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Early Career Research Award Final

17 Nov 2025 – From PCR London Valves 2025

Highlighting pioneering research in structural heart interventions, this session presents studies on the impact of transcatheter tricuspid valve replacement (TTVR) on left ventricular geometry and function, myocardial remodeling in aortic stenosis, physiological responses after mitral and tricuspid edge-to-edge repairs, advancing the understanding of device effects on...

Tricuspid interventions: knowns and unknowns

17 Nov 2025 – From PCR London Valves 2025

Explore the evolving landscape of transcatheter tricuspid valve interventions in this session, which presents the latest evidence from registries and randomized trials. Discussions include the new Euro tricuspid regurgitation risk score, clinical controversies, real-world patient scenarios, and insights into optimal medical therapy and device selection to...

Tricuspid interventions: knowns and unknowns

Learning from lived experience and contemporary evidence: shaping the treatment of women with heart valve disease

17 Nov 2025 – From PCR London Valves 2025

This session provides an in-depth exploration of the lived experiences of women with valvular heart disease, emphasizing the unique challenges in detection, diagnosis, treatment, and follow-up. It integrates contemporary evidence and the forthcoming 2025 ESC/EACTS guidelines to offer practice-ready strategies tailored to the management of valvular...

Transcatheter mitral valve-in-valve, valve-in-ring, and valve-in-MAC

17 Nov 2025 – From PCR London Valves 2025

This session provides an expert overview of transcatheter mitral valve-in-valve, valve-in-ring, and valve-in-MAC procedures. It focuses on unique anatomical and technical considerations, advanced imaging and pre-procedural planning methods, and procedural techniques including device selection and sizing, guided by experienced high-volume operators to optimize procedural success.

Transcatheter mitral valve-in-valve, valve-in-ring, and valve-in-MAC

Featured research - Mitral valve interventions: Physiology & device innovation

17 Nov 2025 – From PCR London Valves 2025

This session highlights groundbreaking research on mitral valve interventions featuring advanced transcatheter techniques. Topics include coronary physiology assessment with vFFR in severe mitral regurgitation, predictive versus actual outcomes in TMVR, innovative devices like Epygon and INNOVALVE, and novel approaches such as the ReNiva posterior leaflet replacement...

Featured research - Mitral valve interventions: Physiology & device innovation

Featured research - Tricuspid valve intervention: the TRIPLACE registry

17 Nov 2025 – From PCR London Valves 2025

This session features cutting-edge research on tricuspid valve interventions, including insights from the TRIPLACE registry on orthotopic TTVR thrombosis, predictive value of three-dimensional tricuspid annulus measurements for procedural outcomes, early clinical experiences with novel TTVR systems, and procedural clipping strategies based on results from the BRIGHT...

Featured research - Tricuspid valve intervention: the TRIPLACE registry

Left atrial appendage occlusion

17 Nov 2025 – From PCR London Valves 2025

This session focuses on the complexities and innovations in left atrial appendage occlusion (LAAO) procedures. It covers transesophageal ICE monitoring, challenges posed by existing atrial septal occluders, combined surgical and percutaneous approaches, and the practical experience with the Ultraseal device. These insights advance understanding of procedural...

Featured research - TAVI: Predictive tools, AI innovation and reintervention strategies

17 Nov 2025 – From PCR London Valves 2025

This session presents cutting-edge research in TAVI, covering the development of predictive models for clinical valve thrombosis, comparative analyses between self-expandable and balloon-expandable valves from the Greek TAVI registry, and the emerging role of AI-guided Heart Team decisions. It also examines outcomes of reintervention strategies following...

Featured research - TAVI: Predictive tools, AI innovation and reintervention strategies

TAVI: complex vascular access

17 Nov 2025 – From PCR London Valves 2025

This session addresses the challenges of complex vascular access in transcatheter aortic valve implantation (TAVI). It discusses strategies for navigating difficult thoraco-abdominal aortic anatomies, managing double aortic arches, and overcoming hostile femoral access. Case studies illustrate meticulous planning and innovative solutions essential for successful TAVI in...

TAVI valve-in-valve - Challenging clinical scenarios

17 Nov 2025 – From PCR London Valves 2025

This session focuses on the complexities of valve-in-valve TAVI procedures, highlighting challenging clinical scenarios such as managing severely regurgitant rapid deployment valves and degenerated stentless bioprostheses. It provides detailed insights into overcoming procedural barriers and strategies for complex valve-in-valve transcatheter aortic valve replacement (TAVR) interventions.

TAVI valve-in-valve - Challenging clinical scenarios

TAVI: nightmare in the cathlab - Annular perforation, coronary obstruction & balloon rupture

17 Nov 2025 – From PCR London Valves 2025

This session presents critical case analyses of complicated TAVI procedures, highlighting unexpected and severe intra-procedural events such as annular perforation, leaflet modification complications, coronary obstructions, and device failures. It emphasizes prevention strategies, bailout techniques, and acute management to prepare clinicians for handling TAVI-related emergencies effectively.

TAVI: nightmare in the cathlab - Annular perforation, coronary obstruction & balloon rupture

TAVI: alternative access

17 Nov 2025 – From PCR London Valves 2025

This session addresses alternative access routes for TAVI in patients with challenging vascular anatomies. It includes innovative approaches such as transapical TAV-in-TAV procedures, transcaval implantation in emergency settings, and techniques for patients with hostile iliofemoral access, showcasing adaptive strategies when conventional access is not feasible.

TAVI in challenging annular anatomy

17 Nov 2025 – From PCR London Valves 2025

This session addresses the complexities of performing TAVI in challenging annular anatomies. It features case studies such as TAVI-in-TAVI in a patient with Morquio syndrome, strategies for managing severe annular calcification including calcium cracking techniques, and the use of large-diameter Myval valves for very large annuli...

TAVI in challenging scenarios

17 Nov 2025 – From PCR London Valves 2025

This session explores complex and emergent scenarios in TAVI, featuring cases such as emergent transfemoral TAVI in failing homograft roots complicated by extensive aortic dissection, the use of BASILICA in high-risk left main occlusion terrain, and the aorto-mitral challenges during TAVR. It also covers innovative coronary...

Mitral TEER and LAA closure - LIVE Case

17 Nov 2025 – From PCR London Valves 2025

Watch a LIVE case followed by a recorded case regarding a 91-year-old female with permanent AF, LAD PCI three months earlier, and recurrent GID bleeding who presented with symptomatic severe primary mitral regurgitation due to P2 prolapse and flail. CT imaging showed a LAA with a...

Mitral TEER and LAA closure -  LIVE Case

Transcatheter mitral valve-in-valve: alternative strategy for optimal alignment

17 Nov 2025 – From PCR London Valves 2025

This session focuses on transcatheter mitral valve-in-valve procedures, emphasizing alternative strategies for optimal alignment and lifetime management planning. It delves into engineering the landing zone for challenging anatomies, the integration of the LAMPOON procedure in TMVR valve-in-valve cases, and addresses complexities arising from mitral annular calcification.

Transcatheter mitral valve-in-valve: alternative strategy for optimal alignment

TAVI Valve-in-Valve: Managing unexpected anatomical challenges

17 Nov 2025 – From PCR London Valves 2025

This session examines valve-in-valve interventions in TAVI, highlighting management of concomitant left main disease, unique case narratives such as "The Highlander story," and the unpredictability inherent in these procedures. It also reviews successful transfemoral TAV-in-SAV interventions in acute heparin-induced thrombocytopenia and addresses treatment of degenerated sutureless...

TAVI Valve-in-Valve: Managing unexpected anatomical challenges

TAVI in patients with concomitant valve and coronary artery disease

17 Nov 2025 – From PCR London Valves 2025

Focused on patients with concomitant valve and coronary artery disease, this session examines evaluation strategies for aortic stenosis burden, integrates recent trial data on combined TAVI and PCI, and discusses optimal management approaches in complex multi-valve disease scenarios through detailed case presentations and clinical outcomes.

TAVI in patients with concomitant valve and coronary artery disease

Paravalvular leak closure - Part 2

17 Nov 2025 – From PCR London Valves 2025

This session is dedicated to paravalvular leak (PVL) closure techniques, featuring percutaneous approaches after surgical valve implantation and TAVI complications such as annulus rupture. It includes advanced management using multiple plugs for long-tunnel mitral PVLs, innovative transformation from pop-up to plug strategies, and transapical approaches following...

Unravel the complexity of multi-valve disease

17 Nov 2025 – From PCR London Valves 2025

This session unpacks the complexities inherent in multi-valve disease involving combined mitral and tricuspid regurgitation. It emphasizes diagnostic challenges, the critical role of invasive hemodynamics in decision-making, and strategies for optimal timing and staging of interventions, demonstrated through illustrative patient cases.

Unravel the complexity of multi-valve disease
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