Focusing on patients with high bleeding risk undergoing PCI, this session presents contemporary evidence on prevalence, procedural strategies with different stent types, antiplatelet therapy considerations including diabetic and sex-specific outcomes, and novel technologies such as sirolimus-coated balloons and machine learning models for restenosis prediction.

This session provides an in-depth review of registries and clinical trials focused on transcatheter mitral valve replacement (TMVR). It presents data on annular and ventricular remodeling with the HighLife system, mid- to long-term valve performance, and innovations in transseptal TMVR using novel bioprostheses.

This session focuses on non-occlusive causes of acute coronary syndromes (ACS) when angiograms do not reveal clear pathology. It emphasizes the diagnostic value of intracoronary imaging for conditions such as MINOCA and spontaneous coronary artery dissection (SCAD), and discusses optimal treatment strategies and prognostic considerations.

This session explores the use of stentless percutaneous coronary interventions (PCI) employing drug-coated balloons (DCB) and bioresorbable scaffolds (BVS) in complex coronary scenarios. Through detailed case discussions, it addresses decision-making processes, technical considerations, and practical tips for successfully completing PCI without permanent stenting.

Aortic stenosis (AS) is the most common valvular heart disease leading to intervention. It is characterized by progression from leaflet thickening and calcification to significant haemodynamic stenosis which results in disease-specific symptoms and physical limitations as well as poor prognosis and impaired quality of life if...

Ali Nazmi Calik reviews Amulet IDE, a prospective, randomized, multi-center and active-control trial designed to compare the Amulet and Watchman 2.5 devices in a head-to-head fashion, and presented by Dhanunjaya Lakkireddy during TCT 2021.

Alex Sticchi provides his take on the final results of the MAnagement of high bleeding risk patients post bioresorbable polymer coated STEnt implantion with an abbReviated versus prolonged DAPT regimen

Alex Sticchi provides his take on the PASCAL IID Registry and an initial comparison with the CLASP IID. The trial was presented by Jörg Hausleiter during TCT Congress 2022.

Luigi Biasco provides his take on the results of the EARLY TAVR trial, presented by Philippe Genereux at TCT 2024 in Washington.

Ali Nazmi Calik provides his take on OPTION, which was presented during AHA 2022 in Chicago.

Nicola Ryan provides her take on the results of TAILORED-CHIP presented by Duk-Woo Park at the ESC Congress 2025 in Madrid.

Luigi Biasco provides his take on a sub-analysis of the Early TAVR trial about the early and delayed aortic valve replacement implant patients presented by Philippe Genereux at ACC.25 in Chicago.