PCR Journal Club

The PCR Journal Club provides a selection of Literature Reviews of top interventional cardiovascular journals world-wide, selected and commented by the PCR Journal Club team.

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300 results

Thin-cap fibroatheroma predicts clinical events in diabetic patients with normal fractional flow reserve: the COMBINE OCT–FFR trial

16 Aug 2021

The aim of this study was to understand the impact of optical coherence tomography (OCT)-detected thin-cap fibroatheroma (TCFA) on clinical outcomes of diabetes mellitus (DM) patients with fractional flow reserve (FFR)-negative lesions.

M. Pighi

Reviewer

Michele Pighi

Reviewer

Salvatore Brugaletta
Simone Fezzi

Reviewer

Simone Fezzi
Thin-cap fibroatheroma predicts clinical events in diabetic patients with normal fractional flow reserve: the COMBINE OCT–FFR trial

Optical coherence tomography to guide percutaneous coronary intervention of the left main coronary artery: the LEMON study

08 Jul 2021

The aim of the LEMON study was to assess the applicability of a predefined standardized protocol, which included three OCT runs.

Reviewer

Mila Kovacevic
Dejan Milasinovic

Reviewer

Dejan Milasinovic
OCT to guide PCI of LMCA: the LEMON study

In-Stent CTO percutaneous coronary intervention: individual patient data pooled analysis of 4 multicenter registries

12 Aug 2021

This analysis highlights that, in appropriate hands, ISR CTO-PCI is safe, with similar success rates to de-novo CTO-PCI.

Nicola Ryan

Reviewer

Nicola Ryan
Central Illustration : In-stent restenosis chronic total occlusion percutaneous coronary intervention

Operator volumes and in-hospital outcomes: an analysis of 7,740 rotational atherectomy procedures from the BCIS national database

05 Jul 2021

Find out more about the results of this analysis which suggest that operator experience may be an important effect modifier in ROTA-PCI.

Nicola Ryan

Reviewer

Nicola Ryan
Operator volumes and in-hospital outcomes: an analysis of 7,740 rotational atherectomy procedures from the BCIS national database

Eight-year outcomes for patients with aortic valve stenosis at low surgical risk randomized to transcatheter vs. surgical aortic valve replacement

09 Jul 2021

Read more about the Nordic Aortic Valve Intervention (NOTION) trial to compare clinical outcomes and durability of bioprosthetic aortic valves 8 years after TAVI and SAVR.

Reviewer

Salvatore Brugaletta
Eight-year outcomes for patients with aortic valve stenosis at low surgical risk randomized to transcatheter vs. surgical aortic valve replacement

Clinical outcomes of proximal optimization technique (POT) in bifurcation stenting

22 Jun 2021

Find out more about what is considered the largest real-world registry data permitting analysis of very specific steps of bifurcation stenting, POT, and KBI.

Dr. Mirvat Alasnag

Reviewer

Mirvat Alasnag
Khaled F. Al-Shaibi

Reviewer

Khaled Al-Shaibi
Clinical outcomes of proximal optimization technique (POT) in bifurcation stenting

Aspirin versus clopidogrel for chronic maintenance monotherapy after percutaneous coronary intervention (HOST-EXAM): an investigator-initiated, prospective, randomised, open-label, multicentre trial

18 Jun 2021

The HOST-EXAM trial sought to define whether, after DAPT for PCI with DES, clopidogrel monotherapy is associated with improved outcomes compared with aspirin monotherapy.

Daniele Giacoppo

Reviewer

Daniele Giacoppo
Aspirin vs clopidogrel for chronic maintenance monotherapy after PCI: HOST-EXAM trial

Effect of CYP2C19 genotype on ischemic outcomes during oral P2Y12 inhibitor therapy: a meta-analysis

14 Jun 2021

Read more about this systematic review and meta-analysis which looked to ascertain if there is benefit in individualizing anti-platelet therapy on the basis of the CYP2C19 genotype. 

Reviewer

Samuel Mcgrath
Kalpa De Silva

Reviewer

Kalpa De Silva
Effect of CYP2C19 genotype on ischemic outcomes during oral P2Y12 inhibitor therapy: a meta-analysis

Moderate aortic stenosis in patients with heart failure and reduced ejection fraction

08 Jun 2021

The aim of this study was to determine the prognostic impact conferred by the presence of moderate AS on the outcomes of patients with HFrEF.

Luigi Biasco

Reviewer

Luigi Biasco
Moderate aortic stenosis in patients with heart failure and reduced ejection fraction

External applicability of the ISCHEMIA trial: an analysis of a prospective nationwide registry of patients with stable coronary artery disease

03 Jun 2021

This study aimed to delineate the external validity of the ISCHEMIA trial by applying the ISCHEMIA inclusion and exclusion criteria to an established cohort of patients with stable coronary disease in an observational setting.

Reviewer

Rupert Simpson
Kalpa De Silva

Reviewer

Kalpa De Silva
External applicability of the ISCHAEMIA trial: an analysis of a prospective nationwide registry of patients with stable coronary artery disease