
Darren Mylotte
Latest contributions
Bicuspid disease - All you need to know
16 May 2024 – From EuroPCR 2024
This session is ideal if you want to understand the anatomical features of bicuspid aortic stenosis, learn about the latest post-TAVI clinical outcomes in bicuspid aortic valves, grasp key considerations for TAVI sizing in these cases, and analyze both self-expanding and balloon-expandable TAVI procedures in bicuspid...

Contemporary TAVI: the VISION of lifetime management
15 May 2024 – From EuroPCR 2024
In this session, discover how pre-procedural assessment is used to optimize procedural outcomes, ensuring the best possible results for patients undergoing TAVI, learn the intricacies of selecting the most suitable valve for each individual patient, considering their unique anatomical and clinical factors, and engage in discussions...

Planning for a lifetime starts with choosing the right valve first: from first TAVI to redo-TAVI
15 May 2024 – From EuroPCR 2024
Watch this session to learn the best practices for treating aortic stenosis, with a focus on lifetime management. Gain insights into evaluating patient anatomy and clinical presentation to anticipate the need for a second valve, understand different valve designs and their initial selection, and observe a...

Crossing the finishing line - Latest best practices and technologies for large hole arterial and venous closure
14 May 2024 – From EuroPCR 2024
Tune in to this session for insights on optimizing vascular access and closure techniques. Explore steps like thorough CT analysis, ultrasound-guided puncture, and contingency plans for alternative access methods to minimize complications. Discover a novel patch-based closure approach offering immediate hemostasis and simplified usage, addressing issues...

TAVI in TAVI - LIVE case
14 May 2024 – From EuroPCR 2024
A 74-year-old male with a history of cancer, TAVI with Evolut R 34 in 2019, COPD, obesity, and RBBB presents with a symptomatic degenerated valve (regurgitation).
It was decided to implant a Sapien 3 Ultra 26, without pre-dilatation and post-dilatation, using a temporary pacing lead (due to...

What is the optimal aortic valve choice in the younger patient: transcatheter or surgery?
29 Nov 2023 – From PCR London Valves 2023
Follow the discussion between Darren Mylotte, Kentaro Hayashida and Ole De Backer to better understand the concept of "young patients" and what it exactly implies, and analyze how best to bring these specific patients to the end of their still potentially long life, by choosing the...

Finishing strong - Latest best practices and technologies for large hole arterial and venous closure
21 Nov 2023 – From PCR London Valves 2023
Consult this session to grasp the current landscape of techniques for closing large holes in both arterial and venous contexts. Acquire valuable tips and tricks aimed at minimizing vascular complications, and learn about the innovative patch-based closure approach for a comprehensive understanding.

VitaFlow - The electrically enable self-expanding TAVI valve
21 Nov 2023 – From PCR London Valves 2023
This session provides insights into the unique design and advantages of VitaFlow Liberty for TAVI. It covers techniques to minimize microdislodgement during the procedure, identifies situations and patient types most suitable for VitaFlow Liberty, and reviews early clinical results associated with this technology.

Key questions in aortic valve intervention - How to navigate valve sequencing in younger patients?
21 Nov 2023 – From PCR London Valves 2023
What are the aspects to consider when treating younger patients? In this session, get both the interventional cardiologist's and the surgeon's perspective. What do we know and what do we need to know about valve sequencing and hemodynamics? What about CT planning and execution of redo-TAVI?...

TAVI - stroke
20 Nov 2023 – From PCR London Valves 2023
Join this session for key perspectives on stroke management and prevention in TAVI: gain a comprehensive view of the long-term outcomes in transfemoral TAVI complicated by stroke, evaluate a novel cerebral embolic protection during TAVI through the PROTEMBO C-TRIAL, learn how TAVR debris captured by CEP...

Defying complexity: achieving optimal TAVI procedural outcomes in challenging anatomies with the new Evolut FX
20 Nov 2023 – From PCR London Valves 2023
Watch this session to understand factors to consider when deciding on valve selection, recognize the significance of device choice and implantation technique in redo-TAVI, and acquire insights into anticipating challenges associated with implanting a bicuspid valve, large anatomy, and a horizontal aorta.

Challenging TAVI cases
19 Nov 2023 – From PCR London Valves 2023
This PCR London Valves 2023 session aims to analyse some of the complex aspects of TAVI by looking at challenging clinical and anatomical scenarios to enable you to learn how to manage potential complications by learning about innovative strategies and exploring different approaches.

The Top Late-Breaking Trials: TRISCEND II, TRILUMINATE at 3 years, EuroSMR score, CLASP IID, OPERA-TAVI...
19 Nov 2023 – From PCR London Valves 2023
Discover the top late-breaking trials which were presented during PCR London Valves 2023:
- TRISCEND II: A randomised trial of transcatheter tricuspid valve replacement vs medical therapy
- Percutaneous edge-to-edge repair for tricuspid regurgitation: TRILUMINATE trial three-year outcomes
- Transcatheter mitral valve-in-valve vs. redo surgical replacement for degenerated bioprostheses
- Artificial intelligence derived risk...

Cerebral embolic protection during TAVI: evidence meets practice
11 Nov 2023
Watch the replay of this webinar with D. Mylotte, C. Cook and R. Kharbanda to know more about the incidence and impact of TAVI associated stroke and much more!

Transcatheter bicuspid valve replacement: LIVE Case from Institut Cardiovasculaire Paris Sud, Massy - France
18 May 2023 – From EuroPCR 2023
Discover tips for TAVI and analyse CT findings to optimise procedural outcomes in bicuspid anatomy.

Cutting-edge technologies: clinical updates on TES, BRS, TAVR and LAA closure
17 May 2023 – From EuroPCR 2023
Watch this session to find out more about the three-year outcomes of the FUTURE-II Trial, the TARGET clinical trial roadmap, the TARGET IV NA Trial update, the twelve-month outcomes of the SAVE PROTECT Trial, and the quantitative aortographic assessment of regurgitation in patients treated with VitaFlow.

Selecting the right first valve to secure lifetime management
17 May 2023 – From EuroPCR 2023
The treatment of young and less at-risk patients clearly shows that their age, life expectancy and risk factors are essential parameters to be taken into account in the choice of TAVI and therefore it is essential to think about future coronary access after TAVI. Watch the...

EuroPCR 2023 Hotlines / Late-Breaking Trials: TAVI
16 May 2023 – From EuroPCR 2023
Discover the conclusions of various studies and registries about TAVI: 5-year outcomes with the ACURATE neo2 valve: the Neo AS CE-mark study; TAVR in patients with cardiogenic shock which evaluated outcomes of consecutive TAVRs in patients with CS using contemporary SAPIEN 3 and SAPIEN 3 ultra...

TAVI in patients with heavily calcified aortic root
19 Feb 2023 – From PCR Tokyo Valves 2023
What role does TAVI play in patients' severely calcified roots? Study the use of balloon-expandable devices, assessing the impact of calcification on aortic root rupture, strategies for safe and effective procedures, and when to consider surgical AVR.
TAVI in small annulus and coronary artery disease - Session with LIVE case
19 Feb 2023 – From PCR Tokyo Valves 2023
Watch the complex case of an 84-year-old woman with hypertension, type 2 diabetes and coronary artery disease who presented with worsening NYHA class II-III exertional dyspnoea, but no angina, and find out how she was treated LIVE.

Predictability and control: Evolut procedural approaches
18 Feb 2023 – From PCR Tokyo Valves 2023
In this session, delve into Evolut procedural approaches. You will be examining the cusp overlap technique, its latest clinical data and outcomes of the Medtronic's newest generational technology: Evolut FX.
Imaging for aortic valve interventions
17 Feb 2023 – From PCR Tokyo Valves 2023
In this session, review the anatomy of the aortic valve system, learn how to assess low-flow, low-gradient severe AS, identify the pitfalls to avoid when assessing paravalvular leakage after TAVI, and find out more about how to detect valve thrombosis and degeneration, among others!

The VitaFlow TAVI system - A new device that delivers exceptional patient outcomes
29 Nov 2022 – From PCR London Valves 2022
In this session, a panel of experts introduce the VitaFlow TAVI system, a good option for patients with complex anatomies. They also present the five-year results of VitaFlow in severe aortic stenosis.

Maintaining selective coronary access after TAVI and re-do TAVI procedures
28 Nov 2022 – From PCR London Valves 2022
Watch this session if you want to understand the various challenges when trying to get coronary access after TAVI, learn different techniques and discuss the options for coronary access after re-do TAVI.

Challenging scenarios: TAV-in-TAV procedures
28 Nov 2022 – From PCR London Valves 2022
Consult this session to discover some challenging TAV-in-TAV procedures, and learn more about the key role of imaging during pre-procedural work-up and the potential treatment options after TAVI bioprosthetic valve fracture.

Patient-prosthesis mismatch: surgical and transcatheter approaches - LIVE case
28 Nov 2022 – From PCR London Valves 2022
Consult this session to discover different surgical and transcatheter approaches:
- Part 1: Bioprosthesis aortic valve stenosis
A 73-year-old male, with diabetes, BMI 29, atrial fibrillation, history of SAVR 15 years ago (Perimount 27) presents a symptomatic severe surgical valve stenosis with a preserved LV function.
During the live time...

Innovations in transcatheter tricuspid valve intervention - LIVE case
28 Nov 2022 – From PCR London Valves 2022
Watch two very innovative tricuspid cases you've never seen before:
- Part 1: TR replacement
An 82-year-old male with chronic atrial fibrillation and completely PM dependent for 27 years, presents a symptomatic torrential TR and an enlarged annulus with a great gap. The operators implanted for the first time in...

Create the future of TAVI - Optimisation of the procedure and patient pathway
27 Nov 2022 – From PCR London Valves 2022
Dive into this session to discover what can be improved today to be ready to treat future TAVI patient volumes. You'll also learn how to set up a successful TAVI coordinating team and adopt it in your hospital, and how to create a win-win partnership with...

Ensuring optimal TAVI outcomes - LIVE case
27 Nov 2022 – From PCR London Valves 2022
A 75-year-old female with diabetes and history of ischemic stroke 5 years ago presents a symptomatic severe aortic valve stenosis in a small annulus.
After pre-dilatation (18 mm balloon), the operators implant an Acurate neo2 23 mm with a sentinel cerebral embolic protection device. Watch them perform...

How and when should I consider Drug Coated Balloons to treat de novo lesions?
31 Oct 2022
Discover the replay of this PCR Webinar on Drug Coated Balloons with F. Ribichini, F. Manterola and D. Mylotte.
