300 results
Thin-cap fibroatheroma predicts clinical events in diabetic patients with normal fractional flow reserve: the COMBINE OCT–FFR trial
16 Aug 2021
The aim of this study was to understand the impact of optical coherence tomography (OCT)-detected thin-cap fibroatheroma (TCFA) on clinical outcomes of diabetes mellitus (DM) patients with fractional flow reserve (FFR)-negative lesions.

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Optical coherence tomography to guide percutaneous coronary intervention of the left main coronary artery: the LEMON study
08 Jul 2021
The aim of the LEMON study was to assess the applicability of a predefined standardized protocol, which included three OCT runs.

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In-Stent CTO percutaneous coronary intervention: individual patient data pooled analysis of 4 multicenter registries
12 Aug 2021
This analysis highlights that, in appropriate hands, ISR CTO-PCI is safe, with similar success rates to de-novo CTO-PCI.

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Operator volumes and in-hospital outcomes: an analysis of 7,740 rotational atherectomy procedures from the BCIS national database
05 Jul 2021
Find out more about the results of this analysis which suggest that operator experience may be an important effect modifier in ROTA-PCI.

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Eight-year outcomes for patients with aortic valve stenosis at low surgical risk randomized to transcatheter vs. surgical aortic valve replacement
09 Jul 2021
Read more about the Nordic Aortic Valve Intervention (NOTION) trial to compare clinical outcomes and durability of bioprosthetic aortic valves 8 years after TAVI and SAVR.

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Clinical outcomes of proximal optimization technique (POT) in bifurcation stenting
22 Jun 2021
Find out more about what is considered the largest real-world registry data permitting analysis of very specific steps of bifurcation stenting, POT, and KBI.

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Aspirin versus clopidogrel for chronic maintenance monotherapy after percutaneous coronary intervention (HOST-EXAM): an investigator-initiated, prospective, randomised, open-label, multicentre trial
18 Jun 2021
The HOST-EXAM trial sought to define whether, after DAPT for PCI with DES, clopidogrel monotherapy is associated with improved outcomes compared with aspirin monotherapy.

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Effect of CYP2C19 genotype on ischemic outcomes during oral P2Y12 inhibitor therapy: a meta-analysis
14 Jun 2021
Read more about this systematic review and meta-analysis which looked to ascertain if there is benefit in individualizing anti-platelet therapy on the basis of the CYP2C19 genotype.
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Moderate aortic stenosis in patients with heart failure and reduced ejection fraction
08 Jun 2021
The aim of this study was to determine the prognostic impact conferred by the presence of moderate AS on the outcomes of patients with HFrEF.

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External applicability of the ISCHEMIA trial: an analysis of a prospective nationwide registry of patients with stable coronary artery disease
03 Jun 2021
This study aimed to delineate the external validity of the ISCHEMIA trial by applying the ISCHEMIA inclusion and exclusion criteria to an established cohort of patients with stable coronary disease in an observational setting.
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