PCR Journal Club

The PCR Journal Club provides a selection of Literature Reviews of top interventional cardiovascular journals world-wide, selected and commented by the PCR Journal Club team.

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Using the PICOT and SWOT methodologies to analyse clinical studies

04 Feb 2021

Clinical studies can be complex to interpret. By applying PICOT and SWOT to trial results, readers are encouraged to take ownership via logical methods to analyse and develop their critical thoughts on essential studies.

Transcatheter edge-to-edge repair for treatment of tricuspid regurgitation

05 Feb 2021

The purpose of this report was to study the 1-year outcomes with the TriClip transcatheter tricuspid valve repair system, including repair durability, clinical benefit and safety.

Reviewer

Salvatore Brugaletta
Transcatheter edge-to-edge repair for treatment of tricuspid regurgitation

Long-term safety of drug-coated devices for peripheral revascularisation

01 Feb 2021

In this large cohort, there was no evidence of increased long-term mortality following treatment with drug-coated devices. Read the review to find out more.

Reviewer

Ali Nazmi Calik

Ticagrelor versus clopidogrel in elective percutaneous coronary intervention (ALPHEUS): a randomised, open-label, phase 3b trial

27 Nov 2020

The ALPHEUS study sought to investigate whether more potent and rapid platelet inhibition properties of ticagrelor could reduce periprocedural atherothrombotic complications in chronic coronary syndrome patients undergoing high-risk PCI.

Reviewer

Ali Nazmi Calik
Ticagrelor versus clopidogrel in elective PCI (ALPHEUS)

Initial invasive versus conservative management of stable ischemic heart disease in patients with a history of heart failure or left ventricular dysfunction

03 Dec 2020

Insights from the ISCHEMIA Trial, commented by D. Milasinovic

Dejan Milasinovic

Reviewer

Dejan Milasinovic
Initial invasive vs conservative management of stable ischemic heart disease in patients with a history of heart failure or left ventricular dysfunction

Percutaneous coronary intervention for vulnerable coronary atherosclerotic plaque

30 Nov 2020

Do you have any experience with NIRS technology? Do you think that use of 3rd generation DES would have shown better results than BVS? Read this review by S. Brugaletta

Reviewer

Salvatore Brugaletta
PCI for vulnerable coronary atherosclerotic plaque

The EURO SHOCK Trial: Design, aims and objectives

19 Nov 2020

Randomised comparison of extra corporeal membrane oxygenation (ECMO) delivered after acute-PCI plus standard of care versus standard of care alone after acute PCI, in patients presenting with ACS and cardiogenic shock

Dr. Mirvat Alasnag

Reviewer

Mirvat Alasnag
The EURO SHOCK Trial: Design, aims and objectives

Aspirin-free prasugrel monotherapy following coronary artery stenting in patients with stable CAD

27 Oct 2020

The ASET pilot study: a multicenter, single-arm, first-in-human and proof-of-concept trial which included a total of 212 low-risk patients with stable coronary artery disease

Reviewer

Ali Nazmi Calik
Aspirin-free prasugrel monotherapy following coronary artery stenting in patients with stable CAD

Association of intra-arrest transport vs continued on-scene resuscitation with survival to hospital discharge among patients with out-of-hospital cardiac arrest (OHCA)

04 Nov 2020

This multicentre time-dependent propensity score–matched cohort study was designed to evaluate the impact of intra-arrest transport as compared to continued on-scene resuscitationon survival to hospital discharge among patients experiencing out-of-hospital cardiac arrest.

Luigi Biasco

Reviewer

Luigi Biasco
Gregorio Tersalvi

Reviewer

Gregorio Tersalvi
Association of intra-arrest transport vs continued on-scene resuscitation with survival to hospital discharge among patients with out-of-hospital cardiac arrest

Arterial lactate in cardiogenic shock: Prognostic value of clearance versus single values

15 Oct 2020

This subanalysis of the IABP-SHOCK study shows how a negative trial, when properly conducted, can generate useful hypothesis-generating information with relevant clinical impact. Find out more!

Luigi Biasco

Reviewer

Luigi Biasco
Arterial lactate in cardiogenic shock: Prognostic value of clearance vs single values