloon treatment in calcified coronary artery disease – The Short-CUT trial

Transcatheter aortic valve replacement in small aortic annuli: Results from the FRANCE-TAVI registry

17 Sep 2022

Mirvat Alasnag provides her take on the outcomes of small annuli sub-study from the FRANCE-TAVI Registry which included 1,195 patients. This trial was presented by Walid Ben-Ali at TCT 2022.

Dr. Mirvat Alasnag

Author

Mirvat Alasnag
Transcatheter aortic valve replacement in small aortic annuli: Results from the FRANCE-TAVI registry

RIPCORD 2: does routine pressure wire assessment influence management strategy of coronary angiography for diagnosis of chest pain?

29 Aug 2021

Nicola Ryan presents a synthesis of this study which compares FFR-guided assessment of patients with chest pain with angiographic guidance alone, and which was presented by Nicholas Curzen (Southampton, USA) during the ESC Congress 2021.

Nicola Ryan

Author

Nicola Ryan
RIPCORD 2: does routine pressure wire assessment influence management strategy of coronary angiography for diagnosis of chest pain?

Outcomes in patients with atrial fibrillation randomized to receive LAA closure or oral anticoagulation: Primary results of the CHAMPION-AF clinical trial

28 Mar 2026

During the first Late-Breaking Trial session of the 2026 ACC Congress held in New Orleans, Saibal Kar, principal investigator of the CHAMPION-AF trial, presented the 3-year results of this groundbreaking study, which were simultaneously published in the NEJM (DOI: 10.1056/NEJMoa2517213).

Luigi Biasco

Author

Luigi Biasco
CHAMPION-AF: LAAC vs oral anticoagulation in atrial fibrillation

Aortic stenosis and coronary artery disease: which should be treated first?

18 Jun 2026

In this review, Henryk Dreger explores the complex interplay between aortic stenosis and coronary artery disease, highlighting the latest evidence on PCI timing and its implications for clinical decision-making.

Henryk Dreger

Author

Henryk Dreger
Aortic stenosis and coronary artery disease: which should be treated first?

TRI.fr trial - Multicentric randomised evaluation of the transcatheter edge-to-edge repair in the treatment of severe isolated secondary tricuspid regurgitation

31 Aug 2024

Alex Sticchi provides his take on the results of the TRI.FR trial presented by Erwan Donal at the ESC Congress 2024 in London.

Alessandro Sticchi

Author

Alessandro Sticchi
Tri.fr trial

ILUMIEN IV: OPTIMAL PCI - Optical Coherence Tomography Guided Coronary Stent Implantation Compared with Angiography: A Multicenter Randomized Trial in Percutaneous Coronary Intervention

29 Aug 2023

Claudio Laudani and Daniele Giacoppo report the main results of the ILUMIEN IV trial presented by Ziad Ali, from the St. Francis Hospital, Roslyn, and Clinical Trials Center, Cardiovascular Research Foundation, New York, in a Hot Line session at the European Society of Cardiology congress 2023...

Claudio Laudani

Author

Claudio Laudani
Daniele Giacoppo

Author

Daniele Giacoppo
ILUMIEN IV: OCT versus angiography
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