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Featured research - Mitral valve interventions - Part 4

18 Nov 2025 – From PCR London Valves 2025

This research-focused session presents contemporary evidence and clinical outcomes related to mitral valve interventions. It includes data on transapical mitral valve-in-ring implantation from the European Tendyne registry, prognostic utility of CT-derived fatty muscle fraction in mitral TEER, and comparative outcomes between transapical TMVR and mitral TEER....

Best clinical cases & Early Career Research Award

17 Nov 2025 – From PCR London Valves 2025

Explore a series of innovative clinical cases highlighting the integration of advanced expertise and AI in managing complex structural heart interventions. This session includes compelling cases such as the use of ANCHOR BASILICA to prevent coronary obstruction, the Lithotripsy-BATMAN technique for mitral valve interventions in calcified...

Best clinical cases & Early Career Research Award

Paravalvular leak closure - Part 3

18 Nov 2025 – From PCR London Valves 2025

This session addresses the complexities of paravalvular leak closure, emphasizing resilience in procedural approaches. It covers sizing balloon techniques that enhance treatment efficacy in aortic paravalvular leaks and explores closure strategies following Ozaki procedures. Management of mitral paravalvular leaks in high-risk patients and innovative solutions for...

TAVI embolisation - Part 1

18 Nov 2025 – From PCR London Valves 2025

This session explores the critical issue of TAVI valve embolisation, presenting real-world cases that emphasize rapid problem-solving and interventional management strategies. Discussions include bailout techniques for embolised valves, managing multiple valve implantations in severe aortic stenosis, and expectations for TAVI in pure aortic regurgitation. The session...

Transcatheter tricuspid valve replacement - LIVE Case

18 Nov 2025 – From PCR London Valves 2025

Live case: An 86-year-old male, with a history of PPM, permanent AF, CKD stage 3, and moderately impaired LV function (50–55%), presented with symptomatic torrential mixed TR (tricuspid annular dilatation and pacing lead on the septal leaflet). An Evoque valve was implanted under fluoroscopy and TEE...

Transcatheter tricuspid valve replacement - LIVE Case

Transcatheter tricuspid valve replacement: pioneering techniques and solutions for high-risk patients

18 Nov 2025 – From PCR London Valves 2025

This session explores advanced transcatheter tricuspid valve replacement techniques and outcomes. It features cases of TricValve dysfunction due to intrinsic regurgitation, pioneering 'chimney technique' implantation in complex patients, right heart remodeling post-intervention, and innovative solutions including percutaneous heterotopic bicaval valve implantation following pericardiectomy.

Transcatheter tricuspid valve replacement: pioneering techniques and solutions for high-risk patients

Featured research - TAVI - Part 14

18 Nov 2025 – From PCR London Valves 2025

This featured research session presents pivotal findings on transcatheter aortic valve implantation (TAVI), including 30-day and one-year outcomes from the VANTAGE trial, novel concepts for assessing aortic stenosis severity, and the influence of mitral annular calcification on conduction disturbances. Additional topics cover the role of clinical...

Complex combined transcatheter interventions

18 Nov 2025 – From PCR London Valves 2025

This session addresses complex combined transcatheter interventions for multivalvular heart disease. It covers integrated transcatheter strategies for multiple valve pathologies, solutions for combined severe aortic stenosis and mitral regurgitation with heavy calcification, and approaches to concomitant atrial functional mitral and tricuspid regurgitation. The session also discusses...

TAVI: complex vascular access - Part 3

18 Nov 2025 – From PCR London Valves 2025

This session focuses on managing complex vascular access challenges in TAVI procedures. It includes case discussions on non-crossable aortic valve stenosis, transseptal TAVI for severe aortic regurgitation with porcelain aorta, and percutaneous implantation in patients with unconventional anatomy or conditions like shaggy syndrome. Strategies for severe...

TAVI valve-in-valve - Part 6

18 Nov 2025 – From PCR London Valves 2025

This session explores valve-in-valve TAVI procedures, addressing intricate cases such as triple valve scenarios, planning challenges in TAVI-in-TAVI, and overcoming obstacles in mitral valve-in-valve therapies. It also presents difficult cases involving dysfunctional stentless aortic bioprostheses and acute leaflet rupture during valve replacement, offering practical insights for...

TAVI: alternative access - Part 2

18 Nov 2025 – From PCR London Valves 2025

This session addresses alternative access routes for TAVI in patients with challenging vascular anatomy. Topics include transapical valve-in-valve procedures complicated by severe aortic regurgitation, percutaneous TAVI via the brachiocephalic trunk, and strategies for managing hostile vascular anatomies. Solutions for scenarios where transfemoral TAVI is not feasible...

Challenging mitral interventions

18 Nov 2025 – From PCR London Valves 2025

This session explores the complexities of mitral interventions, highlighting advancements and challenges in transcatheter mitral valve repair (TMVR). Topics include the benefits of a simplified single-step TMVR approach, the influence of hemodynamic parameters on MitraClip therapy outcomes, strategies for managing persistent pulmonary oedema, and approaches to...

TAVI and coronary artery disease - Part 2

18 Nov 2025 – From PCR London Valves 2025

This session focuses on the intersection of transcatheter aortic valve implantation (TAVI) and coronary artery disease, addressing complex clinical scenarios. It covers innovative approaches such as double "chimney" stenting with balloon-expandable TAVI, strategies for high-risk TAVR combined with multivessel PCI, advances in Medtronic Fx+ TAVR technology,...

When the interventional cardiologist meets the surgeon

18 Nov 2025 – From PCR London Valves 2025

This session highlights collaborative approaches between interventional cardiologists and surgeons in complex valve interventions. It includes cases such as transfemoral valve-in-valve TAVI in bio-Bentall patients with chronic aortic dissection, critical decision-making in life-threatening scenarios, the importance of access choice in TMVR, mechanical leaflet modification of failed...

TAV in TAVI with coronary protection - LIVE Case

18 Nov 2025 – From PCR London Valves 2025

Watch a LIVE case followed by a recorded case, regarding a 78-year-old female, with a previous TAVI in 2014 (Sapien 3 26) and sarcoidosis, who presented with symptomatic TAVI stenosis. There was a mis-commissural alignment, with the neoskirt plane above the coronary plane. Under general anesthesia,...

TAV in TAVI with coronary protection -  LIVE Case

Paravalvular leak closure - Part 4

18 Nov 2025 – From PCR London Valves 2025

This session delves into the complexities of paravalvular leak closure with a focus on challenging scenarios including unusual TAVI complications in the mitral position, management of mega paravalvular leaks using jumbo devices, and strategies when closure itself poses an obstacle. It also covers acute peri-operative aortic...

Five-year outcomes of the randomised trial of fractional flow reserve guided PCI compared to coronary artery bypass grafting: FAME 3

02 Apr 2025

Kalaivani Mahadevan provides her take on the five-year outcomes of the FAME 3 trial presented by William F. Fearon at ACC.25 in Chicago.

Kalaivani Mahadevan

Author

Kalaivani Mahadevan
FFR-guided PCI vs CABG: 5-year results of the FAME 3 trial

ECMO-CS – Extracorporeal membrane oxygenation in the therapy of cardiogenic shock: primary results from the multicenter, randomized ECMO-CS trial

07 Nov 2022

Mirvat Alasnag provides her take on the ECMO-CS trial, which was presented during AHA 2022 in Chicago, and simultaneously published in Circulation. 

Dr. Mirvat Alasnag

Author

Mirvat Alasnag
ECMO-CS – Extracorporeal membrane oxygenation in the therapy of cardiogenic shock: primary results from the multicenter, randomized ECMO-CS trial

Early intra-aortic balloon pump in heart failure complicated by cardiogenic shock: The Altshock-2 randomized clinical trial

31 Mar 2025

Mirvat Alasnag provides her take on the Altshock-2 randomized clinical trial which was presented by Alice Sacco at ACC.25 in Chicago.

Dr. Mirvat Alasnag

Author

Mirvat Alasnag
Early intra-aortic balloon pump in heart failure complicated by cardiogenic shock: The Altshock-2 randomized clinical trial

Routine cerebral embolic protection in transcatheter aortic valve implantation: the British Heart Foundation (BHF) PROTECT-TAVI trial

29 Mar 2025

Aaysha Cader and Ali Nazmi Calik provide their take on the BHF PROTECT-TAVI trial, presented by Rajesh Kharbanda at ACC.25 in Chicago.

Author

Aaysha Cader

Author

Ali Nazmi Calik
Routine cerebral embolic protection in TAVI: the British Heart Foundation (BHF) PROTECT-TAVI trial
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