300 results
Cangrelor, Tirofiban and Chewed or Standard Prasugrel Regimens in Patients with ST-Segment Elevation Myocardial Infarction: Primary Results of the FABOLUS FASTER Trial
15 Jul 2020
The results of the FABOLUS FASTER trial clearly highlight that a high residual platelet reactivity persists when targeting platelet activation by inhibition of the P2Y12 receptor either with Prasugrel or Cangrelor, while tackling the mechanism of platelet adhesion thought the inhibition of GPIIB/IIIA might almost completely...
Reviewer
Multivessel versus culprit-only revascularisation in STEMI and multivessel coronary artery disease: meta-analysis of randomised trials
23 Jul 2020
The current meta-analysis study sought to evaluate contemporary randomized trials on multivessel versus IRA-only PCI in patients presenting with STEMI and multivessel CAD.
Reviewer
Multicentre, randomised comparison of two-stent and provisional stenting techniques in patients with complex coronary bifurcation lesions: the DEFINITION II trial
22 Jul 2020
DEFINITION-II adds to the evidence that an upfront 2-stent strategy may be most appropriate in true complex bifurcation lesions.
Reviewer
Intravascular healing is not affected by approaches in contemporary CTO PCI: the CONSISTENT CTO study
16 Jul 2020
This study compares clinical, angiographic and imaging outcomes of patients undergoing CTO PCI with dissection and re-entry techniques (DART) and subintimal stenting to intimal techniques.
Reviewer
Subcutaneous selatogrel inhibits platelet aggregation in patients with acute myocardial infarction
07 Jul 2020
This study sought to assess the antiplatelet response to selatogrel, a novel subcutaneous reversible P2Y12 receptor antagonist, in patients with AMI.
Reviewer
Reviewer
Clinical outcomes following coronary bifurcation PCI techniques: a systematic review and network meta-analysis comprising 5,711 patients
07 Jul 2020
The main message of this study is that DK-crush was associated with fewer MACE, driven by lower rates of repeat revascularisation, whereas no significant differences among techniques were observed for cardiac death, myocardial infarction and stent thrombosis.
Reviewer
Randomised comparison of the polymer-free biolimus-coated BioFreedom stent with the ultrathin strut biodegradable polymer sirolimus-eluting Orsiro stent in an all-comers population treated with PCI: the SORT OUT IX Trial
03 Jul 2020
While investigations testing differences in efficacy and safety between drug-eluting stents according to the characteristics of the coating – durable, bioresorbable, or polymer-free – have shown mixed results, several studies have highlighted the benefit of implanting a device with thinner strut.
Reviewer
Effect of ticagrelor monotherapy vs ticagrelor with aspirin on major bleeding and cardiovascular events in patients with acute coronary syndrome : the TICO randomised clinical trial
02 Jul 2020
The outstanding results of the TICO trial have to be interpreted in light of a number of considerations and the generalisability of its results in other contexts requires further analysis.
Reviewer
Impella versus extracorporeal membrane oxygenation for acute myocardial infarction cardiogenic shock
23 Jun 2020
This study aims at evaluating the difference in baseline characteristics, procedural and clinical outcomes in those receiving Impella or ECMO in the United States in the setting of AMI and CS.
Reviewer
Reviewer
Left atrial appendage closure versus direct oral anticoagulants in high-risk patients with atrial fibrillation
23 Jun 2020
Although the main finding of the PRAGUE-17 study was of no differences between the two groups in terms of the composite primary endpoint or significant bleeding, there are some other important points to consider.
Reviewer
