295 results
Clinical outcomes of proximal optimization technique (POT) in bifurcation stenting
22 Jun 2021
Find out more about what is considered the largest real-world registry data permitting analysis of very specific steps of bifurcation stenting, POT, and KBI.

Reviewer

Reviewer

Aspirin versus clopidogrel for chronic maintenance monotherapy after percutaneous coronary intervention (HOST-EXAM): an investigator-initiated, prospective, randomised, open-label, multicentre trial
18 Jun 2021
The HOST-EXAM trial sought to define whether, after DAPT for PCI with DES, clopidogrel monotherapy is associated with improved outcomes compared with aspirin monotherapy.

Reviewer

Effect of CYP2C19 genotype on ischemic outcomes during oral P2Y12 inhibitor therapy: a meta-analysis
14 Jun 2021
Read more about this systematic review and meta-analysis which looked to ascertain if there is benefit in individualizing anti-platelet therapy on the basis of the CYP2C19 genotype.
Reviewer

Reviewer

Moderate aortic stenosis in patients with heart failure and reduced ejection fraction
08 Jun 2021
The aim of this study was to determine the prognostic impact conferred by the presence of moderate AS on the outcomes of patients with HFrEF.

Reviewer

External applicability of the ISCHEMIA trial: an analysis of a prospective nationwide registry of patients with stable coronary artery disease
03 Jun 2021
This study aimed to delineate the external validity of the ISCHEMIA trial by applying the ISCHEMIA inclusion and exclusion criteria to an established cohort of patients with stable coronary disease in an observational setting.
Reviewer

Reviewer

EBC MAIN Late-breaking trial analysis
13 Jun 2021
Examination of the study methodology and results according to the PICOT principle, SWOT analysis and real-world applicability of the EBC MAIN trial presented at EuroPCR 2021.

Cardiac mortality in patients randomised to elective coronary revascularisation plus medical therapy or medical therapy alone: a systematic review and meta-analysis
01 Jun 2021
The value of elective coronary revascularisation plus medical therapy over medical therapy alone in managing stable patients with coronary artery disease is debated. Hence, the authors reviewed all trials comparing the two strategies in this population to appraise whether revascularisation in addition to medical therapy affects...

Reviewer

Sex differences among patients with high risk receiving Ticagrelor with or without Aspirin after percutaneous coronary intervention: a subgroup analysis of the TWILIGHT randomized clinical trial
28 May 2021
This is a prespecified secondary sub-analysis of the TWILIGHT trial that seeks to shed light on the association of the different baseline risk factors, namely advanced age and significant renal dysfunction, with a higher bleeding risk in women.

Reviewer

Reviewer

Kidney Transplant List Status and Outcomes in the ISCHEMIA-CKD Trial
27 May 2021
ISCHEMIA-CKD is the only contemporary randomized trial that prospectively evaluated an upfront strategy of coronary angiography and revascularization plus optimal medical therapy (OMT) compared with OMT alone in patients listed for renal transplant.

Reviewer

Multivessel PCI Guided by FFR or Angiography for Myocardial Infarction - FLOWER-MI
26 May 2021
This investigator-initiated randomised, open-label, multicentre trial compares FFR versus angiography guided strategies for treating non-culprit lesions in patients presenting with STEMI and multivessel coronary artery disease. The results of this study were released during ACC.21.

Reviewer

Reviewer
