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What are the key considerations for transcatheter mitral paravalvular leak management?

18 Nov 2025 – From PCR London Valves 2025

Nina Wunderlich and Patrick Calvert discuss mitral paravalvular leaks, which are relatively common. Percutaneous closure is now the default approach, and imaging is central to success: detailed pre-procedural assessment, 3D TOE during the procedure, and careful planning of transseptal puncture. 

This interview was filmed at PCR London...

What are the key considerations for transcatheter mitral paravalvular leak management?

TAVI: high coronary risk - Part 2

16 Nov 2025 – From PCR London Valves 2025

This session presents advanced strategies to mitigate high coronary risk during valve-in-valve TAVR procedures, including the LLAMACORN technique and chimney stenting to prevent coronary obstruction. It discusses management of misaligned prostheses, complex aortic and coronary anatomies, and innovative approaches such as stent crush techniques to ensure...

What are the key steps in pre procedural assessment for successful LAA closure?

16 Nov 2025 – From PCR London Valves 2025

Lorenz Räber and Kasper Korsholm highlight why pre-procedural imaging—particularly cardiac CT—has become essential for successful left atrial appendage occlusion (LAAO). They explain that the LAA is highly variable between patients, making detailed planning crucial for safety, device selection, and optimal procedural results.

This interview was filmed at...

What are the key steps in pre procedural assessment for successful LAA closure?

How to manage patients with aortic stenosis and coronary artery disease?

04 Mar 2026 – From PCR London Valves 2025

Tiffany Patterson and Davide Capodanno address the increasingly common scenario of managing coronary artery disease (CAD) in patients undergoing TAVI. With up to half of TAVI candidates presenting with CAD, they highlight new evidence from NOTION-3 showing that revascularization reduces major adverse cardiac events. The takeaway:...

How to manage patients with aortic stenosis and coronary artery disease?

Complex mitral and tricuspid TEER

16 Nov 2025 – From PCR London Valves 2025

This session highlights complex cases in mitral and tricuspid transcatheter edge-to-edge repair (TEER), addressing challenges such as septal obstacles in patients with old atrial septal occluders, management of residual atrial septal defects post-mitral valve-in-ring replacement, and innovative multidisciplinary approaches. It also covers hybrid transapical mitral valve-in-valve...

When the first TAVI fails: no panic, just planning

19 Jan 2026

An 81-year-old man with history of severe aortic stenosis previously treated with a balloon-expandable transcatheter valve was referred for progressive exertional dyspnea due to bioprosthetic valve degeneration.

How would you treat this patient?

Barbara Bellini

Author

Barbara Bellini
When the first TAVI fails: no panic, just planning

Spotlight on a selection of top Late-breaking Trials presented at PCR London Valves 2025

17 Nov 2025

View a snapshot of the results of these 4 trials in valvular and structural interventions presented in London during this year's Heart Team Course!

Selection of top Late-breaking Trials presented at #PCRLV

Retrieval of embolised devices

16 Nov 2025 – From PCR London Valves 2025

This session delves into the complex scenarios of embolised device retrieval, exploring various interventions such as management of Lambre device embolisation, alternatives to surgery for superior vena cava baffle stent embolisation, novel strategies for chronically embolised Gore Helex atrial septal occluder device retrieval, and challenging redo...

Validation of intravascular ultrasound-defined optimal stent expansion criteria for favorable 1-year clinical outcomes

17 Nov 2025

This individual patient data analysis of the three largest RCTs evaluating IVUS-guided stent optimisation showed that an MSA > 5.5 mm2 was associated with reduced TVF at one year. 

Ruxandra Sava

Reviewer

Ruxandra Sava
Nicola Ryan

Reviewer

Nicola Ryan
Validation of IVUS-defined optimal stent expansion criteria for favorable 1-year clinical outcomes

PCR: Collaborative, inclusive and global

15 Nov 2025 – From PCR London Valves 2025

At PCR, collaboration and inclusion are at the heart of everything we do.

Together, we create an environment where expertise is shared, talents complement each other, and diversity becomes a strength. It is this collective spirit that drives interventional cardiology forward and inspires innovation every day.

During PCR London...

PCR: Collaborative, inclusive and global

Late-breaking evidence in structural and coronary interventions - Part 2

16 Nov 2025 – From PCR London Valves 2025

This session presents the latest data from pivotal late-breaking trials in interventional cardiology. Highlights include one-year results from the ADALA trial, first-in-man use of the Vivasure PerQseal Elite for large hole arterial closure, two-year outcomes of the DragonFly system in China, six-month European outcomes, and insights...

The Top Late-Breaking Trials - Part 2

Meril Life Sciences presents one-year outcomes from the LANDMARK randomized controlled trial at PCR London Valves 2025

16 Nov 2025

GulfPCR-GIM 2025: the Training Programme is now available!

Check out details of the GulfPCR Workshops taking place in the Training Village
Get an overview of what’s in store!

PCR London Valves 2025 Welcome Ceremony

16 Nov 2025 – From PCR London Valves 2025

The PCR London Valves 2025 Welcome Ceremony marks the commencement of the conference, setting the stage for an immersive exploration of the latest advances and innovations in valvular heart disease management with a focus on transcatheter interventions.

PCR London Valves 2025 Welcome Ceremony

Redo TAVI with pre and post dilatation - LIVE Case

16 Nov 2025 – From PCR London Valves 2025

Watch this live case followed by a live in a box case, regarding a 93-year-old woman with hypertension, chronic bronchitis, and a history of TAVI with a Sapien 3 23 mm (2016) who presented with symptomatic severe aortic stenosis and mildly reduced LV function (50%). An...

Redo TAVI with pre and post dilatation - LIVE Case

The Silk Road of MedTech

16 Nov 2025 – From PCR London Valves 2025

Discover pioneering MedTech innovations along the Silk Road, including novel sheath designs for minimalist TAVR, self-expanding valves for pure aortic regurgitation, automated CT quantification via deep learning, and first-in-man experiences with cutting-edge valvuloplasty and TEER devices.

Innovations in TAVR: clinical insights and future perspectives

16 Nov 2025 – From PCR London Valves 2025

Presenting featured research on TAVI, this session covers outcomes from centers without on-site cardiac surgery, comparative leaflet modification techniques, conscious sedation protocols, left ventricular health in timing TAVR, and long-term valve durability insights including seven-year follow-up data.

Innovations in TAVR: clinical insights and future perspectives

Cutting-edge research in transcatheter tricuspid valve therapies

16 Nov 2025 – From PCR London Valves 2025

This session highlights cutting-edge research on tricuspid valve interventions, including the impact of inflow gradients on outcomes, global registry data on bicaval valve therapy, patient selection algorithms, and prognostic score validations for severe tricuspid regurgitation.

Cutting-edge research in transcatheter tricuspid valve therapies

TAVI in bicuspid anatomy

16 Nov 2025 – From PCR London Valves 2025

Explore the complexities of performing TAVI in bicuspid aortic valve anatomies, with expert discussions on BASILICA tricuspidisation, procedural planning for extreme calcification, valve sizing, and challenges associated with type 0 bicuspid valves and severe calcification.

TAVI valve-in-valve

16 Nov 2025 – From PCR London Valves 2025

This session presents complex valve-in-valve TAVI cases, illustrating advanced techniques such as valve fracture and snaring in difficult anatomies, approaches for pure aortic regurgitation in degenerated surgical valves, and strategies overcoming challenges in stentless bioprostheses and previous aortic repairs.

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