This session explores the integration of artificial intelligence with advanced imaging modalities in coronary interventions. Topics include quantitative myocardial blood flow assessment via co-registered CCTA and angiography, AI-guided real-time procedural support, novel video frame interpolation techniques, high-risk plaque identification through AI-derived OCT stress mapping, and validation...

This session covers acute management of STEMI presenting with cardiogenic shock, illustrating advanced interventional strategies and support devices such as ECMO, IABP, and Impella. It reviews complex clinical scenarios including acute left main occlusion and multivessel disease, offering critical insights into emergent care and decision-making.

This session provides an in-depth evaluation of stent failure using intracoronary imaging modalities such as IVUS and OCT. It presents diverse cases illustrating late drug-eluting stent failure, in-stent restenosis, neoatherosclerosis, and complications following rotational atherectomy, underscoring imaging's role in diagnosis and guiding reintervention.

This session explores leaflet modification techniques during TAVI, focusing on complex valve-in-valve procedures supported by artificial intelligence-powered planning and advanced imaging. Case discussions cover challenges such as low valve-to-coronary distances, bi-leaflet obstruction, and strategies to maintain coronary flow and hemodynamic stability.

A 65‑year‑old woman with obesity (BMI 38.7), prior cardiac surgery (CABG to OM and LAD in 2012), and chronic kidney disease presented with symptomatic severe mitral regurgitation (Carpentier type III: type IIIa due to calcification and type IIIb post‑MI) with moderately reduced LVEF (45%).

A transcatheter mitral...

This session highlights the evolving role of the pulmonary valve in adult structural interventions. It reviews complex transcatheter pulmonary valve replacement (TPVR) cases, strategies for managing challenging right ventricular outflow tract anatomies, and percutaneous solutions for pulmonary artery stenosis and related complications.

This session presents new techniques and practical tips in chronic total occlusion (CTO) percutaneous coronary intervention (PCI). It covers innovative approaches such as the side-flap technique, simplified antegrade strategies for calcified lesions, and retrograde CTO techniques, providing valuable insights into overcoming challenging occlusions.

This session explores new frontiers in transcatheter aortic valve implantation (TAVI) for treating pure aortic regurgitation. It addresses the challenges inherent to this indication, reviews treatment approaches using conventional balloon-expandable and self-expandable devices, and presents recent data along with dedicated TAVI devices designed specifically for aortic...

The COVID-19 pandemic caused huge disruption to healthcare services and dramatically reduced hospital admissions for MI.1 In response, the We CARE initiative was created from a collaboration between PCR and Stent – Save a Life! to rebuild patient confidence in pursuing timely medical treatment and to help...

The aims of We CARE are to rebuild patient confidence and help stakeholders provide effective and timely cardiac care through knowledge, education and training.

Paris, France. Since the start of the COVID-19 pandemic, patients have been consistently deprived of timely cardiovascular treatment. This is due in part to measures taken in response to the sanitary crisis, but it is also due to patients' own unwillingness to seek medical help, even...

Quantitative coronary angiography-guidance versus intravascular ultrasound-guidance for drug-eluting stent implantation (GUIDE-DES trial): A multicenter, non-inferiority, randomised-controlled trial

Nicola Ryan provides her take on the final results of GUIDE-DES which were presented by Taeoh Kim during the ESC 2023 congress in Amsterdam.

Note the assumptions in this article are based on the presentation...

Mirvat Alasnag provides her take on the CLEAR SYNERGY trial presented by Sanjit S Jolly at AHA 2024 in Chicago.

Nicola Ryan provides her take on the results of TAILORED-CHIP presented by Duk-Woo Park at the ESC Congress 2025 in Madrid.

Nicola Ryan provides her take on this clinical trial presented by Lisa Mielniczuk at the American College of Cardiology Scientific Session (ACC.23/WCC) – note this analysis is based upon the presented slides alone.

Nicola Ryan provides her take on the FULL REVASC trial which was presented at ACC.24 in Atlanta and published Simultaneously in NEJM.

The FULL REVASC trial is a multicentre registry-based randomised control trial comparing FFR-guided complete revascularisation of non-culprit lesions versus culprit lesion PCI alone in patients presenting...

Chiara De Biase provides her take on the results of AQUATIC presented by Martine Gilard at ESC Congress 2025 in Madrid.

Mirvat Alasnag provides her take on OPTION-STEMI, presented by Youngkeun Ahn at ESC Congress 2025 in Madrid.

Authored by Hector Garcia-Garcia and Jorge Sanz-Sanchez, this article examines pivotal randomized clinical trials on drug-coated balloons in coronary artery disease. It highlights their role in managing in-stent restenosis, de novo small vessel lesions, and large vessel lesions while exploring future directions through ongoing trials.