Dr. Klaus Peter Rentrop

Klaus Peter Rentrop

NYU Langone Medical Center - New York, United States

Klaus Peter Rentrop (1948-)

Dr. Peter Rentrop graduated from the University of Heidelberg Medical School in 1966. From July 1968 through June 1973, he completed his training at Detroit General Hospital and the Cleveland Clinic where he learned coronary arteriography from Mason Sones. Working in Göttingen, Germany, Peter was in the research group who performed coronary angiography within the first hours of AMI. 


In 1979, to limit the size of an acute myocardial infarction, Peter performed the world’s first primary coronary intervention by mechanical recanalization of the occluded artery using guidewires. The following year, in 1980, Peter proposed the use of intracoronary thrombolysis with an infusion of streptokinase and noted lysis of the thrombus in 75% of the cases. The modern era of reperfusion was born. This revolutionary concept was evaluated in a clinical trial when Peter Rentrop moved in 1981 to Mount Sinai Hospital, New York and paved the way for direct treatment by balloon dilatation immediately after thrombolysis (Jürgen Meyer, Mainz, 1982), followed by primary angioplasty for the treatment of heart attacks (Geoffrey Hartzler, 1983). Later this strategy was referred to as the ST-segment Elevation Myocardial Infarction (STEMI) protocol for the treatment of acute myocardial infarction.