How to best identify and manage vulnerable plaque?

Hector Garcia-Garcia joins Salvatore Brugaletta in a discussion on the concept of vulnerable plaque, a key topic in contemporary cardiology. Together, they review the well-established definition of vulnerable plaque, characterised by high-risk features that predispose to rupture and cardiovascular events, and explore how advances in invasive and non-invasive imaging allow clinicians to identify these lesions in practice. The discussion also addresses the ongoing challenge of determining the best management strategy, emphasising the importance of treating not only the plaque but the overall vulnerable patient, while awaiting results from ongoing trials on potential focal therapies.

This interview was filmed at EuroPCR 2026: see more videos here.