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Complications of mitral TEER

18 Nov 2025 – From PCR London Valves 2025

This session addresses complications associated with mitral transcatheter edge-to-edge repair (TEER), showcasing innovative bailout methods such as snare-assisted retrieval of undeployed devices, managing leaflet perforations with latest-generation devices, cases of valve-adjacent tears, mechanical support considerations when pumps fail, and the clinical impact of iatrogenic fossa ovalis...

Complications of paravalvular leak closure

18 Nov 2025 – From PCR London Valves 2025

This session addresses the complexities and risks associated with paravalvular leak (PVL) closure. It offers detailed analysis of principal complications, prevention techniques, and practical management strategies shared by experienced operators. Case studies illustrate complications such as device embolisation, prosthetic valve disc impingement, and delivery failures, along...

TAVI complications - Part 2

17 Nov 2025 – From PCR London Valves 2025

This session explores complex and uncommon complications associated with TAVI procedures, highlighting challenging clinical scenarios such as neurological complications in bicuspid valves, management of critically unstable left ventricles, and outcomes in complex valve interventions. Each topic offers valuable lessons for improving procedural safety and patient outcomes...

Getting to the heart of access: mastering femoral puncture and vascular closure

18 Nov 2025 – From PCR London Valves 2025

This session provides an in-depth understanding of femoral anatomy and the critical role of imaging in ensuring safe vascular access via femoral puncture. It covers the latest equipment used for vascular access and closure, highlighting haemostasis techniques and closure devices. Interactive case scenarios offer practical insights...

Thrombotic complications of transcatheter valves

17 Nov 2025 – From PCR London Valves 2025

Focusing on thrombotic complications following transcatheter valve implantation, this session presents a series of complex cases illustrating acute and late thrombotic events, their clinical presentations, and the pivotal role of multimodality imaging in diagnosis and management. Insights include coronary embolism and cardiogenic shock scenarios, emphasizing challenges...

TAVI embolisation - Part 1

18 Nov 2025 – From PCR London Valves 2025

This session explores the critical issue of TAVI valve embolisation, presenting real-world cases that emphasize rapid problem-solving and interventional management strategies. Discussions include bailout techniques for embolised valves, managing multiple valve implantations in severe aortic stenosis, and expectations for TAVI in pure aortic regurgitation. The session...

Multiple valve interventions

17 Nov 2025 – From PCR London Valves 2025

This session delves into the complexities of multiple valve interventions, showcasing a fully transcatheter strategy for combined complex heart procedures. It presents stepwise approaches for managing multivalvular disease with severe pulmonary hypertension and sequential transcatheter strategies when single valve treatment is insufficient. Additional focus is given...

Transcatheter tricuspid valve replacement - LIVE Case

18 Nov 2025 – From PCR London Valves 2025

Live case: An 86-year-old male, with a history of PPM, permanent AF, CKD stage 3, and moderately impaired LV function (50–55%), presented with symptomatic torrential mixed TR (tricuspid annular dilatation and pacing lead on the septal leaflet). An Evoque valve was implanted under fluoroscopy and TEE...

Transcatheter tricuspid valve replacement - LIVE Case

Featured research: imaging innovation and device performance in TAVI

18 Nov 2025 – From PCR London Valves 2025

This session presents featured research on TAVI, highlighting long-term outcomes and innovations in transcatheter aortic valve therapy. It includes registry data on mild paravalvular leak impact, five-year evaluations of the Hydra THV, comparisons between deep learning and manual echocardiographic assessments, pacemaker implantation outcomes post-TAVI, and procedural...

Featured research: imaging innovation and device performance in TAVI

Complications of valve-in-valve TAVI

18 Nov 2025 – From PCR London Valves 2025

This session addresses the complex complications associated with valve-in-valve TAVI procedures. Topics include delayed coronary compromise, unexpected clinical scenarios, the importance of recognizing surgical bioprosthesis types, the dual role of calcium in TAVI, and intricate left ventricular complications that can arise post valve-in-valve interventions.

Challenging mitral interventions

18 Nov 2025 – From PCR London Valves 2025

This session explores the complexities of mitral interventions, highlighting advancements and challenges in transcatheter mitral valve repair (TMVR). Topics include the benefits of a simplified single-step TMVR approach, the influence of hemodynamic parameters on MitraClip therapy outcomes, strategies for managing persistent pulmonary oedema, and approaches to...

TAVI: alternative access - Part 2

18 Nov 2025 – From PCR London Valves 2025

This session addresses alternative access routes for TAVI in patients with challenging vascular anatomy. Topics include transapical valve-in-valve procedures complicated by severe aortic regurgitation, percutaneous TAVI via the brachiocephalic trunk, and strategies for managing hostile vascular anatomies. Solutions for scenarios where transfemoral TAVI is not feasible...

Artificially synthesized optical coherence tomography images based on intravascular ultrasound-virtual histology examination of diseased coronary artery

05 May 2021

Intravascular imaging is a cornerstone of invasive management of coronary disease, requiring specialized training to interpret either IVUS or OCT. AI can facilitate interpretation by non-specialists in real time.

AI-generated synthetic OCT

BRIGHT-4 – Bivalirudin plus a high-dose infusion versus heparin monotherapy in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: a randomised trial

07 Nov 2022

Nicola Ryan provides her take on the BRIGHT-4 study, which was presented during AHA 2022 in Chicago, & simultaneously published in the Lancet.

This study was a randomised control trial designed to assess if bivalirudin plus a high dose infusion for 2-4 hours post PPCI was superior to unfractionated...

Nicola Ryan

Author

Nicola Ryan
BRIGHT-4 – Bivalirudin plus a high-dose infusion versus heparin monotherapy in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: a randomised trial

ENVISAGE-TAVI AF: edoxaban vs. vitamin K antagonists after TAVI in patients with atrial fibrillation

31 Aug 2021

Following the Hot Line session of the ESC Congress 2021 presented by George Dangas (New-York, USA), Daniele Giacoppo offers us a condensed version of this study.

Daniele Giacoppo

Author

Daniele Giacoppo
ENVISAGE-TAVI AF: edoxaban vs. vitamin K antagonists after TAVI in patients with atrial fibrillation

Transcatheter aortic valve replacement in small aortic annuli: Results from the FRANCE-TAVI registry

17 Sep 2022

Mirvat Alasnag provides her take on the outcomes of small annuli sub-study from the FRANCE-TAVI Registry which included 1,195 patients. This trial was presented by Walid Ben-Ali at TCT 2022.

Dr. Mirvat Alasnag

Author

Mirvat Alasnag
Transcatheter aortic valve replacement in small aortic annuli: Results from the FRANCE-TAVI registry

Long-term beta-blocker treatment after acute myocardial infarction and preserved left ventricular ejection fraction: The REDUCE-AMI Trial

07 Apr 2024

REDUCE-AMI is a multicentre, registry-based, prospective open-label parallel-group randomised clinical trial evaluating the benefit of beta-blocker treatment in patients with acute MI and an ejection fraction >50% treated with a contemporary reperfusion strategy.

Nicola Ryan and Ali Nazmi Calik provide their take on the results which were presented...

Nicola Ryan

Author

Nicola Ryan

Author

Ali Nazmi Calik
REDUCE-AMI: Long-term beta-blocker treatment after AMI and preserved LVEF
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