John Davies
Latest contributions
Clinical decision making for CTO PCI strategy
22 May 2026 – From EuroPCR 2026
This session explores clinical decision-making in CTO PCI strategy through complex scenarios including multivessel CTO in ischemic cardiomyopathy, high-risk NSTEMI post-vein graft failure, and challenges in elderly patients. It emphasizes strategic planning and individualized approaches to optimize outcomes.
CTO PCI: an evolving landscape
21 May 2026 – From EuroPCR 2026
Review the evolving landscape of chronic total occlusion (CTO) PCI with a focus on recent trends, contemporary management in multivessel disease, and innovative techniques such as retrograde approaches and titrated contrast recanalization. This session also addresses cost-effectiveness and drug-coated balloon (DCB) therapy outcomes from multicenter studies.
CTO PCI: technical developments
19 May 2026 – From EuroPCR 2026
This session highlights technical developments in CTO PCI, featuring comparative insights from the ONUBA-CTO study on retrograde versus antegrade approaches, sex-based differences in long-term outcomes, management of balloon-undilatable lesions, the role of virtual reality audiovisual distraction, the impact of core laboratory feedback with OCT, and contemporary...
What does ORBITA CTO tell us about CTO PCI?
20 May 2026 – From EuroPCR 2026
Chronic total occlusions (CTOs) remain a key area of uncertainty in interventional cardiology, particularly regarding symptom improvement after PCI.
In this EuroPCR 2026 interview, John Davies and Sarosh Khan discuss the ORBITA CTO trial and its implications for clinical practice.
As the first double-blind, placebo-controlled randomised trial in...
A randomized, placebo-controlled trial of chronic total occlusion PCI in stable angina - ORBITA-CTO trial
03 Apr 2026
Kalaivani Mahadevan provides an in-depth analysis of the ORBITA-CTO trial: a first-ever randomised, double-blind, placebo-controlled trial evaluating CTO PCI in stable angina patients.
She also interviewed principal investigators Sarosh Khan and John Davies following the LBCT Scientific Session at ACC.26 in New Orleans and simultaneous publication in...

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Advancements in intracoronary imaging and intervention: unmasking vulnerable plaques and optimising durable PCI outcomes
16 May 2024 – From EuroPCR 2024
Delve into this EuroPCR 2024 session to gain insights into NIRS IVUS, exploring its applications, supported by current data, and understanding its clinical significance. Learn how to utilize NIRS IVUS in PCI planning through case examples, addressing lesion characteristics such as length and calcific nodules. Explore local...
Chronic total occlusions - miscellaneous
15 May 2024 – From EuroPCR 2024