Wall shear stress in BRS

EuroIntervention Journal

Read this study on early strut protrusion and late neointima thickness in the Absorb bioresorbable scaffold: a serial wall shear stress analysis up to 5 years

Bioresorbable scaffolds (BRS) have ushered interventional cardiology into a new era of percutaneous treatment of coronary artery disease. BRS restores vasomotricity and vessel wall (VW) cyclic strain that are vital for VW metabolism. Local haemodynamics (LH), quantified as wall shear stress (WSS), have fundamental interaction with the VW. Scaffold coverage, strut thickness, protrusion and embedment have an influence on local WSS distribution. Following scaffold implantation, disruption of laminar flow triggers a cascade of reactions that may result in acute/subacute thrombosis, chronic exuberant neointimal tissue (NTi) and neoatherosclerosis.

The aim of the study was to evaluate the effect of strut protrusion (SP) on wall shear stress (WSS) and neointimal growth (NG) one and five years after implantation of an Absorb bioresorbable vascular scaffold.

Read full article

Authors

E. Tenekecioglu, R. Torii, Y. Katagiri, T. Asano, R. Modolo, Y. Miyazaki, P. Chichareon, E. K.W. Poon, F. J.H. Gijsen, V. Thondapu, D. van Klaveren, H. Jonker, A. Ooi, P. Barlis, C. Collet, Y. Onuma, C. V. Bourantas, P. W. Serruys