Christian Frerker
Latest contributions
Cardiovalve hits the TARGET: advancing transcatheter valve replacement
18 Nov 2025 – From PCR London Valves 2025
This session highlights the features and procedural steps of the next-generation Cardiovalve systems for tricuspid and mitral valve replacement. It reviews interim results from the TARGET study, emphasizing echocardiographic findings and reverse remodeling effects, and discusses best practices for patient selection and the learning pathway to...
Challenging mitral interventions
18 Nov 2025 – From PCR London Valves 2025
This session explores the complexities of mitral interventions, highlighting advancements and challenges in transcatheter mitral valve repair (TMVR). Topics include the benefits of a simplified single-step TMVR approach, the influence of hemodynamic parameters on MitraClip therapy outcomes, strategies for managing persistent pulmonary oedema, and approaches to...
Align for the future with next gen Myval transcatheter heart valve series
16 Nov 2025 – From PCR London Valves 2025
Discover how the latest Myval transcatheter heart valve (THV) innovations are shaping TAVI outcomes. This PCR London Valves 2025 session highlights the clinical evidence behind the next-gen Myval THV series, best practices for implantation, and upcoming innovations set to improve patient care. Learn step-by-step techniques for deploying Myval...
A simple maneuver to track the wire during a transseptal mitral valve-in-valve procedure
05 Nov 2025
Advancing a transcatheter heart valve through the septostomy can be tricky, with the wire sometimes prolapsing into the left atrium.
This step-by-step tutorial demonstrates a simple yet effective maneuver that allows smooth, controlled navigation from the right atrium to the mitral position, ensuring precise valve deployment.

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Best of science and education in cardiovascular interventional medicine in 2024
16 Dec 2024
Dear Colleagues, dear PCR Companions,
As we welcome a new year, it is the perfect time to reflect on what we achieved together over the past year—both as a celebration of our successes and as motivation to continue improving in the year ahead.
2024 was a record year...
How should I treat a torrential tricuspid valve regurgitation with large coaptation gap size and severe tethered leaflets?
26 Nov 2024
An 84-year-old female patient with severe tricuspid valve regurgitation (TR) and progressive right-sided heart failure signs is referred for diagnosis and treatment. Transoesophageal echocardiography (TEE) reveals isolated torrential TR (5/5) with a large coaptation gap size and tethered leaflets. How would you treat this patient?

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