Dr. Darren Mylotte

Darren Mylotte

Interventional cardiologist / Cardiologist
University Hospitals Galway - Galway, Ireland

Latest contributions

Bicuspid disease - All you need to know

16 May 2024 – From EuroPCR 2024

This session is ideal if you want to understand the anatomical features of bicuspid aortic stenosis, learn about the latest post-TAVI clinical outcomes in bicuspid aortic valves, grasp key considerations for TAVI sizing in these cases, and analyze both self-expanding and balloon-expandable TAVI procedures in bicuspid...

Bicuspid disease - All you need to know

Contemporary TAVI: the VISION of lifetime management

15 May 2024 – From EuroPCR 2024

In this session, discover how pre-procedural assessment is used to optimize procedural outcomes, ensuring the best possible results for patients undergoing TAVI, learn the intricacies of selecting the most suitable valve for each individual patient, considering their unique anatomical and clinical factors, and engage in discussions...

Contemporary TAVI: the VISION of lifetime management

Planning for a lifetime starts with choosing the right valve first: from first TAVI to redo-TAVI

15 May 2024 – From EuroPCR 2024

Watch this session to learn the best practices for treating aortic stenosis, with a focus on lifetime management. Gain insights into evaluating patient anatomy and clinical presentation to anticipate the need for a second valve, understand different valve designs and their initial selection, and observe a...

Planning for a lifetime starts with choosing the right valve first: from first TAVI to redo-TAVI

Crossing the finishing line - Latest best practices and technologies for large hole arterial and venous closure

14 May 2024 – From EuroPCR 2024

Tune in to this session for insights on optimizing vascular access and closure techniques. Explore steps like thorough CT analysis, ultrasound-guided puncture, and contingency plans for alternative access methods to minimize complications. Discover a novel patch-based closure approach offering immediate hemostasis and simplified usage, addressing issues...

Crossing the finishing line - Latest best practices and technologies for large hole arterial and venous closure

TAVI in TAVI - LIVE case

14 May 2024 – From EuroPCR 2024

A 74-year-old male with a history of cancer, TAVI with Evolut R 34 in 2019, COPD, obesity, and RBBB presents with a symptomatic degenerated valve (regurgitation).
It was decided to implant a Sapien 3 Ultra 26, without pre-dilatation and post-dilatation, using a temporary pacing lead (due to...

TAVI for degenerated aortic bioprosthesis

What is the optimal aortic valve choice in the younger patient: transcatheter or surgery?

29 Nov 2023 – From PCR London Valves 2023

Follow the discussion between Darren Mylotte, Kentaro Hayashida and Ole De Backer to better understand the concept of "young patients" and what it exactly implies, and analyze how best to bring these specific patients to the end of their still potentially long life, by choosing the...

What is the optimal aortic valve choice in the younger patient: transcatheter or surgery?

Finishing strong - Latest best practices and technologies for large hole arterial and venous closure

21 Nov 2023 – From PCR London Valves 2023

Consult this session to grasp the current landscape of techniques for closing large holes in both arterial and venous contexts. Acquire valuable tips and tricks aimed at minimizing vascular complications, and learn about the innovative patch-based closure approach for a comprehensive understanding.

Finishing strong - Latest best practices and technologies for large hole arterial and venous closure

VitaFlow - The electrically enable self-expanding TAVI valve

21 Nov 2023 – From PCR London Valves 2023

This session provides insights into the unique design and advantages of VitaFlow Liberty for TAVI. It covers techniques to minimize microdislodgement during the procedure, identifies situations and patient types most suitable for VitaFlow Liberty, and reviews early clinical results associated with this technology.

VitaFlow - The electrically enable self-expanding TAVI valve

Key questions in aortic valve intervention - How to navigate valve sequencing in younger patients?

21 Nov 2023 – From PCR London Valves 2023

What are the aspects to consider when treating younger patients? In this session, get both the interventional cardiologist's and the surgeon's perspective. What do we know and what do we need to know about valve sequencing and hemodynamics? What about CT planning and execution of redo-TAVI?...

Key questions in aortic valve intervention - How to navigate valve sequencing in younger patients?

TAVI - stroke

20 Nov 2023 – From PCR London Valves 2023

Join this session for key perspectives on stroke management and prevention in TAVI: gain a comprehensive view of the long-term outcomes in transfemoral TAVI complicated by stroke, evaluate a novel cerebral embolic protection during TAVI through the PROTEMBO C-TRIAL, learn how TAVR debris captured by CEP...

TAVI - stroke

Defying complexity: achieving optimal TAVI procedural outcomes in challenging anatomies with the new Evolut FX

20 Nov 2023 – From PCR London Valves 2023

Watch this session to understand factors to consider when deciding on valve selection, recognize the significance of device choice and implantation technique in redo-TAVI, and acquire insights into anticipating challenges associated with implanting a bicuspid valve, large anatomy, and a horizontal aorta.

Defying complexity: achieving optimal TAVI procedural outcomes in challenging anatomies with the new Evolut FX

Challenging TAVI cases

19 Nov 2023 – From PCR London Valves 2023

This PCR London Valves 2023 session aims to analyse some of the complex aspects of TAVI by looking at challenging clinical and anatomical scenarios to enable you to learn how to manage potential complications by learning about innovative strategies and exploring different approaches.

Challenging TAVI cases

The Top Late-Breaking Trials: TRISCEND II, TRILUMINATE at 3 years, EuroSMR score, CLASP IID, OPERA-TAVI...

19 Nov 2023 – From PCR London Valves 2023

Discover the top late-breaking trials which were presented during PCR London Valves 2023:

  • TRISCEND II: A randomised trial of transcatheter tricuspid valve replacement vs medical therapy
  • Percutaneous edge-to-edge repair for tricuspid regurgitation: TRILUMINATE trial three-year outcomes
  • Transcatheter mitral valve-in-valve vs. redo surgical replacement for degenerated bioprostheses
  • Artificial intelligence derived risk...
PCR London Valves 2023 Top Late-Breaking Trials

Cerebral embolic protection during TAVI: evidence meets practice

11 Nov 2023

Watch the replay of this webinar with D. Mylotte, C. Cook and R. Kharbanda to know more about the incidence and impact of TAVI associated stroke and much more!

Transcatheter bicuspid valve replacement: LIVE Case from Institut Cardiovasculaire Paris Sud, Massy - France

18 May 2023 – From EuroPCR 2023

Discover tips for TAVI and analyse CT findings to optimise procedural outcomes in bicuspid anatomy.

Transcatheter bicuspid valve replacement: LIVE Case from Institut Cardiovasculaire Paris Sud, Massy - France

Cutting-edge technologies: clinical updates on TES, BRS, TAVR and LAA closure

17 May 2023 – From EuroPCR 2023

Watch this session to find out more about the three-year outcomes of the FUTURE-II Trial, the TARGET clinical trial roadmap, the TARGET IV NA Trial update, the twelve-month outcomes of the SAVE PROTECT Trial, and the quantitative aortographic assessment of regurgitation in patients treated with VitaFlow.

Selecting the right first valve to secure lifetime management

17 May 2023 – From EuroPCR 2023

The treatment of young and less at-risk patients clearly shows that their age, life expectancy and risk factors are essential parameters to be taken into account in the choice of TAVI and therefore it is essential to think about future coronary access after TAVI. Watch the...

EuroPCR 2023 Hotlines / Late-Breaking Trials: TAVI

16 May 2023 – From EuroPCR 2023

Discover the conclusions of various studies and registries about TAVI: 5-year outcomes with the ACURATE neo2 valve: the Neo AS CE-mark study; TAVR in patients with cardiogenic shock which evaluated outcomes of consecutive TAVRs in patients with CS using contemporary SAPIEN 3 and SAPIEN 3 ultra...

TAVI Hotlines EuroPCR2023

TAVI in patients with heavily calcified aortic root

19 Feb 2023 – From PCR Tokyo Valves 2023

What role does TAVI play in patients' severely calcified roots? Study the use of balloon-expandable devices, assessing the impact of calcification on aortic root rupture, strategies for safe and effective procedures, and when to consider surgical AVR.

TAVI in small annulus and coronary artery disease - Session with LIVE case

19 Feb 2023 – From PCR Tokyo Valves 2023

Watch the complex case of an 84-year-old woman with hypertension, type 2 diabetes and coronary artery disease who presented with worsening NYHA class II-III exertional dyspnoea, but no angina, and find out how she was treated LIVE.

TAVI in small annulus and CAD

Predictability and control: Evolut procedural approaches

18 Feb 2023 – From PCR Tokyo Valves 2023

In this session, delve into Evolut procedural approaches. You will be examining the cusp overlap technique, its latest clinical data and outcomes of the Medtronic's newest generational technology: Evolut FX. 

Imaging for aortic valve interventions

17 Feb 2023 – From PCR Tokyo Valves 2023

In this session, review the anatomy of the aortic valve system, learn how to assess low-flow, low-gradient severe AS, identify the pitfalls to avoid when assessing paravalvular leakage after TAVI, and find out more about how to detect valve thrombosis and degeneration, among others!

Imaging for aortic valve interventions

The VitaFlow TAVI system - A new device that delivers exceptional patient outcomes

29 Nov 2022 – From PCR London Valves 2022

In this session, a panel of experts introduce the VitaFlow TAVI system, a good option for patients with complex anatomies. They also present the five-year results of VitaFlow in severe aortic stenosis.

Maintaining selective coronary access after TAVI and re-do TAVI procedures

28 Nov 2022 – From PCR London Valves 2022

Watch this session if you want to understand the various challenges when trying to get coronary access after TAVI, learn different techniques and discuss the options for coronary access after re-do TAVI.

Challenging scenarios: TAV-in-TAV procedures

28 Nov 2022 – From PCR London Valves 2022

Consult this session to discover some challenging TAV-in-TAV procedures, and learn more about the key role of imaging during pre-procedural work-up and the potential treatment options after TAVI bioprosthetic valve fracture.

Challenging scenarios: TAV-in-TAV procedures

Patient-prosthesis mismatch: surgical and transcatheter approaches - LIVE case

28 Nov 2022 – From PCR London Valves 2022

Consult this session to discover different surgical and transcatheter approaches:

  • Part 1: Bioprosthesis aortic valve stenosis
    A 73-year-old male, with diabetes, BMI 29, atrial fibrillation, history of SAVR 15 years ago (Perimount 27) presents a symptomatic severe surgical valve stenosis with a preserved LV function.
    During the live time...
Patient-prosthesis mismatch: surgical and transcatheter approaches

Innovations in transcatheter tricuspid valve intervention - LIVE case

28 Nov 2022 – From PCR London Valves 2022

Watch two very innovative tricuspid cases you've never seen before:

  • Part 1: TR replacement
    An 82-year-old male with chronic atrial fibrillation and completely PM dependent for 27 years, presents a symptomatic torrential TR and an enlarged annulus with a great gap. The operators implanted for the first time in...
Innovations in transcatheter tricuspid valve intervention

Create the future of TAVI - Optimisation of the procedure and patient pathway

27 Nov 2022 – From PCR London Valves 2022

Dive into this session to discover what can be improved today to be ready to treat future TAVI patient volumes. You'll also learn how to set up a successful TAVI coordinating team and adopt it in your hospital, and how to create a win-win partnership with...

Ensuring optimal TAVI outcomes - LIVE case

27 Nov 2022 – From PCR London Valves 2022

A 75-year-old female with diabetes and history of ischemic stroke 5 years ago presents a symptomatic severe aortic valve stenosis in a small annulus.
After pre-dilatation (18 mm balloon), the operators implant an Acurate neo2 23 mm with a sentinel cerebral embolic protection device. Watch them perform...

Ensuring optimal TAVI outcomes

How and when should I consider Drug Coated Balloons to treat de novo lesions?

31 Oct 2022

Discover the replay of this PCR Webinar on Drug Coated Balloons with F. Ribichini, F. Manterola and D. Mylotte.